Qhov sib txawv tseem ceeb ntawm tylosin tartrate thiab tylosin phosphate yog tylosin tartrate yog absorbed zoo dua li tylosin phosphate tom qab tswj qhov ncauj.
Tylosin yog tshuaj tua kab mob macrolide thiab bacteriostatic pub additive uas muaj txiaj ntsig zoo hauv cov kws kho tsiaj. Cov tshuaj no muaj ntau yam kev ua ub no tiv thaiv kab mob Gram-zoo thiab ib qho kev txwv ntawm cov kab mob Gram-negative. Lawm, peb tuaj yeem pom nws hauv cov khoom fermentation ntawm Streptomyces fradiae.
Tylosin Tartrate yog dab tsi?
Tylosin tartrate yog cov organic compound uas muaj cov tshuaj formula C 50H83NO23Cov molar loj ntawm cov tshuaj no yog 1066.2 g / mol. Nws tuaj yeem piav qhia tias yog tshuaj tua kab mob macrolide uas tuaj yeem tau txais los ntawm kab lis kev cai ntawm Streptomyces fradiae. Cov tshuaj no zoo heev tiv thaiv ntau yam kab mob hauv cov tsiaj; txawm li cas los xij, nws tsis ua haujlwm rau tib neeg. Yog li ntawd, nws yog ib qho tseem ceeb nyob rau hauv kev tsim tsiaj tshuaj raws li ib tug antibacterial neeg sawv cev. Tylosin tartrate tseem hu ua Fradizine, hydrochloride Tylosin, Tylan, Tylosin, thiab Tylosin hydrochloride.
Tylosin tartrate muaj hydrogen daim ntawv pub dawb suav ntawm 9, thiab hydrogen daim ntawv lees txais suav ntawm qhov sib xyaw no yog 24. Tsis tas li ntawd, nws muaj 16., thiab nws muaj ib qho atom stereocenter suav ntawm 23.
Muaj ntau qhov kev tshawb fawb txog kev ua haujlwm ntawm cov tshuaj tua kab mob thiab kev ua haujlwm ntawm cov tshuaj no hauv cov tsiaj. Cov kev sim no tau ua tiav tsuas yog siv cov nas thiab nas. Piv txwv li, kev tswj hwm qhov ncauj ntawm tylosin tartrate rau hauv nas (>6200 mg / kg), kev tswj hwm cov tshuaj no rau hauv cov nas (koob tshuaj yog 695 mg / kg), thiab kev tswj hwm ntawm cov tshuaj no subcutaneously rau hauv nas (koob tshuaj yog 1354 mg / kg.) tuaj yeem ua rau muaj kev coj cwj pwm, convulsions, lossis cuam tshuam rau kev qaug dab peg.
YTylosin Phosphate yog dab tsi?
Tylosin phosphate yog cov organic compound uas muaj cov tshuaj formula C 46H80NO21 P. Cov molar mass ntawm no compound yog 1014.1 g / mol. Cov tshuaj no tseem hu ua Farmazin TB, Pharmasin TB. Nws muaj hydrogen daim ntawv cog lus pub suav ntawm 8 thiab hydrogen daim ntawv lees txais suav ntawm 22. Tsis tas li ntawd, cov nyiaj sib hloov pauv ntawm tylosin phosphate yog 13. Qhov nyuaj ntawm qhov sib xyaw no tuaj yeem muab tau raws li 1610 degrees. Tsis tas li ntawd, tylosin phosphate muaj cov ntsiab lus stereocenter suav ntawm 2. Zoo ib yam li tylosin tartrate, tylosin phosphate kuj tseem ceeb hauv kev tsim tshuaj tsiaj.
Tylosin phosphate tuaj yeem txhais tau tias yog tshuaj tua kab mob macrolide uas tuaj yeem ua cov tshuaj bacteriostatic. Yog li ntawd, nws yog ib qho tseem ceeb nyob rau hauv veterinary tshuaj. Ntxiv mus, nws muaj ntau yam kev ua ub no tawm tsam Gram-zoo kab mob thiab ib tug txwv ntau yam ntawm Gram-tsis zoo kab mob.
Qhov txawv ntawm Tylosin Tartrate thiab Tylosin Phosphate yog dab tsi?
Feem ntau, tylosin tartrate thiab tylosin phosphate yog siv los tsim cov tshuaj tsiaj vim lawv cov tshuaj tua kab mob. Qhov sib txawv tseem ceeb ntawm tylosin tartrate thiab tylosin phosphate yog tias tylosin tartrate yog absorbed zoo dua li tylosin phosphate tom qab tswj qhov ncauj.
Ntxiv mus, qhov nyuaj ntawm tylosin tartrate yog siab, thaum lub complexity ntawm tylosin phosphate yog tsawg (1700 thiab 1610 degrees, feem). Cov molar masses ntawm ob lub tebchaw no kuj txawv nyob ntawm cov mis molecular; 1066.2 g / mol thiab 1014.1 g / mol, feem, rau tylosin tartrate thiab tylosin phosphate.
Cov duab hauv qab no nthuav tawm qhov sib txawv ntawm tylosin tartrate thiab tylosin phosphate hauv daim ntawv teev npe rau kev sib piv ntawm ib sab.
Summary – Tylosin Tartrate vs Tylosin Phosphate
Tylosin tartrate yog cov organic compound uas muaj cov tshuaj formula C 50H83NO23 Tylosin phosphate yog cov organic compound uas muaj cov tshuaj formula C46H80NO21P. Qhov sib txawv tseem ceeb ntawm tylosin tartrate thiab tylosin phosphate yog qhov nqus ntawm tylosin tartrate zoo dua li ntawm tylosin phosphate tom qab tswj qhov ncauj.
