Qhov sib txawv tseem ceeb ntawm DMARDs thiab biologics yog DMARDs (Disease-Modifying Anti-Rheumatic Drugs) yog cov tshuaj siv uas tuaj yeem pab tiv thaiv kev sib koom ua ke thiab deformity los ntawm Rheumatoid Arthritis (RA) thaum biologics yog cov tshuaj kho caj ces tsim los ntawm tshuaj rau RA.
Rheumatoid Arthritis (RA) yog kab mob autoimmune uas cuam tshuam rau pob qij txha. Nws yog ib tug kab mob mus ntev uas ua rau sov, o thiab mob pob qij txha. Tus kab mob no tshwm sim thaum lub cev tiv thaiv kab mob ua yuam kev tawm tsam cov kab mob ntawm cov pob qij txha. Kev kho mob rau RA tuaj yeem nres qhov mob thiab o. DMARDs, biologics thiab Jak inhibitors yog peb hom tshuaj siv los kho thiab tswj kev mob RA hauv cov laus. DMARDs yog cov tshuaj ib txwm siv rau tag nrho lub cev tiv thaiv kab mob. Biologics, ntawm qhov tod tes, yog cov tshuaj tsim kho caj ces uas tsom cov kauj ruam tshwj xeeb hauv cov txheej txheem inflammatory. Biologics kim kim thiab muaj peev xwm cuam tshuam nrog lawv.
DMARDs yog dab tsi?
Disease-Modifying Anti-Rheumatic Drugs (DMARDs) yog cov tshuaj ib txwm siv los tiv thaiv kev sib koom ua ke thiab deformity los ntawm RA. Methotrexate yog thawj DMARDs uas yog hom ntau tshaj plaws. Hydroxychloroquine, mycophenolate, ciclosporin, cyclophosphamide thiab sulfasalazine yog ntau hom DMARDs. Cov tshuaj DMARDs no feem ntau tuaj ua tshuaj. DMARDs tsom tag nrho lub cev tiv thaiv kab mob, tsis zoo li biologics.
Daim duab 01: DMARD - Methotrexate
Different DMARDs ua rau muaj kev phiv sib txawv. Methotrexate tuaj yeem ua rau lub siab puas tsuaj, pob txha pob txha thiab kev nchuav menyuam. Cov qauv DMARDs ua haujlwm qeeb. Lawv siv lub hlis los teb. Txawm li cas los xij, piv rau biologics, DMARDs yog tus nqi zoo.
Dab tsi yog Biologics?
Biologics yog cov tshuaj kho caj ces rau RA. Lawv ua hauj lwm nyob rau hauv ib tug ntau lub hom phiaj nyob rau hauv thaiv cytokines. Lawv tsom cov kauj ruam tshwj xeeb hauv cov txheej txheem inflammatory. Feem ntau cov biologics muaj qhov ua tau sai dua li cov qauv DMARDs. Biologics tau muab rau cov neeg mob RA tom qab sim ua lwm yam kev kho mob ua ntej, thiab thaum lawv tsis teb. Tsis tas li ntawd, biologics tau muab ua ke nrog cov pa DMARD xws li methotrexate. Biologics kim dua thiab qhia tias muaj kev pheej hmoo siab dua thiab.
Daim duab 02: Biologics
Biologics yog txhaj rau hauv qab ntawm daim tawv nqaij. Lawv tuaj yeem muab tau los ntawm kev txhaj tshuaj infusion. Cov tshuaj tiv thaiv ntawm daim tawv nqaij yog qhov tshwm sim ntau tshaj plaws uas biologics qhia. Mob qog noj ntshav ntawm daim tawv nqaij yog ib qho kev mob tshwm sim loj heev uas biologics tuaj yeem ua rau. Abatacept, rituximab thiab tocilizumab yog ob peb biologics.
Dab tsi yog qhov sib txawv ntawm DMARDs thiab Biologics?
- DMARDs thiab biologics yog ob txoj kev kho mob rau RA.
- Ob hom tshuaj tuaj yeem ua rau muaj kev pheej hmoo kis mob.
- DMARDs tuaj yeem ua ke nrog biologics thiab siv.
- Ob leeg ua rau muaj kev phiv.
- Ntxiv mus, ob qho tib si muaj peev xwm txaus ntshai.
Qhov txawv ntawm DMARDs thiab Biologics yog dab tsi?
DMARDs yog cov tshuaj ib txwm siv los kho Rheumatoid Arthritis thaum biologics yog cov tshuaj tsim kho caj ces tsim los kho Rheumatoid Arthritis. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm DMARDs thiab biologics. Tsis tas li ntawd, DMARDs tsom rau tag nrho lub cev tiv thaiv kab mob thaum biologics tsom cov kauj ruam tshwj xeeb hauv cov txheej txheem inflammatory. Yog li, qhov no kuj yog qhov sib txawv loj ntawm DMARDs thiab biologics.
Ntxiv mus, biologics muaj kev pheej hmoo siab dua thiab tus nqi siab dua piv rau DMARDs. Tsis tas li, lwm qhov sib txawv ntawm DMARDs thiab biologics yog txoj kev xa khoom. DMARDs muaj nyob rau hauv cov ntsiav tshuaj thaum biologics yog txhaj.
Summary – DMARDs vs Biologics
DMARDs thiab biologics yog ob hom tshuaj siv los kho mob rheumatoid mob caj dab. DMARDs yog cov tshuaj classical lossis cov pa thiab muaj kev nyab xeeb rau kev siv. Lawv tuaj ua tshuaj. Biologics, ntawm qhov tod tes, yog cov tshuaj tsim kho caj ces uas ua tau zoo dua thiab kim dua. Lawv ua sai dua DMARDs. Tsis tas li ntawd, biologics tau tsom ntau dua li DMARDs. DMARDs, tsis zoo li biologics, tsom rau tag nrho lub cev tiv thaiv kab mob. Tsis tas li ntawd, biologics yog txhaj tshuaj. Yog li, qhov no qhia txog qhov sib txawv ntawm DMARDs thiab biologics.
