Biologics thiab biosimilars yog ob hom tshuaj. Qhov sib txawv tseem ceeb ntawm biologics thiab biosimilars yog tias kev tsim khoom biologics yuav tsum tau ua nyob rau hauv cov kab mob uas muaj sia nyob thaum biosimilars tsim tsis koom nrog cov kab mob nyob.
Nrog rau kev nce qib ntawm biotechnology, kev tsim cov tshuaj tau coj qhov tshiab. Kev tsim tshuaj yeeb hauv kev lag luam hauv ntiaj teb siv ntau hom kev sib txawv. Biologics yog cov tshuaj tshuaj tsim nyob rau hauv cov kab mob nyob. Cov kab mob no yuav yog prokaryotes xws li kab mob los yog eukaryotes xws li fungi thiab tsiaj txhu. Txoj kev loj hlob ntawm biologics yuav siv qhov chaw siv high-end biotechnological cov txheej txheem. Ntawm qhov tod tes, biosimilars yog cov tshuaj siv tshuaj zoo ib yam li cov tshuaj biologics tab sis tsis yog tsim los hauv cov kab mob uas muaj sia nyob. Yog li ntawd, cov tshuaj no tsis zoo ib yam, tab sis zoo ib yam. Txawm li cas los xij, muaj kev sib cav tsis tu ncua ntawm kev siv Biologics thiab Biosimilars hauv kev ua lag luam thiab nws qhov zoo, qhov tsis zoo, thiab nws cov kev mob tshwm sim.
Dab tsi yog Biologics?
Biologics yog cov tshuaj tshuaj uas tsim los ntawm cov kab mob muaj sia. Cov no suav nrog cov tshuaj tiv thaiv kab mob, cov tshuaj tiv thaiv kab mob metabolic thiab ntau cov proteins, thiab lwm yam. Txawm li cas los xij, cov tshuaj no muaj zog heev. Vim hais tias, biologics yog nyob ntawm seb lub cev yam xws li kub thiab pH. Tsis tas li ntawd, ib puag ncig ntawm kev cia yuav tsum ua raws li cov xwm txheej qub. Yog li ntawd, kev tsim cov biologics yog piv rau cov txheej txheem tedious. Tsis tas li ntawd, biologics tsim tau yooj yim los ntawm recombinant DNA technology. Yog li ntawd, cov neeg ua haujlwm tshwj xeeb yuav tsum tau koom nrog hauv cov txheej txheem.
Daim duab 01: Biologics
Dhau li ntawm, cov tshuaj biologics tuaj yeem npaj los ntawm txhua lub tuam txhab tshuaj, thiab muaj kev txwv tsawg dua. Muaj qhov pheej hmoo tsawg kawg uas cuam tshuam nrog kev siv biologics vim nws twb tsim los ntawm cov kab mob muaj sia. Tsis tas li ntawd, cov tshuaj biologic tuaj yeem muab ncaj qha rau tus neeg mob, thiab lawv tau pom muaj txiaj ntsig zoo hauv cov txheej txheem kho. Biologics uas siv nyob rau hauv tej yam kev mob xws li kab mob siab, mob ntshav qab zib mellitus thiab Rheumatoid mob caj dab tau pom tias yuav cog lus raws li kev kho mob.
Dab tsi yog Biosimilars?
Biosimilars yog cov tshuaj uas tsis ua ke hauv cov kab mob uas muaj sia nyob. Kev tsim cov biosimilars xav tau cov kab xov tooj tshwj xeeb uas tshwj xeeb rau cov chaw tsim khoom. Yog li ntawd, biosimilars ua raws li cov tshuaj biologic tab sis tsis zoo ib yam. Muaj peev xwm muaj qhov sib txawv ntawm qhov sib txawv ntawm biologics thiab biosimilars cov tshuaj tib lub sijhawm. Yog li ntawd, lawv xa cov ntawv luam ntawm cov tshuaj thawj zaug.
Dhau li ntawm, kev tsim cov biosimilars yog nyob ntawm cov chaw tsim khoom. Tom qab kev soj ntsuam nruj me ntsis txog cov tshuaj, nws cov khoom, nws cov tshuaj pharmacokinetic thiab nws tus cwj pwm, cov pab pawg tshawb fawb ntawm cov tuam txhab kws tshuaj tau tsim hauv vitro txoj kev tsim tshuaj. Tom qab ntawd, cov chaw tsim khoom ntawm cov tshuaj tau ua cov tshuaj tsim khoom lag luam hauv cov xov tooj ntawm tes yam tsis tau qhia txog tus kheej ntawm cov kab ntawm tes.
Daim duab 02: Biosimilars
Kev tsim cov biosimilars tau ua tau ntau dua vim tias lub cev tuaj yeem hloov pauv. Tab sis, vim li no, qhov tsis ua tiav ntawm biosimilars tuaj rau hauv kev ua lag luam yog siab. Nws yog vim hais tias, muaj ntau yam teeb meem cuam tshuam nrog biosimilars piv rau biologics. Yog li ntawd, kev siv biosimilars poob siab ntawm qee cov zej zog.
Dab tsi yog qhov zoo sib xws ntawm Biologics thiab Biosimilars?
- Biologics thiab Biosimilars yog cov tshuaj tshuaj.
- Ob hom tshuaj yuav tsum tau tshuaj xyuas hnyav ua ntej nkag mus rau theem kev sim tshuaj.
- Tsis tas li, ob qho tib si yuav tsum muaj kev sim ntau yam raws li tib neeg thiab tsiaj.
- Tsis tas li ntawd, ob qho tib si siv los kho cov kab mob sib kis thiab tsis kis kab mob.
- Lawv muaj cov qauv tseem ceeb thiab kev ua haujlwm zoo sib xws.
- Ntxiv mus, ob qho tib si zoo ib yam hauv lawv cov khoom siv tshuaj tshuaj.
Qhov txawv ntawm Biologics thiab Biosimilars yog dab tsi?
Biologics thiab biosimilars yog ob hom tshuaj. Qhov sib txawv tseem ceeb ntawm biologics thiab biosimilars yog kev koom tes ntawm cov kab mob nyob hauv lub sijhawm tsim khoom. Kev tsim khoom biologics suav nrog cov kab mob muaj sia thaum biosimilars tsis muaj. Tsis tas li ntawd, lwm qhov sib txawv ntawm biologics thiab biosimilars yog qhov recombinant DNA thev naus laus zis yog hom tseem ceeb ntawm biologics ntau lawm thaum nws tsis muaj txiaj ntsig hauv biosimilars ntau lawm.
Cov hauv qab no nthuav tawm cov ntsiab lus ntxiv ntawm qhov sib txawv ntawm biologics thiab biosimilars.
Summary – Biologics vs Biosimilars
Qhov kev tsis sib haum xeeb ntawm kev siv biologics thiab biosimilars tau ua rau muaj kev nkag siab tshiab ntawm cov zej zog kho mob. Biologics yog cov tshuaj tshuaj uas ua ke hauv cov kab mob uas muaj sia nyob. Recombinant DNA thev naus laus zis tau siv dav hauv kev tsim khoom siv biologics. Hauv qhov sib piv, biosimilars ua raws li cov biologics, tab sis lawv tsis zoo ib yam. Biosimilars ntau lawm tsis koom nrog cov kab mob nyob. Hloov chaw, lawv tau tsim nyob rau hauv cov chaw tsim khoom nyob ntawm tes. Li no, qhov no yog qhov txawv ntawm biologics thiab biosimilars.
