Qhov txawv ntawm thymine thiab thymidine yog thymine yog nucleobase, whereas thymidine yog nucleoside.
Lub sij hawm thymine thiab thymidine tshwm sim hauv biochemistry thiab organic chemistry raws li cov qauv muaj feem xyuam rau nucleic acids. Nucleic acid xws li DNA thiab RNA yog tsim los ntawm nucleotides. Lub nucleotide muaj nucleobase, qab zib molecule thiab ib pawg phosphate. Kev sib xyaw ua ke ntawm nucleobase nrog cov piam thaj ua rau nucleoside.
Thymine yog dab tsi?
Thymine yog ib hom nucleobase muaj cov tshuaj formula C5H6N2 O2 Nws yog cov organic compound uas muaj cov molar loj 126.15 g / mol. Nws yog ib qho ntawm plaub loj nucleobases hauv nucleic acids ntawm DNA. Lwm peb nucleobases yog guanine, cytosine thiab adenine. Qhov nucleobase no poob rau hauv qeb ntawm pyrimidine. Qhov no nucleobase tsis nyob hauv RNA; nws muaj uracil hloov thymine.
Daim duab 01: Cov Qauv Tshuaj ntawm Thymine
Thaum xav txog cov khoom ntawm thymine, nws ua ke nrog adenine hauv DNA qauv. Thymine yog muab los ntawm methylation ntawm uracil ntawm 5th carbon; Yog li ntawd, nws yog hu ua 5-methyluracil. Thymine tuaj yeem khi nrog adenine ntawm ob daim ntawv cog lus. Ob daim ntawv cog lus no yog ib khub ntawm hydrogen bonds. Ob daim ntawv cog lus hydrogen no pab tau kom ruaj khov DNA qauv thiab cov qauv nucleobase ib yam nkaus.
Kev tsim ntawm thymine dimers yog hom kev hloov pauv hauv DNA. Ntawm no, ib khub ntawm thymine uas nyob ib sab los yog cytosine tsim thymine dimers (tsim kev sib txuas ntawm cov nucleobases sib law liag) uas ua rau tsim cov kinks uas tuaj yeem cuam tshuam qhov kev ua haujlwm ntawm DNA. Tsis tas li ntawd, thymine bases tuaj yeem oxidized los tsim hydantoins. Qhov no tshwm sim tom qab lub cev tuag.
YThymidine yog dab tsi?
YThymidine yog ib hom pyrimidine deoxynucleoside muaj cov tshuaj formula C
10H14N2 O5 Cov molar pawg ntawm cov organic compound no yog 242.23 g / mol. Nws yog ib qho nucleoside tsim los ntawm kev sib xyaw ntawm thymine thiab deoxyribose qab zib. Cov nucleoside no tuaj yeem ua phosphorylated los tsim cov nucleotides. Ntawm no, nws yuav raug phosphorylation nrog ib pab pawg phosphate (cov ntaub ntawv no deoxythymidine monophosphate), nrog ob pawg phosphate (ua deoxythymidine diphosphate) lossis nrog peb pawg phosphate (tsim peb pawg phosphate).
Daim duab 02: Cov qauv tshuaj ntawm Thymidine
Thymidine tuaj yeem muaj nyob rau hauv vitro mob raws li cov khoom (raws li cov muaju dawb lossis dawb crystalline hmoov). Nyob rau hauv tus txheej txheem kub thiab siab, stability ntawm no compound yog siab heev. Raws li ib feem ntawm DNA qauv, thymidine tshwm sim hauv cov kab mob uas muaj sia nyob (tseem nyob hauv cov kab mob DNA). Yog li ntawd, nws yog ib qho tsis muaj tshuaj lom. Hauv RNA, muaj uridine tsis yog thymidine. Uridine yog tsim los ntawm kev sib xyaw ntawm uracil nrog ribose qab zib.
Qhov txawv ntawm Thymine thiab Thymidine yog dab tsi?
Qhov txawv ntawm thymine thiab thymidine yog tias thymine yog nucleobase, hos thymidine yog nucleoside. Tsis tas li ntawd, thymine yog ib hom nucleobase muaj cov tshuaj formula C5H6N2O 2 thaum thymidine yog hom pyrimidine deoxynucleoside muaj cov tshuaj formula C10H14N 2O5
Ntxiv mus, thymine yog tib lub qauv qauv molecule thaum thymidine yog kev sib xyaw ntawm ob lub molecules; ribose qab zib thiab thymine.
Cov lus hauv qab no qhia txog qhov sib txawv ntawm thymine thiab thymidine.
Summary – Thymine vs Thymidine
Lub sij hawm thymine thiab thymidine tuaj hauv biochemistry thiab organic chemistry raws li cov qauv muaj feem xyuam rau nucleic acids. Qhov sib txawv tseem ceeb ntawm thymine thiab thymidine yog thymine yog nucleobase, whereas thymidine yog nucleoside.
