Qhov Tseem Ceeb Qhov Sib Txawv - Tshuaj Khomob vs Hom Tshuaj Kho
Cancer yog suav tias yog ib qho ntawm cov kab mob uas muaj ntau tshaj plaws hauv ntiaj teb. Nws belongs rau ib tug sau los ntawm cov kab mob uas tshwm sim vim uncontrolled cell proliferation. Cancer tuaj yeem muaj ntau hom; mob cancer ntawm lub mis, mob ntsws cancer, mob qog nqaij hlav hauv plab, leukemia. Mob qog noj ntshav yog tshwm sim los ntawm kev hloov pauv ntawm peb lub noob; proto-oncogenes, qog suppressor noob, thiab DNA kho cov noob. Kev kho mob qog noj ntshav tam sim no yog lub ncauj lus nrov ntawm kev tshawb fawb. Chemotherapy thiab Targeted therapy yog ob yam tseem ceeb ntawm kev kho mob qog noj ntshav. Targeted therapy yog ib txoj kev kho mob tshwj xeeb uas siv cov tshuaj uas tuaj yeem thaiv cov synthesis, kev loj hlob, thiab kev sib kis ntawm cov biomolecules tshwj xeeb uas koom nrog hauv kev loj hlob ntawm qog noj ntshav. Kev kho mob khees xaws yog tej zaum yog hom kev kho mob cancer qub tshaj plaws uas siv cov tshuaj cytotoxic thiab tshuaj uas muaj peev xwm ua kom puas hlwb; ob hom malignant thiab non-malignant. Li no, nws yog nonspecific. Qhov sib txawv tseem ceeb ntawm chemotherapy thiab kev kho mob yog qhov tshwj xeeb ntawm kev kho mob. Tshuaj kho mob tsis yog tshwj xeeb thiab koom nrog kev puas tsuaj ntawm txhua hom cell, qhov kev kho mob Targeted tsom rau cov molecules tshwj xeeb txhawm rau tiv thaiv kev loj hlob ntawm cov qog nqaij hlav cancer.
Tshuaj Khomob yog dabtsi?
Tshuaj khomob yog hom kev kho mob kheesxaws uas siv thoob plaws ntiaj teb los kho txhua yam mob qog noj ntshav. Nws yog ib txoj kev kho mob. Txawm li cas los xij, nws qhov tshwj xeeb yog tsawg piv rau lwm txoj hauv kev. Kev kho mob siv tshuaj cytotoxic thiab tshuaj uas muaj peev xwm ua kom puas hlwb ntawm ib hom tshwj xeeb; lub ntsws hlwb, lub siab hlwb, cov ntshav. Tab sis nws tsis paub qhov txawv ntawm malignant thiab nonmalignant cell hom. Yog li ntawd, chemotherapy ua rau kev puas tsuaj ntawm ob lub hlwb noj qab haus huv thiab malignant hlwb. Tshuaj kho mob yog muab tso rau hauv cov hlab ntsha, thiab lawv muaj kev lag luam muaj nyob rau hauv cov ntim ntim nrog cov cim ceeb toom tsim nyog.
Daim duab 01: Kev kho mob tshuaj khomob
Cov tshuaj khomob muaj cov txheej txheem sib txawv uas lawv ua rau cov hlwb puas. Qee qhov mechanisms yog;
- Kev thaiv kev hloov pauv ntawm cov noob tsim cov hlwb.
- Txo qhov ceev ntawm cov qog nqaij hlav qog noj ntshav.
- Targeting kev puas tsuaj ntawm cell membrane.
- Inhibition ntawm cov txheej txheem kev noj zaub mov ntawm cov hlwb.
Tshuaj khomob tuaj yeem siv tau ua ib qho tshuaj lossis ua ntau hom tshuaj siv ntau yam tshuaj uas tsom mus rau ntau hom cell. Hom kws khomob yog nyob ntawm lub xeev ntawm mob qog noj ntshav, hom mob qog noj ntshav thiab cov xwm txheej ntawm tus neeg mob. Chemotherapy muaj kev phiv los ntawm kev sib piv rau lwm cov txheej txheem kho. Nws yog vim kev puas tsuaj ntawm cov hlwb noj qab haus huv. Qee qhov kev mob tshwm sim yog,
- Hair poob
- teeb meem ua pa
- Kab mob hauv qhov ncauj thiab raws plab lossis kab mob ua pa
- mob thiab mob.
Kev Kho Mob Puas Yog Dab Tsi?
Tim phiaj kho mob yog ib hom kev kho mob tshwj xeeb tiv thaiv kab mob qog noj ntshav uas tsom rau cov molecules tshwj xeeb uas txhawb nqa cov qog nqaij hlav cancer. Cov tshuaj tiv thaiv kab mob feem ntau yog cytostatic. Lawv txwv txoj kev loj hlob ntawm cov qog nqaij hlav cancer. Yog li ntawd, lawv tsis yog tshwj xeeb yog cytotoxic. Cov kev kho mob sib txawv tau raug pom zoo thoob ntiaj teb los siv ua kev kho mob qog noj ntshav. Lawv suav nrog; Kev kho cov tshuaj hormones, cov teeb liab transduction inhibitors, gene expression modulators, apoptosis inducers, angiogenesis inhibitors, immunotherapies, thiab toxin delivery molecules.
Daim duab 02: Kev kho mob hom phiaj
Cov hom phiaj kho mob feem ntau siv cov tshuaj tiv thaiv kab mob monoclonal ua tus neeg nruab nrab ntawm kev kho mob. Lawv raug txhaj tshuaj los ntawm kev txhaj tshuaj. Lawv khi rau cov antigens tshwj xeeb ntawm cov hom phiaj molecular. Qhov kev khi no ua rau tsis ua haujlwm ntawm lub hom phiaj molecular tshwj xeeb uas ua rau inhibits kev loj hlob ntawm cov qog nqaij hlav cancer.
Targeted therapy yog ib qho kev kho mob tshiab uas suav nrog cov txheej txheem tshuaj kho tus kheej. Yog li, nws yog cov txheej txheem kim tab sis suav tias muaj pes tsawg tus ntawm cov kev mob tshwm sim hauv kev sib piv nrog rau lwm txoj kev kho mob qog noj ntshav. Qhov txo qis ntawm cov kev mob tshwm sim yog vim qhov tshwj xeeb ntawm cov txheej txheem kho. Cov hlwb noj qab haus huv tsis raug puas tsuaj los ntawm cov phiaj xwm kho.
Dab tsi yog qhov zoo sib xws ntawm Tshuaj Kho Mob thiab Kev Kho Mob?
- Ob leeg yog txoj kev kho mob uas siv los kho mob qog noj ntshav.
- Ob txoj kev kho mob yog muab tso rau hauv txoj hlab ntshav.
- Ob txoj kev kho mob tuaj yeem muab tshuaj ua ib qho tshuaj lossis ib pawg tshuaj.
Qhov txawv ntawm Kev Kho Mob thiab Kev Kho Mob Lub Hom Phiaj yog dab tsi?
Chemotherapy vs Targeted Therapy |
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| Tshuaj khomob yog ib txoj kev kho mob uas siv tshuaj cytotoxic los rhuav tshem cov hlwb uas suav nrog cov qog nqaij hlav cancer. | Targeted therapy yog ib txoj kev kho mob uas cov tshuaj uas siv cov tshuaj molecules tshwj xeeb yog siv txhawm rau txhawm rau tiv thaiv qog noj ntshav. |
| Specificity | |
| Tshuaj khomob tsis yog - tshwj xeeb lossis tsawg dua. | Kev kho mob yog qhov tshwj xeeb heev. |
| Tshuaj khomob yog cytotoxic- rhuav tshem cov hlwb. | Cov tshuaj kho mob yog cytostatic - inhibits qog nqaij hlav qog noj ntshav. |
| Cell / cell nto receptors yog cov nyhuv ntawm cov tshuaj kho mob. | Lub hom phiaj Molecular yog cov txiaj ntsig ntawm cov tshuaj kho mob. |
| Type | |
| Kev tswj hwm tshuaj cytotoxic ib leeg thiab ntau qhov kev tswj hwm tshuaj cytotoxic yog hom tshuaj kho mob. | Kev kho lub hom phiaj tuaj yeem muaj ntau hom kev kho mob raws li hom kev txwv. |
| Muaj ntau yam kev mob tshwm sim ntawm kws khomob raws li nws tuaj yeem rhuav tshem cov hlwb zoo ib yam. | Kev kho lub hom phiaj muaj kev phiv tsawg dua. |
Summary – Chemotherapy vs Targeted Therapy
Kev kho mob qog noj ntshav yog ib txoj kev kho mob uas nrov tshaj plaws hauv ntiaj teb vim muaj kev mob qog noj ntshav ntau thoob ntiaj teb. Lub hom phiaj kev kho mob thiab kws khomob yog ob txoj kev kho tshuaj uas siv hauv kev kho mob qog noj ntshav. Lawv txawv ntawm lawv qhov tshwj xeeb. Qhov sib txawv ntawm ob txoj kev kho mob no yog qhov Kev Kho Mob Lub Hom Phiaj yog qhov tshwj xeeb heev thaum kws khomob tsis yog. Feem ntau ob txoj kev kho mob no yog siv raws li txoj kev kho mob uas tau hais tseg los tiv thaiv mob qog noj ntshav. Ntau qhov kev tshawb fawb tseem tab tom tsim los tsim cov tshuaj tshwj xeeb uas muaj kev phiv tsawg dua.
Download the PDF Version of Chemotherapy vs Targeted Therapy
Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline lub hom phiaj raws li daim ntawv ceeb toom. Thov rub tawm PDF version ntawm no Qhov txawv Ntawm Cov Tshuaj Kho Mob thiab Kev Kho Mob
