Qhov sib txawv tseem ceeb ntawm Ubiquinol thiab CoQ10 yog tias ubiquinol yog ib daim ntawv txo kom tiav, hos CoQ10 yog ib daim ntawv oxidized tag.
Ubiquinol thiab CoQ10 yog cov khoom tseem ceeb hauv tib neeg lub cev koom nrog ntau txoj hauv kev. Cov ntsiab lus ubiquinol thiab CoQ10 xa mus rau cov ntawv txo lossis oxidized ntawm tib lub molecule/compound.
YUbiquinol yog dab tsi?
Ubiquinol tuaj yeem txhais tau tias yog daim ntawv nplua nuj electron ntawm coenzyme Q10. Daim ntawv tshwm sim ntawm ubiquinol muaj npe nyob rau hauv IUPAC system li 2, 3-dimethoxy-5-methyl-6-poly prenyl-1, 4-benzoqionol. Nws muaj polyprenylated sab saw, uas yog 9-10 units ntev hauv cov tsiaj.
Muaj peb hom loj ntawm coenzyme Q10 hauv peb lub xeev redox: ubiquinone, semiquinone, thiab ubiquinol. Ubiquinone yog lub xeev oxidized tag nrho. Semiquinone lossis ubisemiquinone yog ib feem ntawm lub xeev txo, thaum ubiquinol yog lub xeev txo tag nrho.
Daim duab 01: Ubiquinol
Cov tshuaj formula ntawm ubiquinol yog C59H92O4 Cov molar loj ntawm Qhov sib xyaw no yog 865.38 g / mol. Cov tsos tuaj yeem muab ua cov hmoov dawb dawb. Lub melting point ntawm ubiquinol yog 45.6 degrees Celsius. Nws yog xyaum insoluble nyob rau hauv dej. Ntxiv mus, nws tsis raug cais raws li cov vitamin vim tib neeg tuaj yeem tsim cov ubiquinol hauv lub cev.
Thaum xav txog bioavailability ntawm ubiquinol, nws muaj kev txhim kho bioavailability piv rau coQ10 vim tias nws muaj ob lub hydrogens ntxiv uas tuaj yeem ua rau hloov pauv ntawm ob pawg ketone rau hauv pawg hydroxyl ntawm qhov active feem ntawm cov molecule. Cov hydrogens ntxiv no tuaj yeem ua kom cov polarity ntawm cov molecule, ua kom muaj kev txhim kho bioavailability.
Ubiquinol yog cov khoom txo qis ntawm ubiquinone. Tus Tsov tus tw ntawm no compound muaj 10 isoprene units. Ubiquinone tuaj yeem txo qis rau ubiquinol ntawm txoj haujlwm I thiab II hauv cov saw hlau hloov hluav taws xob. Qhov no tuaj yeem pom hauv Q voj voog, uas cytochrome b hloov ubiquinol rau hauv ubiquinone hauv cov qauv cyclic. Nyob ntawd, thaum ubiquinol raug khi rau cytochrome b, pKa ntawm phenolic pawg txo qis, ua rau tsim cov phenoxide anion ntawm proton ionization.
CoQ10 yog dab tsi?
CoQ10 lossis coenzyme Q10 yog tsev neeg ntawm coenzymes uas tuaj yeem pom hauv cov tsiaj thiab cov kab mob feem ntau. Nws kuj tseem hu ua ubiquinone. Qhov no yog vim muaj peb hom loj ntawm coenzyme Q10: ubiquinone, semiquinone, thiab ubiquinol.
Daim duab 02: Cov Qauv Tshuaj ntawm CoQ10
Daim ntawv tshaj plaws uas peb tuaj yeem pom hauv tib neeg yog coenzyme Q10 lossis ubiquinone-10. Txawm li cas los xij, ubiquinone tsis tau pom zoo los ntawm FDA rau kev kho mob txhua yam mob. Tab sis nws tuaj yeem siv los ua khoom noj khoom haus thiab tseem muaj nyob hauv qee cov tshuaj pleev ib ce.
Cov tshuaj formula ntawm CoQ10 yog C59H90O4 Nws molar mass yog 863.36 g / mol. Nws tshwm raws li cov khoom daj lossis txiv kab ntxwv. Lub melting point ntawm CoQ10 nyob ntawm 48-52 degrees Celsius, thiab nws yog insoluble nyob rau hauv dej. Peb tuaj yeem categorize nws li 1, 4-benzoquinone. Ntawm no, tsab ntawv Q hauv Coenzyme Q10 yog hais txog tus naj npawb ntawm isoprenyl chemical subunits pom hauv nws tus Tsov tus tw. Ib txwm tshwm sim ubiquinones muaj 6-0 subunits.
Ntxiv mus, CoQ10 molecule tuaj yeem ua raws li ob lub tshuab hluav taws xob thiab ib lub tshuab hluav taws xob uas yog lub hauv paus rau lub luag haujlwm ntawm cov khoom sib xyaw no hauv cov khoom siv hluav taws xob thauj khoom vim cov hlau-sulfur pawg. Cov pawg no tuaj yeem txais tsuas yog ib lub tshuab hluav taws xob ib zaug xwb. Ntxiv mus, nws tuaj yeem ua raws li cov dawb-radical-scavenging antioxidant.
Qhov txawv ntawm Ubiquinol thiab CoQ10 yog dab tsi?
CoQ10 molecule tuaj yeem muaj nyob hauv peb theem: daim ntawv oxidized tag, daim ntawv txo qis, thiab daim ntawv txo kom tiav. Daim ntawv oxidized tag nrho yog ubiquinone, thiab nws tseem hu ua CoQ10. Daim ntawv txo tag nrho yog ubiquinol. Yog li ntawd, qhov sib txawv tseem ceeb ntawm Ubiquinol thiab CoQ10 yog tias ubiquinol yog ib daim ntawv txo kom tiav, hos CoQ10 yog ib daim ntawv oxidized tag.
Cov ntawv qhia hauv qab no nthuav tawm qhov sib txawv ntawm Ubiquinol thiab CoQ10 hauv daim ntawv teev npe rau kev sib piv ntawm ib sab.
Summary – Ubiquinol vs CoQ10
Ubiquinol tuaj yeem txhais tau tias yog daim ntawv nplua nuj electron ntawm coenzyme Q10. CoQ10 los yog coenzyme Q10 yog ib tsev neeg ntawm coenzymes uas tuaj yeem pom nyob rau hauv cov tsiaj thiab feem ntau cov kab mob. Qhov sib txawv tseem ceeb ntawm Ubiquinol thiab CoQ10 yog tias ubiquinol yog ib daim ntawv txo qis, thaum CoQ10 yog daim ntawv oxidized tag. Ntxiv mus, ubiquinol yog piv ntau dua polar dua CoQ10 vim muaj cov hydrogen atoms ntxiv.
