Qhov sib txawv tseem ceeb ntawm beta glucan 1 3 thiab 1 6 yog tias beta-glucan 1 3 tsim cov qauv microfibrillar, whereas beta-glucan 1 6 tsim cov qauv amorphous.
Beta-glucan 1 3 thiab beta-glucan 1 6 yog cov derivatives ntawm glucan suab thaj uas sib txawv ntawm ib leeg raws li cov qauv tshuaj thiab kev sib txuas.
Beta Glucan 1 3 yog dab tsi?
Beta-glucan 1 3 lossis beta-1, 3-glucan yog cov piam thaj polymer uas txuas los ntawm 1, 3-glycosidic bonds. Feem ntau, beta-1, 3 glucan yog branched. Nws muaj cov chains sab uas txuas rau lub nraub qaum los ntawm 1, 6-kev sib txuas. Feem ntau, beta-1, 3 glucan qhia txog peb npaug helical qauv, thiab nws yaj hauv cov tshuaj alkaline. Ntxiv mus, cov tshuaj no qhia tau hais tias muaj zog tiv thaiv kab mob-modulating teebmeem. Qhov no tshwm sim vim hais tias cov tshuaj no muaj peev xwm mus qhib cellular thiab humoral Cheebtsam ntawm tus tswv tsev tiv thaiv kab mob. Callose thiab curdlan yog beta-1 3 glucans.
Beta 1 3 glucan feem ntau yog ib qho tseem ceeb ntawm txhua qhov ntawm cov phab ntsa ntawm cov kab mob fungal. Qhov no ua rau ntawm 30% thiab 80% ntawm qhov loj ntawm phab ntsa. Ntxiv mus, qhov sib xyaw no tshwm sim nyob rau hauv daim ntawv ntawm cov phab ntsa ntawm tes. Yog li ntawd, nws tau kawm zoo raws li lub cell phab ntsa tsev thaiv.
Ntau yam kev ua haujlwm lom neeg ntawm beta-glucan 1 3 los ntawm nws cov qauv tshwj xeeb. Piv txwv li, nws tuaj yeem tswj hwm tib neeg lub cev tiv thaiv kab mob, thiab peb tuaj yeem siv nws ua cov tshuaj tiv thaiv antigen. Qhov no tseem ceeb hauv kev txhim kho kev tiv thaiv kab mob.
Beta Glucan 1 6 yog dab tsi?
Beta glucan 1 6 lossis beta-1, 6 glucan yog ib qho tseem ceeb ntawm S. ceravisiae thiab C. albicans cell phab ntsa. Raws li qee qhov kev tshawb fawb, nws pom tias yog ib qho tseem ceeb hauv C. neoformans cell phab ntsa. Ntxiv mus, muaj kev sib txuas ntawm beta-1, 6 glucans thiab beta-1, 3 glucans hauv chitin tam sim no hauv S.cerevissiae nrog rau GPI thauj tog rau nkoj oligosaccharide. Kev tsim ntawm crosslinks nrog GPI thauj tog rau nkoj thiab cell phab ntsa matric tuaj yeem sib txuas cov GPI-anchored cell phab ntsa proteins rau ntawm phab ntsa ntawm tes. Yog li, beta 1 6 glucan nyiam ua lub luag haujlwm tseem ceeb thaum lub sijhawm tsim ntawm S. cerevisiae cell phab ntsa matrix.
Beta-1, 6 glucan synthase yog ib qho enzyme uas tseem nyob rau hauv kev sim kom paub meej cov kab mob fungal. Nws ntseeg tau tias yog cov enzyme uas ua rau beta-1, 6 glucan. Txawm li cas los xij, muaj ntau cov noob uas tuaj yeem cuam tshuam cov synthesis ntawm beta-1, 6 glucan uas tshwm sim hauv S. cerevisiae. e.g. KRE5, BIG1, thiab ROT1 proteins.
Ntxiv mus, beta-1 6 glucan tuaj yeem txheeb xyuas tau tias yog qhov thib ob beta-txuas glucan ntawm phab ntsa cell hauv S- cerevisiae. Thaum xav txog cov noob qoob loo, muaj li ntawm 12% ntawm beta-1, 6 glucan, uas ua rau lub cell phab ntsa polysaccharide.
Qhov txawv ntawm Beta Glucan 1 3 thiab 1 6 yog dab tsi?
Glucan tuaj yeem siv los ua kev noj zaub mov ntxiv, thiab ntau hom tshuaj ntxiv yog beta 1, 3/1, 6 glucan ntxiv. Nws muaj ob qho tib si glucan 1 3 thiab glucan 1 6 beta daim ntawv. Qhov sib txawv tseem ceeb ntawm beta glucan 1 3 thiab 1 6 yog tias beta-glucan 1 3 ua rau cov qauv microfibrillar, thaum beta-glucan 1 6 tsim cov qauv amorphous. Ntxiv mus, beta-glucan 1 3 muaj qib siab ntawm polymerization thaum beta-glucan 1 6 muaj qib siab ntawm polymerization.
Cov hauv qab no infographic nthuav tawm qhov sib txawv ntawm beta glucan 1 3 thiab 1 6 hauv daim ntawv teev npe rau kev sib piv ntawm ib sab.
Summary – Beta Glucan 1 3 vs 1 6
Beta-glucan 1 3 lossis beta-1, 3-glucan yog cov piam thaj polymer uas txuas los ntawm 1, 3-glycosidic bonds. Beta glucan 1 6 los yog beta-1, 6 glucan yog ib qho tseem ceeb ntawm S. ceravisiae thiab C. albicans cell phab ntsa. Qhov sib txawv tseem ceeb ntawm beta glucan 1 3 thiab 1 6 yog tias beta-glucan 1 3 ua rau cov qauv microfibrillar, thaum beta-glucan 1 6 tsim cov qauv amorphous.
