Qhov txawv ntawm Vasculogenesis thiab Angiogenesis yog dab tsi

Cov txheej txheem:

Qhov txawv ntawm Vasculogenesis thiab Angiogenesis yog dab tsi
Qhov txawv ntawm Vasculogenesis thiab Angiogenesis yog dab tsi

Video: Qhov txawv ntawm Vasculogenesis thiab Angiogenesis yog dab tsi

Video: Qhov txawv ntawm Vasculogenesis thiab Angiogenesis yog dab tsi
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Qhov sib txawv tseem ceeb ntawm vasculogenesis thiab angiogenesis yog vasculogenesis hais txog de novo synthesis ntawm cov hlab ntsha thaum lub sij hawm embryonic txoj kev loj hlob, thaum angiogenesis hais txog cov synthesis ntawm cov hlab ntsha los ntawm pre-muaj hlwb nyob rau hauv lub neej.

Vasculogenesis thiab angiogenesis yog cov txheej txheem tseem ceeb hauv kev txhim kho thiab kev saib xyuas lub neej. Txawm li cas los xij, vasculogenesis tshwm sim thaum ntxov tom qab kev xeeb tub, thaum angiogenesis tshwm sim thoob plaws lub neej thiab yog txheej txheem tseem ceeb hauv kev kho kev puas tsuaj. Ntxiv mus, angiogenesis tseem ua lub luag haujlwm tseem ceeb hauv kev mob qog noj ntshav.

YVasculogenesis yog dab tsi?

Vasculogenesis yog hais txog de novo synthesis ntawm cov hlab ntsha los ntawm kev sib txawv ntawm endothelial precursor cells. Nws tshwm sim thaum lub sij hawm embryonic txoj kev loj hlob. Vasculogenesis ua rau txoj kev loj hlob ntawm cov hlab ntsha, lub plawv thiab ib puag ncig daim nyias nyias thaum lub sij hawm embryonic txoj kev loj hlob. Cov hlwb primitive uas pib vasculogenesis yog endothelial precursor hlwb. Cov hlwb endothelial no tshwm sim thaum lub sij hawm sib cais ntawm mesodermal hlwb hauv ob sab phlu hauv cov pob txha. Lawv induce loj hlob yam tseem ceeb hu ua fibroblast kev loj hlob yam uas ua rau cov hlwb precursor los npaj rau hauv cov hlab ntsha. Cov hlwb no txawv ntawm mesoderm. Cov hlwb mesodermal ces tsim mus rau hauv endothelial progenitor cells. Lawv muaj peev xwm loj hlob thiab tsiv mus nyob rau qhov chaw. Tom qab ntawd, ua ke nrog cov hlwb muab los ntawm cov qia hlwb hematopoietic, lawv tsim cov vascular network.

Vasculogenesis vs Angiogenesis
Vasculogenesis vs Angiogenesis

Daim duab 01: Cov Ntshav

Lub paracrine signaling system kuj ua lub luag haujlwm tseem ceeb hauv lub koom haum ntawm cov hlab ntsha thaum lub sij hawm embryonic txoj kev loj hlob. Ntxiv mus, cov noob caj noob ces kuj txiav txim siab vasculogenesis ntawm ib tug neeg. Yog li ntawd, raws li cov txheej txheem caj ces, kev kwv yees ntawm qhov txawv txav ntawm vasculogenesis tuaj yeem txiav txim siab. Nws ntxiv rau kev kuaj mob ntawm cov kab mob vascular ntsig txog kab mob thaum lub sijhawm embryonic.

Angiogenesis yog dab tsi?

Angiogenesis yog hais txog cov txheej txheem uas cov hlab ntsha synthesis tshwm sim los ntawm cov hlab ntsha uas twb muaj lawm. Yog li ntawd, nws tsis yog ib txoj kev de novo ntawm txoj hlab ntsha. Angiogenesis tshwm sim thoob plaws hauv lub neej. Nws yog txheej txheem rov ua dua. Hauv qhov sib piv, vasculogenesis tsuas yog tshwm sim thaum ntxov. Angiogenesis yog cov txheej txheem tseem ceeb hauv kev kho cov qe ntshav hauv lub cev.

Angiogenesis tshwm sim thaum lub xovtooj ntawm tes ua rau sprouting, vim kev puas tsuaj lossis raug mob. Cov hlwb endothelial yog li muaj peev xwm zais cov metalloproteases uas tuaj yeem zom cov kab hauv qab daus. Nws tso cai rau cov hlwb endothelial khiav mus rau cov ntaub so ntswg peripheral. Kev khiav tawm ntawm cov kab mob endothelial no yuav ua rau muaj kev loj hlob ntawm cov hlwb hauv qhov chaw tshiab.

Qhov txawv ntawm Vasculogenesis thiab Angiogenesis
Qhov txawv ntawm Vasculogenesis thiab Angiogenesis

Daim duab 02: Angiogenesis

Angiogenesis nrawm nrawm thaum mob qog noj ntshav. Kev nthuav qhia ntawm vascular endothelial kev loj hlob zoo yog siab thaum mob qog noj ntshav; Yog li, ua rau ntau tus nqi ntawm angiogenesis. Nws yuav ua rau muaj ntau cov as-ham rau cov qog nqaij hlav cancer proliferating uas ua rau muaj kev ruaj ntseg ntawm tes.

Dab tsi zoo sib xws ntawm Vasculogenesis thiab Angiogenesis?

  • Vasculogenesis thiab angiogenesis ua rau cov hlab ntsha tshiab.
  • Ob txheej txheem tshwm sim los ntawm kev koom tes ntawm cov hlwb endothelial thiab endothelial loj hlob yam.
  • Ntxiv mus, ob txheej txheem yog ua ntej txiav txim siab los ntawm cov noob caj noob ces.

Qhov txawv ntawm Vasculogenesis thiab Angiogenesis yog dab tsi?

Txawm hais tias ob lo lus no hais txog kev sib txuas ntawm cov hlab ntsha, muaj qhov sib txawv ntawm vasculogenesis thiab angiogenesis raws li lawv qhov tshwm sim, kev ua haujlwm thiab lub luag haujlwm lom neeg. Vasculogenesis, uas tshwm sim thaum lub sij hawm embryonic txoj kev loj hlob ntawm ib tug neeg, yog tus txheej txheem ntawm de Novo cov hlab ntsha synthesis. Yog li ntawd, nws ua rau kev tsim ntawm tag nrho cov hlab ntsha hauv lub cev. Txawm li cas los xij, angiogenesis tuaj yeem tshwm sim thaum lub sij hawm txhua theem ntawm lub neej thiab feem ntau ua haujlwm raws li kev kho kho. Yog li, angiogenesis yog hais txog kev sib txuas ntawm cov hlab ntsha los ntawm cov hlab ntsha uas twb muaj lawm. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm vasculogenesis thiab angiogenesis.

Cov hauv qab no qhia txog qhov sib txawv ntawm vasculogenesis thiab angiogenesis.

Qhov sib txawv ntawm Vasculogenesis thiab Angiogenesis hauv Tabular Form
Qhov sib txawv ntawm Vasculogenesis thiab Angiogenesis hauv Tabular Form

Summary – Vasculogenesis vs Angiogenesis

Vasculogenesis thiab angiogenesis yog ob txoj haujlwm tseem ceeb uas pab txhawb kev sib txuas ntawm cov hlab ntsha. Raws li, vasculogenesis hais txog de novo synthesis ntawm cov hlab ntsha. Txawm li cas los xij, lo lus angiogenesis yog hais txog kev sib txuas ntawm cov hlab ntsha los ntawm cov hlab ntsha uas twb muaj lawm. Tsis tas li ntawd, thaum vasculogenesis tshwm sim thaum ntxov kev loj hlob, angiogenesis tshwm sim raws li qhov yuav tsum tau ua tom qab raug mob los yog qhov txhab ntawm endothelium. Ntxiv mus, lub luag hauj lwm ua si los ntawm angiogenesis thaum lub sij hawm mob qog noj ntshav yog qhov tseem ceeb rau elucidate lub molecular mechanisms ua rau kev loj hlob ntawm mob qog noj ntshav. Yog li, qhov no yog cov ntsiab lus ntawm qhov sib txawv ntawm vasculogenesis thiab angiogenesis.

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