Qhov sib txawv tseem ceeb ntawm fucose thiab rhamnose yog tias fucose yog ib qho aldohexose tam sim no nyob rau hauv ntau glycans thiab mucopolysaccharides, whereas rhamnose yog ib tug methyl pentose uas tshwm sim nyob rau hauv nplooj thiab paj ntawm tshuaj lom ivy thiab kuj raws li ib tug constituent ntawm ntau cov nroj tsuag glycosides.
Fucose thiab rhamnose yog deoxy qab zib sib koom cov tshuaj tib yam, tab sis lawv muaj cov qauv tshuaj sib txawv uas sawv cev rau cov khoom sib txawv.
Fucose yog dab tsi?
Fucose yog hexose deoxy qab zib uas muaj cov tshuaj formula C6H12O5 Peb tuaj yeem pom qhov sib xyaw no ntawm N-txuas glycans ntawm cov tsiaj nyeg, kab, thiab cov nroj tsuag ntawm tes. Cov suab thaj no tuaj yeem piav qhia raws li qhov tseem ceeb ntawm cov seaweed polysaccharide fucoidan.
Daim duab 01: Cov Qauv Tshuaj ntawm Fucose
Nws muaj ob qhov sib txawv loj ntawm fucose thiab lwm yam 6-tus tswvcuab carbon suab thaj hauv cov tsiaj txhu: qhov tsis muaj hydroxyl pawg ntawm cov pa roj carbon ntawm txoj haujlwm 6 thiab L-kev teeb tsa. Cov tshuaj no sib npaug rau 6-deoxy-L-galactose.
Cov qauv glycan uas muaj fucose units yog hu ua fucosylated glycans. Hauv cov qauv no, fucose tuaj yeem tawm los ua qhov hloov pauv hloov pauv lossis ua haujlwm txuas ntxiv uas tuaj yeem taw qhia ntxiv rau lwm cov suab thaj. Tib neeg lub cev muaj N-txuas glycans. Nyob ntawd, fucose tuaj yeem pom txuas alpha-1, 6 mus rau lub davhlau ya nyob twg beta-N-acetylglucosamine. Cov fucose units uas twb muaj lawm nyob rau hauv tsis-txo terminals txuas alpha-1.2 mus rau galactose, tsim ib qho H antigen, uas yog lub substructure ntawm A thiab B cov ntshav pawg antigens.
Ntxiv mus, fucose tau tso tawm los ntawm fucose-muaj polymers los ntawm ib qho enzyme hu ua alpha-fucosidase uas tuaj yeem pom hauv lysosomes. Tsis tas li ntawd, L-fucose qhia tau hais tias muaj ntau yam kev siv hauv tshuaj pleev ib ce, tshuaj, thiab tshuaj noj.
Rhamnose yog dab tsi?
Rhamnose los yog rham yog ib txwm tshwm sim deoxy qab zib uas muaj cov tshuaj formula C6H12O5Peb tuaj yeem faib nws raws li methyl-pentose lossis 6-deoxy-hexose. Feem ntau, qhov sib xyaw no tshwm sim hauv qhov xwm txheej li L-rhamnose. Txij li feem ntau ntawm cov suab thaj uas tshwm sim ib txwm muaj nyob rau hauv D-daim ntawv, qhov ntau ntawm L-rhamnose yog qhov txawv heev. Txawm li cas los xij, muaj L-fucose thiab L-arabinose nyob rau hauv cov ntaub ntawv ntau ntawm lawv cov suab thaj zoo ib yam. Txawm li cas los xij, muaj D-rhamnose molecules uas peb tuaj yeem pom tshwm sim hauv qhov xwm txheej, piv txwv li, hauv qee hom kab mob xws li Pseudomonas aeruginosa thiab Helicobacter pylori.
Daim duab 02: Cov Qauv Tshuaj ntawm Rhamnose
Cov molar loj ntawm cov suab thaj no yog 164.15 g / mol. Nws muaj qhov ceev ntawm 1.41 g / cm3. Lub melting point ntawm rhamnose tuaj yeem nyob ntawm 91 txog 93 degrees Celsius. Peb tuaj yeem cais cov tshuaj no los ntawm Buckthorn tshuaj lom sumac thiab qee cov nroj tsuag hauv genus Uncaria. Ntxiv mus, rhamnose tuaj yeem tsim los ntawm microalgae, uas yog nyob rau hauv chav kawm ntawm Bacillariophyceae.
Peb tuaj yeem pom rhamnose khi rau lwm cov suab thaj. Piv txwv li, nws tuaj yeem pom glycone feem ntawm glycosides los ntawm ntau cov nroj tsuag. Tsis tas li ntawd, rhamnose tuaj yeem pom los ua ib feem ntawm cov cell membrane ntawm cov kab mob acid-ceev ceev hauv cov genus ntawm Mycobacterium.
Qhov txawv ntawm Fucose thiab Rhamnose yog dab tsi?
Fucose thiab rhamnose qhia tib yam tshuaj mis tab sis cov qauv tshuaj sib txawv uas sawv cev sib txawv. Qhov sib txawv tseem ceeb ntawm fucose thiab rhamnose yog tias fucose yog ib qho aldohexose tam sim no nyob rau hauv ob peb glycans thiab mucopolysaccharides, whereas rhamnose yog ib tug methyl pentose uas tshwm sim nyob rau hauv nplooj thiab paj ntawm tshuaj lom ivy thiab kuj raws li ib tug constituent ntawm ntau cov nroj tsuag glycosides.
Hauv qab no yog cov ntsiab lus ntawm qhov sib txawv ntawm fucose thiab rhamnose hauv daim ntawv tabular rau kev sib piv ntawm ib sab.
Summary – Fucose vs Rhamnose
Qhov sib txawv tseem ceeb ntawm fucose thiab rhamnose yog tias fucose yog ib qho aldohexose tam sim no nyob rau hauv ntau glycans thiab mucopolysaccharides, whereas rhamnose yog ib tug methyl pentose uas tshwm sim nyob rau hauv nplooj thiab paj ntawm tshuaj lom ivy thiab kuj raws li ib tug constituent ntawm ntau cov nroj tsuag glycosides.
