Qhov txawv ntawm Brodifacoum thiab Bromadiolone yog dab tsi

2024 Tus sau: Alex Aldridge | [email protected]. Kawg hloov kho: 2023-12-17 13:40

Qhov txawv ntawm brodifacoum thiab bromadiolone yog tias brodifacoum muaj zog dua bromadiolone.

Ob leeg brodifacoum thiab bromadiolone yog cov tshuaj lom uas tuaj yeem ua tshuaj tua kab. Brodifacoum yog cov tshuaj lom neeg tuag hu ua 4-hydroxycoumarin vitamin K antagonist anticoagulant, whereas bromadiolone yog ib qho tshuaj tua kab mob muaj zog.

Brodifacoum yog dab tsi?

Brodifacoum yog tshuaj lom neeg tuag hu ua 4-hydroxycoumarin vitamin K antagonist anticoagulant. Cov tshuaj no tsis ntev los no tau los ua ib qho ntawm cov tshuaj tua kab ntau tshaj plaws hauv ntiaj teb. Feem ntau, cov tshuaj lom no muaj txiaj ntsig zoo li tshuaj tua kab mob. Txawm li cas los xij, nws kuj tseem siv tau los tswj cov kab tsuag loj dua, suav nrog possum. Txoj kev ntawm kev tswj hwm yog qhov ncauj, dermal, lossis nqus pa.

Daim duab 01: Cov Qauv Tshuaj ntawm Brodifacoum

Brodifacoum tshwj xeeb muaj lub neej ntev ib nrab ntawm lub cev. Ntxiv mus, nws ib nrab-lub neej tuaj yeem mus txog 9 lub hlis. Qhov no yuav tsum muaj kev kho mob ntev nrog cov tshuaj tua kab mob vitamin K rau tib neeg thiab tsiaj lom lub sijhawm. Tsis tas li ntawd, cov tshuaj no muaj kev pheej hmoo ntawm kev lom thib ob rau cov tsiaj nyeg thiab noog. Qhov tseem ceeb tshaj, muaj pov thawj tias qee cov neeg tau siv cov tshuaj lom no hauv lawv qhov kev sim tua tus kheej.

Cov tshuaj formula ntawm brodifacoum yog C₃₁H₂₃BrO_{3 Cov molar loj ntawm Cov tshuaj no yog 523.42 g / mol. Nws muaj qhov melting point ntawm 228 mus rau 230 degrees Celsius, nyob ntawm seb cov impurities. Tsis tas li ntawd, cov khoom no yog insoluble hauv dej. Bioavailability yog 100%, thiab nws cov metabolism hauv qeeb, tsis tiav, thiab feem ntau yog mob siab. Excretion feem ntau tshwm sim los ntawm cov quav maj mam.}

YBromadiolone yog dab tsi?

Bromadiolone yog ib qho tshuaj tua kab mob muaj zog. Nws tuaj yeem raug cais raws li tiam thib ob 4-hydroxycoumarin derivative thiab vitamin K antagonist. Feem ntau, cov tshuaj no hu ua super-warfarin. Qhov no yog vim nws ntxiv potency thiab nyiam mus sau nyob rau hauv lub siab ntawm cov kab mob lom.

Daim duab 02: Cov Qauv Tshuaj ntawm Bromadiolone

Cov tshuaj formula ntawm bromadiolone yog C₃₀H₂₃BrO_{4Nws cov molar loj yog li 527.414 g / mol. Cov tshuaj no tshwm sim raws li kev sib xyaw ntawm plaub stereoisomers. Muaj ob lub chaw stereoisomeric ntawm phenyl thiab hydrocyl hloov cov pa roj carbon atoms hauv cov saw hlau uas tshwm sim ntawm qhov hloov pauv ntawm txoj hauj lwm 3 ntawm coumarin.}

Thaum xav txog qhov muaj tshuaj lom ntawm cov khoom no, nws tau nqus los ntawm lub plab zom mov, lub ntsws, thiab kev sib cuag ntawm daim tawv nqaij. Txawm li cas los xij, cov tshuaj tua kab no tau muab rau ntawm qhov ncauj. Nws yog vitamin K antagonist; Yog li ntawd, qhov tsis muaj vitamin K hauv peb cov hlab ntsha tuaj yeem ua rau txo qis hauv cov ntshav txhaws, uas tuaj yeem ua rau tuag taus los ntawm cov hlab ntsha sab hauv.

Qhov txawv ntawm Brodifacoum thiab Bromadiolone yog dab tsi?

Ob leeg brodifacoum thiab bromadiolone yog cov tshuaj lom uas tuaj yeem ua tshuaj tua kab. Brodifacoum yog cov tshuaj lom neeg tuag hu ua 4-hydroxycoumarin vitamin K antagonist anticoagulant thaum bromadiolone yog cov tshuaj tua kab mob muaj zog. Qhov sib txawv tseem ceeb ntawm brodifacoum thiab bromadiolone yog tias brodifacoum muaj zog dua li bromadiolone. Tsis tas li ntawd, brodifacoum zoo nkaus li cov hmoov dawb dawb rau fawn-xim hmoov, thaum bromadiolone zoo li cov hmoov dawb dawb rau fawn-xim hmoov. Cov tshuaj formula ntawm brodifacoum yog C₃₁H₂₃BrO₃, hos cov tshuaj formula ntawm bromadiolone yog C. ₃₁H₂₃BrO₃

Cov hauv qab no infographic nthuav tawm qhov sib txawv ntawm brodifacoum thiab bromadiolone hauv daim ntawv tabular rau kev sib piv ntawm ib sab.

Summary – Brodifacoum vs Bromadiolone

Brodifacoum yog tshuaj lom neeg tuag hu ua 4-hydroxycoumarin vitamin K antagonist anticoagulant. Bromadiolone yog ib qho tshuaj tua kab mob uas muaj zog heev. Qhov sib txawv tseem ceeb ntawm brodifacoum thiab bromadiolone yog tias brodifacoum muaj zog dua li bromadiolone. Tsis tas li ntawd, brodifacoum zoo nkaus li cov hmoov dawb dawb rau cov hmoov xim av, thaum bromadiolone zoo nkaus li cov hmoov dawb dawb rau cov hmoov xim daj.