Qhov sib txawv tseem ceeb ntawm troponin thiab calmodulin yog tias troponin yog qhov nyuaj ntawm peb cov proteins pom nyob rau hauv cov leeg nqaij thiab pob txha, thaum calmodulin yog ib qho me me dumbbell zoo li cov protein pom nyob rau hauv cytoplasm ntawm tag nrho cov hlwb eukaryotic.
Troponin thiab calmodulin yog ob qho proteins. Troponin yog ib qho nyuaj ntawm peb cov proteins, thaum calmodulin yog ib qho protein me me uas ua los ntawm ob lub globular domains txuas nrog lub hauv paus alpha helix. Troponin yog qhov tseem ceeb hauv kev tswj hwm ntawm lub plawv thiab cov leeg pob txha. Hauv qhov sib piv, calmodulin tswj ntau cov txheej txheem ntawm tes.
Troponin yog dab tsi?
Troponin yog ib qho nyuaj ntawm peb txoj kev tswj hwm cov protein uas pom nyob rau hauv cov hlab plawv thiab cov leeg pob txha. Peb cov proteins sib txawv yog troponin T, troponin C thiab troponin I. Troponin proteins pab tswj cov hlab plawv thiab cov leeg pob txha. Troponin C zoo ib yam li calmodulin ob qho tib si hauv cov amino acid sib lawv liag thiab hauv peb-dimensional qauv. Zoo ib yam li calmodulin, troponin C muaj calcium-binding sites.
Daim duab 01: Troponin C
Feem ntau, troponin tam sim no muaj tsawg heev hauv peb cov ntshav thiab tsis tuaj yeem kuaj pom. Tus nqi ib txwm yog qis dua 0.04 ng / ml. Txawm li cas los xij, yog tias muaj me ntsis tab sis pom tau nce hauv qib troponin, nws qhia tias muaj kev pheej hmoo ntawm lub plawv puas. Qhov no yog vim hais tias thaum muaj kev puas tsuaj ntawm cov leeg plawv, nws tso troponin rau hauv cov hlab ntsha. Yog li ntawd, ib qho kev nce qib ntawm troponin yog qhov qhia tau tias muaj kev raug mob plawv.troponin qib siab tshaj 0.04 ng / ml qhia tias muaj mob plawv. Yog li, cov kws kho mob ua qhov kev sim troponin los ntsuas seb puas muaj kev puas tsuaj hauv lub plawv. Troponin test yog kuaj ntshav yooj yim, thiab nws ntsuas troponin T lossis troponin I proteins hauv cov ntshav.
Calmodulin yog dab tsi?
Calmodulin yog ib qho me me dumbbell-zoo li protein uas muaj nyob rau hauv cytoplasm ntawm tag nrho cov eukaryotic hlwb. Calmodulin yog ib qho protein ntau khaws cia. Nws yog ubiquitous nyob rau hauv tag nrho cov eukaryotic hlwb thiab paub zoo tshaj plaws rau nws muaj peev xwm mus qhib CaM-dependent kinases nyob rau hauv ntau yam cell. Nws yog tsim los ntawm ob lub globular domains txuas nrog lub hauv paus alpha helix. Txhua tus sau muaj peb alpha-helices thiab ob txhais tes calcium-binding EF. Qhov loj ntawm cov protein yog 16.7kDa.
Daim duab 02: Calmodulin
Lub luag haujlwm tseem ceeb ntawm calmodulin yog los kho Ca2+ nyob ntawm kev taw qhia. Yog li, nws kho kom haum rau kev tswj hwm ntawm ntau cov enzymes, ion channels, thiab lwm yam proteins los ntawm calcium. Ntxiv mus, nws tswj ntau lwm cov txheej txheem ntawm tes.
Dab tsi zoo sib xws ntawm Troponin thiab Calmodulin?
- Troponin thiab calmodulin yog cov proteins.
- Lawv ua tiav cov haujlwm tseem ceeb hauv peb lub cev.
- Calmodulin zoo ib yam li troponin C.
Qhov txawv ntawm Troponin thiab Calmodulin yog dab tsi?
Troponin yog cov protein uas muaj nyob hauv cov leeg nqaij thiab pob txha, thaum calmodulin yog cov protein uas muaj nyob hauv cytoplasm ntawm tag nrho cov hlwb eukaryotic. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm troponin thiab calmodulin. Raws li txoj cai, troponin yog ib qho nyuaj ntawm peb cov proteins, thaum calmodulin yog tsim los ntawm ob lub globular domains txuas nrog lub hauv paus alpha-helix.
Ntxiv mus, lwm qhov sib txawv tseem ceeb ntawm troponin thiab calmodulin yog lawv txoj haujlwm; troponin tswj cov contractions ntawm lub plawv thiab cov leeg pob txha thaum lub sij hawm calmodulin mediates Ca2+ -dependent signalling.
Hauv qab infographic qhia txog qhov sib txawv ntawm troponin thiab calmodulin.
Summary – Troponin vs Calmodulin
Troponin yog cov protein uas pom muaj nyob hauv cov pob txha thiab lub plawv cov leeg. Nws tswj cov leeg nqaij contraction. Troponin theem nyob rau hauv peb cov hlab ntsha yog undetectable. Thaum lub plawv cov leeg puas lawm, lawv tso troponin mus rau hauv cov ntshav yog li, cov qib troponin siab qhia tau tias yuav raug mob plawv. Nyob rau hauv sib piv, calmodulin yog ib tug me me dumbbell-zoo li tus protein nyob rau hauv tag nrho cov eukaryotic hlwb. Nws mediates calcium nyob signaling. Yog li, qhov no qhia txog qhov sib txawv ntawm troponin thiab calmodulin.
