Qhov sib txawv tseem ceeb ntawm endocytosis thiab receptor mediated endocytosis yog tias endocytosis yog ib lub xovtooj ntawm tes uas cov cell noj cov khoom hauv lub cell los ntawm kev tsim cov vesicles. Meanwhile, receptor-mediated endocytosis yog ib daim ntawv ntawm endocytosis uas receptors nyob rau ntawm lub xovtooj ntawm tes yog siv los ntes cov hom phiaj tshwj xeeb xws li metabolites, hormones, proteins, thiab lwm yam.
Endocytosis yog cov txheej txheem cellular uas pab coj cov tshuaj mus rau hauv lub cell los ntawm invagination ntawm nws daim nyias nyias los tsim ib lub vesicle. Phagocytosis, receptor-mediated endocytosis, thiab pinocytosis yog peb hom endocytosis. Pinocytosis yog kev noj cov kua rau hauv cov hlwb los ntawm budding ntawm me me vesicles los ntawm cell membrane. Receptor-mediated endocytosis yog txheej txheem uas nqus cov molecules tshwj xeeb thiab cov kab mob hauv lub cell, paub txog cov molecules los ntawm receptors nyob rau hauv cell membrane thiab tom qab ntawd los ntawm kev tsim cov hlwv me me los ntawm cov cell membrane. Phagocytosis noj cov khoom loj, xws li cov khib nyiab ntawm tes, cov kab mob xws li cov kab mob, cov hlwb tuag, cov plua plav, cov ntxhia me me, thiab lwm yam, rau hauv lub cell los ntawm kev tsim phagosomes.
YEndocytosis yog dab tsi?
Endocytosis yog ib qho txheej txheem ntawm tes uas pab coj cov tshuaj nkag mus rau sab hauv ntawm tes. Thaum cov ntaub ntawv tsim nyog tuaj txog ze ntawm lub plasma membrane, plasma membrane nyob ib puag ncig thiab sab hauv lawv. Tom qab ntawd nws buds tawm hauv lub cell, tsim ib lub vesicle uas muaj cov ntaub ntawv. Muaj peb hom endocytosis: phagocytosis, pinocytosis thiab receptor-mediated endocytosis.
Daim duab 01: Hom Endocytosis
Phagocytosis yog cov txheej txheem ntawm kev noj cov khoom loj xws li cov khib nyiab ntawm tes, cov kab mob xws li cov kab mob, cov hlwb tuag, cov plua plav, cov pob zeb me me, thiab lwm yam, rau hauv lub cell los ntawm kev tsim phagosomes. Feem ntau lub cev tiv thaiv kab mob, suav nrog cov ntaub so ntswg macrophages, neutrophils thiab monocytes yog cov kws tshaj lij phagocytic hlwb. Feem ntau, phagocytosis yog cov txheej txheem tiv thaiv uas rhuav tshem cov kab mob nkag los ntawm kev nkag mus rau hauv phagosomes thiab tom qab ntawd rhuav tshem lawv hauv lub cell. Ib qho kev ua lytic tshwm sim hauv lub xovtooj ntawm qhov chaw uas lysosome khi rau phagosome thiab tso tawm lytic enzymes los rhuav tshem cov kab mob los yog cov teeb meem los ntawm kev tsim cov phagolysosome.
Pinocytosis yog lwm hom endocytosis uas cov kua dej ntxiv hauv lub cell los ntawm kev tsim cov vesicles me. Cov molecules me me uas raug tshem tawm hauv cov kua dej ntxiv yog thauj los ntawm cov txheej txheem no. Pinocytosis tsis xaiv cov molecules los thauj. Txawm li cas los xij cov me me molecules tam sim no hauv dej tau noj los ntawm pinocytosis. Li no, nws tsis yog suav tias yog ib qho txheej txheem tshwj xeeb. Nws kuj tsis yog ib qho kev ua tau zoo. Txawm li cas los xij, pinocytosis tshwm sim hauv ntau lub hlwb. Qhov tseeb, pinocytosis yog qhov kev thauj mus los ntawm cov txheej txheem hauv daim siab hlwb, lub raum hlwb, cov hlwb capillary thiab cov hlwb epithelial.
Receptor-mediated endocytosis yog hom thib peb ntawm endocytosis, tau piav qhia nrog cov ntsiab lus hauv qab no.
Receptor-Mediated Endocytosis yog dab tsi?
Receptor-mediated endocytosis yog ib hom endocytosis uas macromolecules raug coj mus rau hauv lub cell xaiv los ntawm cov kua dej extracellular. Cov txheej txheem no yog kho los ntawm cov receptors nyob rau ntawm lub xovtooj ntawm tes thiab kev khi tshwj xeeb nrog cov macromolecules sab nraud ntawm tes. Receptors uas koom nrog receptor-mediated endocytosis concentrate nyob rau hauv clathrin-coated pits. Extracellular macromolecules khi nrog receptors thiab internalize rau hauv clathrin-coated vesicles tsim los ntawm clathrin-coated pits. Lub clathrin-coated vesicles ces fuse nrog thaum ntxov endosomes; Lawv cov ntsiab lus raug txheeb xyuas rau kev thauj mus rau lysosomes lossis rov ua dua mus rau plasma membrane.
Daim duab 02: Receptor-Mediated Endocytosis
Receptor-mediated endocytosis yog ib lub tswv yim tshwj xeeb rau kev noj cov molecules rau hauv cov hlwb, tsis zoo li pinocytosis. Cov khoom uas raug thauj mus rau hauv yog txiav txim siab los ntawm cov receptors tam sim no ntawm lub cell membrane nto. Tsis tas li ntawd, nws yog cov txheej txheem ua tau zoo dua li pinocytosis.
Dab tsi zoo sib xws ntawm Endocytosis thiab Receptor-Mediated Endocytosis?
- Receptor-mediated endocytosis yog ib hom kab mob endocytosis.
- Lawv yog cov txheej txheem ntawm tes.
- Ob lub tswv yim pab txhawb nqa cov khoom hauv lub cell.
- Cov txheej txheem no tsim cov membrane coated vesicles.
Qhov txawv ntawm Endocytosis thiab Receptor Mediated Endocytosis yog dab tsi?
Endocytosis yog ib lub xovtooj ntawm tes uas txav cov khoom mus rau hauv lub xovtooj los ntawm kev kaw lawv hauv cov vesicle ua los ntawm cov plasma membrane, thaum receptor-mediated endocytosis yog ib hom endocytosis kho los ntawm cov receptors nyob rau ntawm lub cell. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm endocytosis thiab receptor mediated endocytosis. Muaj peb hom endocytosis li phagocytosis, pinocytosis thiab receptor-mediated endocytosis, tab sis tsis muaj subtypes ntawm receptor-mediated endocytosis.
Ntxiv mus, endocytosis yuav siv cov tshuaj xaiv thiab tsis xaiv rau hauv lub cell, thaum receptor-mediated endocytosis yog qhov tshwj xeeb, thiab nws xaiv lub hom phiaj macromolecules nkag mus rau hauv lub cell. Yog li ntawd, qhov no lwm qhov sib txawv ntawm endocytosis thiab receptor mediated endocytosis.
Summary – Endocytosis vs Receptor-Mediated Endocytosis
Endocytosis yog ib qho kev thauj mus los uas ua rau cov khoom nkag mus rau hauv lub xovtooj ntawm tes los ntawm kev kaw lawv hauv lub vesicle ua los ntawm cov plasma membrane. Muaj peb hom endocytosis. Ntawm lawv, receptor-mediated endocytosis yog ib daim ntawv, thiab nws yog ua los ntawm cov receptors tam sim no ntawm lub xov tooj ntawm tes. Yog li nws txawv ntawm ob hom endocytosis. Phagocytosis thiab pinocytosis yog ob hom endocytosis. Yog li, qhov no qhia txog qhov sib txawv ntawm endocytosis thiab receptor mediated endocytosis.
