Qhov Tseem Ceeb Qhov txawv - Pegasys vs Pegintron
Raws li kev txhim kho ntawm biotechnology hauv kev lag luam kws tshuaj, ntau hom tshuaj tau tsim nrog lub hom phiaj ntawm kev kho mob sib txawv ntawm cov kab mob tuag taus nrog tsawg dua cov kev mob tshwm sim. Pegasys uas los ua lub npe ntawm Peginterferon Alfa 2A, yog ib qho tshuaj uas tsim los rau kev kho kab mob siab. Pegintron yog lub npe hu ua Peginterferon Alfa 2B uas yog tsim los kho mob qog noj ntshav (melanoma) thiab kab mob siab. Pegasys yog siv rau kev kho kab mob siab B thiab C thaum, Pegintron yog siv rau kev kho mob ntawm melanoma thiab kab mob siab C tshwj tsis yog rau kab mob siab B. Qhov no yog qhov sib txawv tseem ceeb ntawm Pegasys thiab Pegintron.
Pegasys yog dab tsi?
Nyob rau hauv cov ntsiab lus ntawm kws tshuaj, Pegasys yog ib yam tshuaj uas yog siv los kho kab mob siab B thiab kab mob siab C. Nws tseem hu ua Peginterferon alpha-2a. Pegasys yog lub npe ntawm Peginterferon alpha-2a. Nws yog ib qho tshuaj uas belongs rau tsev neeg interferon. Interferons yog cov proteins uas tau tso tawm los ntawm lub cev tiv thaiv kab mob thaum muaj kab mob los ntawm cov kab mob. Nws kuj koom nrog kev tswj hwm ntawm lub cev tiv thaiv kab mob thaum kis kab mob. Pegasys hu ua Pegylated interferon alpha 2a thiab. Cov tshuaj yog pegylated uas tiv thaiv kev tawg ntawm cov tshuaj. Ib qho chaw ntawm nws tuaj yeem raug pegylated los ntawm covalent lossis noncovalent bonding ntawm polyethylene glycol.
Thaum cov txheej txheem kho kab mob siab C, Pegasys tau muab los ua kev sib xyaw ua ke nrog Ribavirin txhawm rau txhawb nws cov teebmeem. Tab sis Ribavirin tsis siv thaum kho cov poj niam cev xeeb tub. Cov txheej txheem kho kab mob siab B yog qhov sib txawv ntawm tus kab mob siab C. Hauv kab mob siab B, Pegasys yog muab rau ib leeg, tsis yog tshuaj ua ke. Cov tshuaj yog txhaj rau hauv qab ntawm daim tawv nqaij thaum lub sij hawm ob txoj kev kho mob.
Hauv Tebchaws Meskas, kev siv tshuaj kho mob ntawm Pegasys tau pom zoo xyoo 2001 los ntawm World He alth Organization ua tshuaj muaj kev nyab xeeb. Nws yog siv thoob ntiaj teb rau kev kho mob ntawm tus kab mob siab C uas tau kuaj pom hauv cov tib neeg uas muaj kab mob HIV lossis mob cirrhosis. Pegasys kuj muaj ntau yam kev phiv. Cov kev mob tshwm sim tuaj yeem tshwm sim nyob rau hauv cov mob me me xws li mob taub hau, xeev siab, qaug zog lossis nws tuaj yeem ua rau muaj kev phom sij txaus ntshai xws li kev puas siab puas ntsws, autoimmune disorders, nquag tshwm sim ntawm kev kis kab mob thiab ntshav txhaws.
Pegintron yog dab tsi?
Pegintron yog ib yam tshuaj uas siv los kho kab mob siab C thiab Melanoma. Melanoma feem ntau hu ua kab mob qog nqaij hlav ntawm daim tawv nqaij qhov chaw ntawm cov qog nqaij hlav ntawm cov melanocytes uas koom nrog hauv kev tsim cov melanin. Peginterferon alpha-2b yog lub npe hu ua Peginterferon alpha-2b. Cov tshuaj belongs rau tsev neeg interferon. Txij li thaum nws yog ib qho interferon, nws ua tau zoo thaum lub sij hawm kis kab mob uas tsim nyob rau hauv intracellular tej yam kev mob uas cuam tshuam lub cev tsis muaj zog. Pegintron koom nrog hauv kev tswj hwm kev tiv thaiv kab mob. Cov tshuaj no tseem hu ua Pegylated alpha 2b txij thaum cov tshuaj yog pegylated; bonded rau polyethylene glycol los ntawm covalent thiab noncovalent bonds. Qhov no tiv thaiv kev tawg ntawm cov tshuaj.
Thaum kho tus kab mob siab C, pegintron tau muab rau cov neeg mob ua ke nrog Ribavirin. Qhov kev sib xyaw ua ke no tau ua pov thawj tias muaj txiaj ntsig zoo hauv kab mob siab C ntau dua li muab pegintron ib leeg. Tab sis qhov no txawv ntawm kev kho mob ntawm melanoma. Thaum kho melanoma, pegintron yog muab los ua ib qho tshuaj.
Daim duab 02: Melanoma
Pegintron ua rau muaj kev phiv me me xws li xeev siab, mob ntawm qhov chaw txhaj tshuaj, ua npaws thiab plaub hau poob. Cov tsos mob tuaj yeem tshwm sim rau cov neeg mob tuag taus xws li kev puas siab puas ntsws, thrombosis (tsim cov ntshav txhaws) thiab teeb meem hauv siab. Nws kuj tseem tuaj yeem ua rau lub plawv dhia tsis zoo. Pegintron tshuaj siv JAK-STAT teeb liab txoj hauv kev raws li nws cov txheej txheem ntawm kev ua. Qhov no ua rau cov txheej txheem cell tuag thiab apoptosis nyob rau theem kawg. Pegintron muaj peev xwm sau tau ntau lub noob thiab tsim kom muaj ntau yam kev tiv thaiv kab mob cytokine. Cov cytokine no ua rau kev txhim kho ntawm hom II T pab hlwb uas txhim kho cov tshuaj tiv thaiv kab mob los ntawm B hlwb.
Dab tsi zoo sib xws ntawm Pegasys thiab Pegintron?
- Ob leeg yog cov tshuaj uas feem ntau siv los kho kab mob siab nrog ribavirin.
- Ob leeg tuaj yeem ua rau mob me me xws li qaug zog, xeev siab thiab mob taub hau thiab ua rau muaj kev phom sij txaus ntshai xws li mob hlwb thiab thrombosis.
Qhov txawv ntawm Pegasys thiab Pegintron yog dab tsi?
Pegasys vs Pegintron |
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| Pegasys yog ib yam tshuaj uas siv los kho tus kab mob siab B thiab kab mob siab C. | Pegintron yog ib yam tshuaj uas siv los kho kab mob siab C thiab melanoma. |
| Kev mob tshwm sim tuag taus | |
| Kev tsis haum tshuaj tiv thaiv kab mob | Lub plawv dhia tsis zoo |
| Peginterferon Alfa 2A, Pegylated Alfa 2A | Peginterferon Alfa 2B, Pegylated Alfa 2B |
Summary – Pegasys vs Pegintron
Thaum kho kab mob siab C thiab kab mob siab B, Pegasys tau siv. Pegasys yog lub npe nrov ntawm Peginterferon Alfa 2A. Kab mob siab C yog kho raws li kev kho mob ua ke nrog Peginterferon Alfa 2A thiab Ribavirin. Pegasys yog muab los ua ib qho tshuaj thaum kho kab mob siab B. Pegintron yog lub npe ntawm Peginterferon Alfa 2B. Nws yog siv los kho kab mob siab B thiab melanoma. Ob qho tshuaj yog pegylated txhawm rau tiv thaiv kev tawg. Pegintron kuj tseem ua ke nrog ribavirin thaum kho kab mob siab C thiab muab ua ib qho tshuaj rau melanoma. Pegasys thiab Pegintron muaj cov kev mob tshwm sim zoo sib xws xws li kub taub hau, xeev siab, mob taub hau, thrombosis, thiab kev puas siab puas ntsws. Qhov no tuaj yeem qhia tau tias qhov txawv ntawm Pegasys thiab Pegintron.
Download the PDF Version of Pegasys vs Pegintron
Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline hom phiaj raws li daim ntawv ceeb toom. Thov download PDF version ntawm no Qhov txawv nruab nrab ntawm Pegasys thiab Pegintron
