Qhov sib txawv tseem ceeb ntawm ferritin thiab hemosiderin yog tias ferritin yog ib qho protein nyob hauv cellular uas khaws cov hlau thiab tso tawm hauv kev tswj hwm, thaum hemosiderin yog ib qho chaw cia hlau uas yog tsim los ntawm qee qhov zom ferritin thiab lysosomes.
Hlau khaws cia hauv tib neeg lub siab hauv ob hom: ferritin thiab hemosiderin. Ferritin yog ib qho protein uas muaj peev xwm khaws cia txog 4500 hlau (III) ions ib qho protein molecule. Yog tias lub peev xwm no dhau mus, ib qho nyuaj ntawm cov ntaub ntawv hlau nrog phosphate thiab hydroxide, thiab nws yog hu ua hemosiderin.
Ferritin yog dab tsi?
Ferritin yog ib qho protein ntau hauv cellular uas khaws cov hlau thiab tso tawm hauv kev tswj hwm. Nws yog universal intracellular protein. Cov protein no yog tsim los ntawm yuav luag txhua yam kab mob nyob, suav nrog archaea, kab mob, algae, cov nroj tsuag siab dua, thiab tsiaj txhu. Yog li ntawd, nws yog thawj intracellular hlau cia protein ua hauj lwm nyob rau hauv ob qho tib si prokaryotes thiab eukaryotes. Nws feem ntau khaws cov hlau nyob rau hauv daim ntawv soluble thiab tsis muaj tshuaj lom rau tib neeg. Nws kuj ua raws li qhov tsis txaus tiv thaiv cov hlau tsis txaus thiab cov hlau ntau dhau.
Daim duab 01: Ferritin
Feem ntau, ferritin pom raws li cov protein cytosolic hauv cov ntaub so ntswg. Txawm li cas los xij, me me ntawm ferritin tuaj yeem tso rau hauv cov ntshav thiab. Serum ferritin ua haujlwm ua cov khoom siv hlau. Ntxiv mus, plasma ferritin yog ib qho cim qhia tsis ncaj ntawm tag nrho cov nyiaj ntawm cov hlau khaws cia hauv tib neeg lub cev. Yog li ntawd, plasma ferritin yog siv los ua ib qho kev qhia tsis ncaj rau cov hlau tsis muaj peev xwm anemia. Hom kev sim no hu ua ferritin test. Tsis tas li ntawd, ferritin yog globular protein. Nws yog ib tug complex protein uas muaj 24 protein subunits. Ntau qhov kev sib tshuam ntawm cov hlau-protein tuaj yeem pom hauv cov qauv. Lub ferritin molecule uas tsis ua ke nrog hlau yog hu ua apoferritin.
Hemosiderin yog dab tsi?
Hemosiderin yog ib qho chaw cia hlau uas muaj ib nrab zom cov ferritin thiab lysosomes. Kev puas tsuaj ntawm heme ntawm hemoglobin ua rau nce mus rau biliverdin thiab hlau. Tom qab ntawd, lub cev ntxiab thiab khaws cov hlau tso tawm hauv daim ntawv ntawm hemosiderin hauv cov ntaub so ntswg. Ntxiv mus, hemosiderin kuj tsim vim txoj kev txawv txav ntawm ferritin. Hemosiderin tsuas yog pom nyob rau hauv cov hlwb. Nws tshwm sim raws li ib tug complex ntawm ferritin, denatured ferritin, thiab lwm yam ntaub ntawv nyob rau hauv cov hlwb. Feem ntau, cov hlau tso rau hauv hemosiderin tsis muaj peev xwm muab hlau thaum xav tau.
Daim duab 02: Hemosiderin
Ntau dhau ntawm hemosiderin feem ntau kuaj pom hauv cov hlwb ntawm mononuclear phagocyte system (MPS) lossis qee zaus hauv cov hlwb epithelial ntawm daim siab thiab lub raum. Tsis tas li ntawd, hemosiderin feem ntau pom muaj nyob rau hauv macrophages thiab muaj ntau nyob rau hauv cov xwm txheej tom qab hemorrhage. Yog li ntawd, ntau dhau ntawm hemosiderin tuaj yeem pom nyob rau hauv ntau yam kab mob xws li mob cell anemia thiab thalassemia.
Dab tsi yog qhov zoo sib xws ntawm Ferritin thiab Hemosiderin?
- Ferritin thiab hemosiderin yog ob hom hlau khaws cia feem ntau hauv tib neeg lub siab.
- Ob daim ntawv tuaj yeem pom hauv lub hlwb.
- Qhov tseeb, lawv feem ntau pom nyob rau hauv daim siab hlwb.
- Hemosiderin tuaj yeem tsim vim txoj kev txawv txav ntawm ferritin.
- Lawv ua lub luag haujlwm tseem ceeb hauv cov hlau homeostasis hauv lub cev.
Qhov txawv ntawm Ferritin thiab Hemosiderin yog dab tsi?
Ferritin yog ib qho protein ntau hauv cov cell uas khaws cov hlau thiab tso tawm hauv kev tswj hwm, thaum hemosiderin yog ib qho chaw cia hlau uas tsim los ntawm qee qhov zom ferritin thiab lysosomes. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm ferritin thiab hemosiderin. Tsis tas li ntawd, ferritin pom ob qho tib si hauv hlwb thiab hauv cov ntshav ntshav, thaum hemosiderin tsuas pom nyob hauv cov hlwb.
Cov ntawv qhia hauv qab no nthuav tawm qhov sib txawv ntawm ferritin thiab hemosiderin hauv daim ntawv teev npe rau kev sib piv ntawm ib sab.
Summary – Ferritin vs Hemosiderin
Ferritin thiab hemosiderin yog ob lub cev sib txuas, uas yog ob hom hlau khaws cia feem ntau hauv tib neeg lub siab. Ob daim ntawv tuaj yeem pom hauv cov hlwb. Ferritin yog ib qho intracellular protein uas khaws cov hlau thiab tso tawm raws li kev tswj hwm, thaum hemosiderin yog ib qho chaw cia hlau uas yog tsim los ntawm qee qhov zom cov ferritin thiab lysosomes. Hlau khaws cia hauv ferritin tau yooj yim muaj thaum lub cev xav tau. Hauv qhov sib piv, hlau khaws cia hauv hemosiderin tsis zoo thaum lub cev xav tau. Yog li, qhov no qhia txog qhov sib txawv ntawm ferritin thiab hemosiderin.
