Qhov sib txawv tseem ceeb ntawm cov lymphokines thiab cytokines yog tias cov lymphokines yog ib qho ntawm cov xov tooj ntawm tes taw qhia cytokine proteins uas tsim los ntawm T lymphocytes thaum cytokines yog ib qho dav thiab xoob ntawm cov xov tooj ntawm tes taw qhia cov proteins uas tsim los ntawm ntau lub hlwb. suav nrog macrophages, B lymphocytes, T lymphocytes, mast cells, endothelial cells, fibroblasts, thiab stromal cells.
Cell signaling, hu ua kev sib txuas lus ntawm tes, yog lub peev xwm ntawm lub xov tooj ntawm tes tau txais, txheej txheem, thiab xa cov teeb liab hauv nws qhov chaw sab nraud thiab hauv lub xov tooj ntawm tes. Lymphokines thiab cytokines yog ob hom proteins tseem ceeb hauv cell signaling. Lawv txoj kev koom tes hauv xov tooj ntawm tes yog ib feem tseem ceeb ntawm tib neeg lub cev kev cai. Ntxiv mus, lawv ua lub luag haujlwm tseem ceeb hauv tib neeg lub cev tiv thaiv kab mob ib yam nkaus.
Lymphokines yog dab tsi?
Lymphokines yog ib feem ntawm cov xov tooj ntawm tes taw qhia cytokine proteins uas tsim los ntawm T hlwb (lymphocytes). Lawv yog cov neeg nruab nrab ntawm cov protein uas coj lub cev tiv thaiv kab mob los ntawm kev taw qhia ntawm cov hlwb hauv lub cev. Lymphokines ua si ntau lub luag haujlwm tseem ceeb, suav nrog kev nyiam ntawm lwm lub cev tiv thaiv kab mob xws li macrophages thiab lwm yam lymphocytes mus rau qhov chaw muaj tus kab mob thiab lawv qhov kev ua haujlwm tom ntej txhawm rau npaj lawv los txhim kho lub cev tiv thaiv kab mob. Ntxiv rau qhov ntawd, lymphokines kuj pab B hlwb hauv kev tsim cov tshuaj tiv thaiv. Qhov no tsim cov tshuaj tiv thaiv tiv thaiv kab mob invading.
Qhov tseem ceeb tshaj, cov lymphocytes ncig tuaj yeem kuaj pom qhov me me ntawm lymphokines hauv cov hlab ntsha. Tom qab ntawd lawv txav mus rau qhov concentration ntawm lymphokines thaum xav tau kev tiv thaiv kab mob. Cov lymphokines tseem ceeb uas zais los ntawm CD4+ lossis T pab hlwb suav nrog interleukin 2, interleukin 3, interleukin 4, interleukin 5, interleukin 6, granulocyte-macrophage colony-stimulating factor, thiab interferon- gamma. B lymphocytes kuj muaj peev xwm tsim cov lymphokines.
Cytokines yog dab tsi?
Cytokines yog ib qho dav thiab xoob ntawm cov proteins me uas yog peptides. Lawv loj yog nyob ib ncig ntawm 5 mus rau 25 kDa. Cytokines tseem ceeb heev hauv cell signaling. Cytokines tsis tuaj yeem hla lub lipid bilayer ntawm cov hlwb kom nkag mus rau cytoplasm. Lub luag haujlwm ntawm cytokines suav nrog autocrine, paracrine, thiab endocrine cell signaling raws li immunomodulating agents. Txawm li cas los xij, cytokines txawv ntawm cov tshuaj hormones. Ntau hom cytokines muaj xws li chemokines, interferons, interleukins, lymphokines, thiab qog necrosis yam. Tab sis cov tshuaj hormones thiab kev loj hlob tsis suav nrog hauv pawg no.
Daim duab 01: Cytokines
Cytokines feem ntau yog tsim los ntawm ntau lub hlwb, suav nrog macrophages, B lymphocytes, T lymphocytes, mast cells, endothelial cells, fibroblasts, thiab stromal cells. Ntxiv mus, ib qho cytokine tej zaum yuav tsim los ntawm ntau tshaj ib hom ntawm tes. Tsis tas li ntawd, cytokines modulate qhov sib npaug ntawm kev humoral thiab cell-based tiv thaiv kab mob. Lawv kuj tswj cov kev loj hlob, kev loj hlob, thiab kev ua haujlwm ntawm ib tus neeg ntawm tes. Qee cov cytokines koom nrog hauv kev txhim kho lossis inhibiting kev ua ntawm lwm cov cytokines. Cytokines tseem ceeb heev hauv cov tswv teb cov lus teb rau kev kis kab mob, mob, raug mob, sepsis, mob qog noj ntshav, thiab kev yug me nyuam ib yam nkaus.
Dab tsi yog qhov zoo sib xws ntawm Lymphokines thiab Cytokines?
- Lymphokines thiab cytokines yog ob hom proteins tseem ceeb hauv kev taw qhia ntawm tes.
- Lawv kev koom tes hauv xovtooj ntawm tes yog ib feem tseem ceeb ntawm tib neeg lub cev kev cai.
- Ob leeg ua lub luag haujlwm tseem ceeb hauv tib neeg lub cev tiv thaiv kab mob thiab tiv thaiv tib neeg tiv thaiv kab mob invading thiab.
- Ob leeg sib txawv ntawm cov tshuaj hormones lossis kev loj hlob.
- Lawv yog cov molecules me heev.
- Lawv yog tsim los ntawm ntau hom hlwb.
Qhov txawv ntawm Lymphokines thiab Cytokines yog dab tsi?
Lymphokines yog ib qho ntawm cov xov tooj ntawm tes taw qhia cytokine cov proteins uas tsim los ntawm T hlwb, thaum cytokines yog ib qho dav thiab xoob pawg ntawm cov xov tooj ntawm tes me me uas tsim los ntawm ntau lub hlwb, suav nrog macrophages, B lymphocytes, T lymphocytes, mast. cell, endothelial hlwb, fibroblasts, thiab stromal hlwb. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm lymphokines thiab cytokines. Tsis tas li ntawd, qhov loj ntawm lymphokines nyob nruab nrab ntawm 10 txog 12 kDa, thaum qhov loj ntawm cytokines nyob nruab nrab ntawm 5 txog 25 kDa.
Cov ntawv qhia hauv qab no nthuav tawm qhov sib txawv ntawm lymphokines thiab cytokines hauv daim ntawv tabular rau kev sib piv ntawm ib sab.
Summary – Lymphokines vs Cytokines
Lymphokines thiab cytokines yog ob hom proteins uas tseem ceeb hauv kev taw qhia ntawm tes. Lawv yog cov tseem ceeb heev nyob rau hauv tus tswv teb cov lus teb rau kab mob, o, raug mob, sepsis, cancer, thiab kev loj hlob. Lymphokines yog ib feem ntawm cov xov tooj ntawm tes taw qhia cytokine proteins feem ntau tsim los ntawm T lymphocytes. Cytokines yog ib pawg dav thiab xoob ntawm cov xovtooj ntawm tes me me uas tsim los ntawm ntau lub hlwb, suav nrog macrophages, B lymphocytes, T lymphocytes, mast cells, endothelial cells, fibroblasts, thiab stromal cells. Yog li, qhov no qhia txog qhov sib txawv ntawm lymphokines thiab cytokines.
