Qhov sib txawv tseem ceeb ntawm acetylation thiab acylation yog tias acetylation koom nrog kev qhia ntawm pawg acetyl rau cov organic compound, whereas acylation koom nrog kev taw qhia ntawm pawg acyl rau cov organic compound.
Acetylation thiab acylation yog qhov tseem ceeb ntawm cov organic synthesis tshuaj. Acetylation yog cov tshuaj tiv thaiv esterification ntawm cov organic, thaum acylation yog ib qho kev hloov pauv ntawm electrophilic aromatic.
Acetylation yog dab tsi?
Acetylation yog cov txheej txheem tseem ceeb ntawm cov tshuaj organic uas koom nrog kev qhia txog pawg acetyl rau ib lub molecule. Nyob rau hauv cov txheej txheem no, "Ac" txhais tau hais tias ib pawg acetyl, thiab nws muaj cov tshuaj formula -C (O) CH3 nyob rau hauv uas cov pa atom yog sib txuas rau cov pa roj carbon atom ntawm ob daim ntawv cog lus, thiab ib pawg methyl txuas nrog cov pa roj carbon atom.. Qhov no yog ib qho kev hloov pauv. Nws tseem yog lub npe hu ua kev hloov pauv cov tshuaj tiv thaiv vim tias, hauv cov tshuaj tiv thaiv no, pawg acetyl hloov cov pab pawg ua haujlwm uas twb muaj nyob hauv cov molecule.
Feem ntau, acetyl pawg tuaj yeem hloov cov reactive hydrogen atoms nyob rau hauv cov molecules. Piv txwv li, hydrogen nyob rau hauv -OH pawg yog reactive hydrogen. Nws kuj tseem tuaj yeem hloov cov hydrogen atom nrog ib pawg acetyl. Qhov kev hloov no ua rau tsim cov ester. Qhov ntawd yog vim qhov kev hloov pauv no ua rau -O-C(O)-O daim ntawv cog lus.
Daim duab 01: Acetylation ntawm Salicylic Acid los ua Aspirin
Acetylation feem ntau tshwm sim hauv cov proteins. Cov txheej txheem no hu ua protein acetylation. Ntawm no, N-terminal acetylation tshwm sim los ntawm kev hloov cov hydrogen atom ntawm -NH2 pawg ntawm cov protein nrog ib pawg acetyl. Nws yog cov tshuaj tiv thaiv enzymatic vim enzymes catalyze nws.
Acylation yog dab tsi?
Acylation yog cov txheej txheem tshuaj lom neeg uas koom nrog kev sib ntxiv ntawm pawg acyl rau cov tshuaj lom neeg. Hauv cov txheej txheem no, peb muab lub npe sib txuas uas muab cov acyl pawg ua tus neeg sawv cev acylating. Ib pawg acyl muaj cov tshuaj formula R-C(=O)- qhov twg R yog ib qho aryl lossis ib pawg alkyl. Raws li cov khoom kawg ntawm acylation, muaj ob txoj kev acylation loj li O acylation thiab N acylation.
Daim duab 02: Acylation ntawm Benzene nyob rau hauv lub xub ntiag ntawm Ethanoyl Chloride
O acylation yog ib hom txheej txheem acylation uas cov khoom kawg muaj cov pa atom txuas cov acyl pawg rau cov reactant compound. Hauv lwm lo lus, muaj oxygen atom nruab nrab ntawm pawg acyl thiab cov reactant compound lub moiety. O acylation yog ib hom nucleophilic acyl hloov cov tshuaj tiv thaiv.
N acylation yog ib hom acylation uas cov khoom kawg muaj nitrogen atom, txuas cov acyl pawg rau cov reactant compound. Hauv lwm lo lus, muaj nitrogen atom ntawm pawg acyl thiab cov reactant compound lub moiety.
Qhov txawv ntawm Acetylation thiab Acylation yog dab tsi?
Acetylation thiab acylation yog qhov tseem ceeb ntawm cov organic synthesis tshuaj. Qhov sib txawv tseem ceeb ntawm acetylation thiab acylation yog tias acetylation cuam tshuam nrog kev qhia ntawm ib pawg acetyl rau cov organic compound, whereas acylation koom nrog kev taw qhia ntawm pawg acyl rau cov organic compound. Ntxiv mus, acetylation yog cov organic esterification cov tshuaj tiv thaiv, tab sis acylation yog ib qho kev hloov pauv ntawm electrophilic aromatic.
Cov hauv qab no infographic nthuav tawm qhov sib txawv ntawm acetylation thiab acylation hauv daim ntawv tabular rau ib sab ntawm kev sib piv.
Summary – Acetylation vs Acylation
Hauv luv luv, acetylation thiab acylation yog qhov tseem ceeb ntawm cov organic synthesis. Txawm li cas los xij, qhov sib txawv tseem ceeb ntawm acetylation thiab acylation yog tias acetylation koom nrog kev qhia ntawm ib pawg acetyl rau cov organic compound, whereas acylation koom nrog kev taw qhia ntawm ib pawg acyl rau cov organic compound.
