Qhov sib txawv tseem ceeb ntawm O acylation thiab N acylation yog tias O acylation tsim cov khoom kawg uas muaj cov pa oxygen whereas N acylation tsim cov khoom kawg uas muaj nitrogen.
Acylation yog cov txheej txheem tshuaj ntxiv ib pawg acyl rau cov tshuaj lom neeg. Nyob rau hauv cov txheej txheem no, cov compound uas muab cov acyl pawg hu ua acylating tus neeg sawv cev. Ib pawg acyl muaj cov tshuaj formula R-C(=O)- qhov twg R yog ib qho aryl lossis ib pawg alkyl. Raws li cov khoom kawg ntawm acylation, muaj peb txoj kev acylation loj xws li C acylation, O acylation thiab N acylation. Kab lus no tham txog O acylation thiab N acylation cov tshuaj tiv thaiv.
O Acylation yog dab tsi?
O acylation yog ib hom txheej txheem acylation uas cov khoom kawg muaj cov pa atom txuas cov acyl pawg rau cov reactant compound. Hauv lwm lo lus, muaj oxygen atom nruab nrab ntawm pawg acyl thiab cov reactant compound lub moiety. O acylation yog ib hom nucleophilic acyl hloov cov tshuaj tiv thaiv. Rau cov txheej txheem no, tus neeg sawv cev acylating feem ntau yog acyl chloride lossis acyl anhydride. Hom acylation no tshwm sim nrog cov reactant molecules uas muaj -OH pawg xws li aryl lossis alkyl alcohols.
Daim duab 01: Tus Txheej Txheem Kev Ua Haujlwm Zoo
N Acylation yog dab tsi?
N acylation yog ib hom acylation uas cov khoom kawg muaj nitrogen atom, txuas cov acyl pawg rau cov reactant compound. Hauv lwm lo lus, muaj nitrogen atom ntawm pawg acyl thiab cov reactant compound lub moiety.
Daim duab 02: Mechanism ntawm N Acylation Reaction
N acylation yog ib hom electrophilic acylation substation cov tshuaj tiv thaiv. Rau cov txheej txheem no, tus neeg sawv cev acylating feem ntau yog acyl chloride lossis acyl anhydride. Hom kev tshwm sim no tshwm sim nrog cov reactant molecules uas muaj -NH pawg xws li aniline. Piv txwv li, N acylation ntawm aniline yog ib txoj hauv kev zoo thaum acetic anhydride siv los ua tus neeg sawv cev acylating.
Qhov txawv ntawm O Acylation thiab N Acylation yog dab tsi?
Raws li cov khoom kawg ntawm cov txheej txheem acylation, muaj peb txoj kev acylation loj xws li C acylation, O acylation thiab N acylation. O acylation yog ib hom txheej txheem acylation uas cov khoom kawg muaj cov pa atom, txuas cov acyl pawg rau cov reactant compound, thaum N acylation yog ib hom acylation uas cov khoom kawg muaj nitrogen atom, txuas cov acyl pab pawg neeg. cov reactant compound.
Yog li ntawd, qhov sib txawv tseem ceeb ntawm O acylation thiab N acylation yog tias O acylation tsim cov khoom kawg uas muaj cov pa oxygen thaum N acylation tsim cov khoom kawg uas muaj nitrogen. Cov reactants uas dhau O acylation cov tshuaj tiv thaiv yog -OH pab pawg muaj cov tshuaj xws li phenols. Cov reactants uas tau txais N acylation yog cov tebchaw uas muaj -NH pawg xws li aniline. Ntxiv mus, O acylation yog ib hom nucleophilic acyl hloov cov tshuaj tiv thaiv thaum N acylation yog ib hom electrophilic acylation substation cov tshuaj tiv thaiv.
Cov infographic hauv qab no qhia txog qhov sib txawv ntawm O acylation thiab N acylation hauv daim ntawv teev npe.
Summary – O Acylation vs N Acylation
Raws li cov khoom kawg ntawm cov txheej txheem acylation, muaj peb txoj kev acylation loj xws li C acylation, O acylation thiab N acylation. Qhov sib txawv tseem ceeb ntawm O acylation thiab N acylation yog tias O acylation tsim cov khoom kawg uas muaj cov pa oxygen thaum N acylation tsim cov khoom kawg uas muaj nitrogen.
