Qhov sib txawv tseem ceeb ntawm bifonazole thiab clotrimazole yog lawv cov txiaj ntsig. Bifonazole tsis tshua muaj txiaj ntsig piv rau clotrimazole.
Bifonazole thiab clotrimazole yog ob yam tshuaj tiv thaiv kab mob. Bifonazole yog ib qho tshuaj uas poob rau hauv chav kawm ntawm imidazole antifungal tshuaj. Clotrimazole yog ib qho tshuaj tua kab mob uas muaj muag hauv lub npe lag luam Lotrimin.
YBifonazole yog dab tsi?
Bifonazole yog ib yam tshuaj uas los hauv chav kawm ntawm imidazole tshuaj tiv thaiv kab mob. Lub npe lag luam ntawm cov tshuaj no yog Canespor. Cov tshuaj no yog siv nyob rau hauv daim ntawv ntawm cov tshuaj pleev. Cov patent rau cov tshuaj no tau txais nyob rau hauv 1974, thiab nws tau pom zoo rau kev kho mob nyob rau hauv 1983. Tsis tas li ntawd, muaj kev sib txuas ntawm cov tshuaj no nrog carbamide thaum kho onychomycosis.
Daim duab 01: Cov Qauv Tshuaj ntawm Bifonazole
Bifonazole yog siv rau cov kab mob fungal xws li khaus khaus, ringworm, fungal ntawm daim tawv nqaij thiab kab mob poov xab. Txoj kev ntawm kev tswj hwm ntawm bifonazole yog tshuaj pleev ib ce. Nws yog kev lag luam muaj nyob hauv khw muag tshuaj. Cov tshuaj formula ntawm bifonazole yog C22H18N2.
Yuav muaj qee qhov kev mob tshwm sim ntawm kev siv cov tshuaj no, suav nrog qhov kub hnyiab thaum siv rau ntawm daim tawv nqaij, khaus, eczema, tawv nqaij qhuav, thiab lwm yam. Peb tuaj yeem txheeb xyuas cov tshuaj no ua cov tshuaj tsw qab muaj zog hauv vitro.
Bifonazole muaj ob hom kev ua. Ua ntej, nws tuaj yeem cuam tshuam cov fungal ergosterol biosynthesis ntawm ob lub ntsiab lus tshwj xeeb: kev hloov pauv ntawm 24-methylendihydrolanosterl rau desmethylsterol thiab inhibition ntawm HMG-CoA. Ob txoj hauv kev no tuaj yeem ua kom muaj cov kab mob fungicidal. Qhov kev txiav txim no feem ntau yog tawm tsam dermatophytes. Peb tuaj yeem paub qhov txawv ntawm cov tshuaj no los ntawm lwm cov tshuaj tiv thaiv kab mob nyob ntawm seb hom kev ua haujlwm tshwj xeeb no.
YClotrimazole yog dab tsi?
Clotrimazole yog tshuaj tua kab mob uas muaj muag hauv lub npe lag luam Lotrimin. Peb tuaj yeem siv cov tshuaj no los kho cov kab mob hauv qhov chaw mos, qhov ncauj qhov ncauj, pob khaus, pityriasis versicolor, thiab ntau hom kab mob ringworm, nrog rau cov kis las ko taw thiab khaus khaus. Tsis tas li ntawd, peb tuaj yeem noj nws qhov ncauj, lossis peb tuaj yeem siv rau ntawm daim tawv nqaij ua cream.
Daim duab 02: Cov Qauv Tshuaj ntawm Clotrimazole
Muaj qee qhov kev phiv ntawm clotrimazole, suav nrog xeev siab thiab khaus thaum noj qhov ncauj thiab liab thiab kub hnyiab thaum siv rau ntawm daim tawv nqaij. Cov tshuaj no thawj zaug tau muaj koob meej nyob rau xyoo 1969, thiab nws muaj nyob rau hauv cov tshuaj generic.
Lub bioavailability ntawm clotrimazole yog qhov tsis zoo lossis tsis muaj qab hau. Nws muaj peev xwm khi cov protein nyob ib ncig ntawm 90%. Cov metabolism hauv clotrimazole tshwm sim hauv daim siab. Kev tshem tawm ib nrab-lub neej ntawm cov tshuaj no yog kwv yees li 2 teev.
Qhov txawv ntawm Bifonazole thiab Clotrimazole yog dab tsi?
Bifonazole yog ib yam tshuaj uas los hauv chav kawm ntawm imidazole tshuaj tiv thaiv kab mob. Clotrimazole yog ib qho tshuaj tua kab mob uas muaj muag hauv lub npe lag luam Lotrimin. Qhov sib txawv tseem ceeb ntawm bifonazole thiab clotrimazole yog tias bifonazole tsis zoo dua piv rau clotrimazole. Tsis tas li ntawd, bifonazole feem ntau muaj raws li cov tshuaj pleev, thaum clotrimazole muaj nyob rau hauv cov tshuaj pleev ib ce thiab tshuaj qhov ncauj.
Dhau li ntawd, ob qho tshuaj muaj kev phiv. Bifonazole tuaj yeem ua rau muaj teebmeem xws li kub hnyiab thaum siv rau ntawm daim tawv nqaij, khaus, eczema, tawv nqaij qhuav, thiab lwm yam, thaum clotrimazole tuaj yeem ua rau xeev siab thiab khaus thaum noj qhov ncauj thiab liab thiab kub hnyiab thaum siv rau ntawm daim tawv nqaij.
Cov hauv qab no qhia txog qhov sib txawv ntawm bifonazole thiab clotrimazole hauv daim ntawv tabular rau ib sab ntawm kev sib piv.
Summary – Bifonazole vs Clotrimazole
Bifonazole yog ib yam tshuaj uas los hauv chav kawm ntawm imidazole tshuaj tiv thaiv kab mob. Clotrimazole yog ib qho tshuaj tua kab mob uas muaj muag hauv lub npe lag luam Lotrimin. Qhov sib txawv tseem ceeb ntawm bifonazole thiab clotrimazole yog tias bifonazole tsis zoo piv rau clotrimazole.
