Qhov sib txawv tseem ceeb ntawm DCC thiab EDC yog DCC yog ib qho kev sib txuas, hos EDC yog ib qho aliphatic compound.
DCC thiab EDC yog cov organic tebchaw. Lub sij hawm DCC sawv cev rau N, N'-Dicyclohexylcarbodiimide thaum lub sij hawm EDC sawv cev rau 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide. Ob qho no yog imides, txhais tau tias cov tebchaw no muaj -N=C=N- daim ntawv cog lus, uas sawv cev rau cov khoom ua haujlwm ntawm imides.
DCC yog dab tsi?
lo lus DCC sawv cev rau N, N′-Dicyclohexylcarbodiimide. Nws kuj tseem hu ua DCCD. Cov tshuaj formula ntawm no compound yog (C6H11N)2C. Tsis tas li ntawd, nws yog ib qho organic compound uas muaj cov qauv dav dav ntawm imide. Nws tuaj yeem ua tau raws li cov khoom siv waxy dawb uas muaj ntxhiab tsw qab. Hais txog cov khoom, cov khoom no muaj cov ntsiab lus melting tsawg heev; Yog li, nws melts yooj yim, ua rau nws tus kheej yooj yim los lis. Tsis tas li ntawd, cov khoom no yog soluble heev hauv cov kuab tshuaj xws li dichloromethane, tetrahydrofuran, acetonitrile, thiab dimethylformamide. Txawm li cas los xij, nws yog insoluble hauv dej.
Thaum xav txog cov qauv tshuaj ntawm cov tshuaj no, nws muaj cov kab C-N=C=N-C qauv ntawm qhov nruab nrab ntawm cov molecule. Yog li ntawd, cov qauv no muaj feem xyuam rau cov qauv tshuaj ntawm allene. Muaj ntau txoj hauv kev los tsim DCC. Ib txoj hauv kev suav nrog kev siv palladium acetate, iodine, thiab oxygen rau kev sib txuas ntawm cyclohexyl amine thiab cyclohexyl isocyanide. Cov tshuaj tiv thaiv no muab txog 67% DCC. Lwm txoj kev suav nrog kev siv dicyclohexylurea nyob rau hauv lub xub ntiag ntawm ib theem hloov catalyst. Txawm li cas los xij, txoj kev thib ob no tsuas yog 50% tawm los ntawm DCC.
DCC yog ib qho tseem ceeb ntawm lub cev qhuav dej rau kev tsim cov amides, ketones, thiab nitriles. Ntawm no, DCC molecule ua dej rau hauv dicyclohexylurea lossis DCU. Lub resultant compound yog insoluble nyob rau hauv ntau cov organic solvents thiab dej, yog li peb tuaj yeem yooj yim tshem tawm ntawm kev pom. Ntxiv mus, DCC yog qhov tseem ceeb hauv kev hloov cov cawv thib ob.
Dhau li ntawm, DCC yog lub npe hu ua tus inhibitor rau ATP synthase. Txawm li cas los xij, qhov tseem ceeb ntawm kev siv DCC yog kev sib txuas ntawm cov amino acids thaum lub sij hawm cov txheej txheem ntawm cov protein synthesis. Txawm hais tias tag nrho cov ntawv thov tseem ceeb ntawm DCC, nws yuav tsum tau ua tib zoo saib xyuas vim tias nws yog ib qho muaj zog ua xua thiab sensitizer. Nws feem ntau ua rau pob khaus.
EDC yog dab tsi?
Lo lus EDC sawv cev rau 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide. Cov tshuaj formula ntawm EDC yog C8H17N3. Nws kuj tseem hu ua EDAC lossis EDCI. Nws yog dej-soluble carbodiimide. Feem ntau, kev daws teeb meem ntawm EDC muaj pH ntau ntawm 4.0 txog 6.0. Feem ntau, peb tuaj yeem siv qhov sib xyaw ua ke ua tus neeg sawv cev carboxyl rau kev sib txuas ntawm thawj amines kom tau txais cov ntawv cog lus amide.
EDC yog cov khoom lag luam muaj cov organic uas tuaj yeem tsim los ntawm kev sib txuas ethyl isocyanate nrog N, N-dimethylpropane-1, 3-diamine. Cov tshuaj tiv thaiv no tsim urea uas tom qab ntawd tuaj yeem hloov mus rau hauv EDC ntawm lub cev qhuav dej. Thaum xav txog kev siv EDC, feem ntau siv rau cov carbodiimide no suav nrog peptide synthesis, protein crosslinking rau nucleic acids, thiab kev npaj ntawm immunoconjugates.
Qhov txawv ntawm DCC thiab EDC yog dab tsi?
DCC sawv cev rau N, N'-Dicyclohexylcarbodiimide thaum EDC sawv cev rau 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide. Qhov sib txawv tseem ceeb ntawm DCC thiab EDC yog DCC yog ib qho kev sib txuas, hos EDC yog ib qho aliphatic compound. Lwm qhov sib txawv loj ntawm DCC thiab EDC yog DCC yog insoluble hauv dej thaum EDC yog dej-soluble.
Ntxiv mus, thaum xav txog kev siv ob lub tebchaw, DCC yog qhov tseem ceeb raws li kev sib txuas ntawm cov amino acids thaum lub sij hawm cov txheej txheem ntawm cov protein synthesis thaum EDC muaj txiaj ntsig rau peptide synthesis, protein crosslinking rau nucleic acids, thiab hauv kev npaj. ntawm immunoconjugates.
Hauv qab infographic qhia txog qhov sib txawv ntawm DCC thiab EDC.
Summary – DCC vs EDC
DCC thiab EDC yog cov organic tebchaw, thiab DCC sawv cev rau N, N'-Dicyclohexylcarbodiimide thaum EDC sawv cev rau 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide. Qhov sib txawv tseem ceeb ntawm DCC thiab EDC yog DCC yog ib qho kev sib txuas, qhov EDC yog ib qho aliphatic compound.
