Qhov sib txawv tseem ceeb ntawm hemochromatosis thiab hemosiderosis yog hemochromatosis yog cov txheej txheem ntawm cov hlau uas ua rau cov ntaub so ntswg puas hauv lub cev, thaum hemosiderosis yog focal deposition ntawm hlau uas tsis ua rau cov ntaub so ntswg puas hauv tib neeg lub cev.
Hemochromatosis thiab hemosiderosis yog ob kab mob hlau tso nyiaj. Cov neeg laus feem ntau poob 1mg hlau ib hnub twg los ntawm cov kab mob epidermal thiab plab hnyuv. Menstruating poj niam poob ib qho ntxiv 0.5 mus rau 1 mg ib hnub los ntawm kev coj khaub ncaws. Qhov kev poob ntawm cov hlau no yog sib npaug los ntawm kev nqus hlau nyob ib ncig ntawm 10 mus rau 20 mg hauv kev noj zaub mov zoo. Kev nqus hlau yog tswj raws li cov khw muag khoom hlau hauv lub cev. Txij li thaum tsis muaj physiologic mechanism tshem tawm hlau los ntawm lub cev, cov hlau ntau absorbed yog tso rau hauv cov ntaub so ntswg.
YHemochromatosis yog dab tsi?
Hemochromatosis yog cov txheej txheem ntawm cov hlau uas ua rau cov ntaub so ntswg puas hauv tib neeg lub cev. Peb kuj hu qhov no yog hlau overload. Tus mob no feem ntau yog caj ces. Nws tuaj yeem ua rau muaj kev puas tsuaj loj rau lub plawv, daim siab, thiab txiav txiav. Cov hlau ntau dhau tuaj yeem ua rau lom. Hauv plawv, nws tuaj yeem ua rau arrhythmia thiab lub plawv tsis ua haujlwm. Cov hlau ntau dhau ntawm daim siab tuaj yeem ua rau cirrhosis, daim siab loj, mob qog noj ntshav, thiab daim siab tsis ua haujlwm. Tsis tas li ntawd, nws tseem tuaj yeem ua rau mob caj dab, mob ntshav qab zib, teeb meem ntawm tus po, pituitary caj pas, qog adrenal, gall zais zis, thyroid, thiab kev ua me nyuam. Ib qho hlau overload tuaj yeem ua rau daim tawv nqaij zoo dua grey lossis bronze. Hemochromatosis feem ntau tshwm sim, thiab nws cuam tshuam ntau tshaj li ib lab tus neeg Asmeskas.
Daim duab 01: Micrograph ntawm Hemochromatosis Liver
Muaj ob hom hemochromatosis: lawv yog keeb kwm (primary) thiab theem nrab. Hereditary hemochromatosis yog vim muaj kev hloov pauv ntawm ntau cov noob xws li HFE, HJV, HAMP, thiab SLC40A1. Ntawm qhov tod tes, theem nrab hemochromatosis yog vim muaj kev kho mob lossis lwm yam mob xws li ntshav ntshav, hloov ntshav, tshuaj hlau, raum lim ntshav, kab mob siab C, thiab kab mob siab rog. Cov tsos mob ntawm hemochromatosis tej zaum yuav muaj xws li qaug zog, lub plawv dhia, lub nrig hlau, mob pob qij txha, mob plab, thiab qhov hnyav tsis tau piav qhia. Tus mob no feem ntau yog kuaj los ntawm kev kuaj ntshav, kuaj caj ces, kuaj lub siab, thiab MRI. Tsis tas li ntawd, cov kev kho mob yuav suav nrog kev hloov pauv kev noj haus, kev kho mob hlau chelation, thiab kho phlebotomy.
Hemosiderosis yog dab tsi?
Hemosiderosis yog focal deposition ntawm hlau uas tsis ua rau cov ntaub so ntswg puas nyob rau hauv tib neeg lub cev. Nws yog ib hom hlau overload teeb meem uas ua rau tsub zuj zuj ntawm hemosiderin. Hauv qhov xwm txheej no, cov hlau tau tso tawm los ntawm cov qe ntshav liab extravasated tso rau hauv lub cev thiab cov nyiaj hemosiderin tseem ceeb tuaj yeem tsim nyob rau hauv lub cev. Cov kab mob inflammatory mob ntev xws li cov kab mob uas tsis yog-alcoholic fatty siab kab mob thiab metabolic syndrome tuaj yeem ua rau hemosiderosis.
Daim duab 02: Hemosiderosis
Hemosiderosis tuaj yeem muab faib ua peb hom: hloov ntshav hemosiderosis, idiopathic pulmonary hemosiderosis, thiab ntshav qab zib hemosiderosis. Cov tsos mob ntawm tus mob no yuav muaj xws li hnoos, ua pa nyuaj, qaug zog, ua tsis taus pa, mob hauv lub cev, hawb pob, thiab kev loj hlob qeeb hauv cov menyuam yaus. Muaj ntau qhov kev ntsuam xyuas los kuaj xyuas tus mob no: ntshav ferritin, daim siab biopsy thiab MRI. Tsis tas li ntawd, cov kev kho mob tuaj yeem suav nrog kev kho mob hlau chelation, tso tseg cov ntshav hloov, corticosteroids los ntshav hauv lub ntsws, kho cov pa oxygen rau lub ntsws, cov tshuaj tiv thaiv kab mob rau pulmonary hypertension thiab lub ntsws hloov pauv.
Dab tsi zoo sib xws ntawm Hemochromatosis thiab Hemosiderosis?
- Hemochromatosis thiab hemosiderosis yog ob yam kab mob hlau tso.
- Ob leeg yog hlau overload.
- Lub siab thiab lub siab raug cuam tshuam los ntawm ob qho xwm txheej.
- Lawv yog cov mob kho tau.
- Ob qho xwm txheej tuaj yeem tshwm sim vim kev hloov ntshav.
Qhov txawv ntawm Hemochromatosis thiab Hemosiderosis yog dab tsi?
Hemochromatosis yog cov txheej txheem ntawm cov hlau uas ua rau cov ntaub so ntswg puas hauv tib neeg lub cev, thaum hemosiderosis yog focal deposition ntawm hlau uas tsis ua rau cov ntaub so ntswg puas nyob rau hauv tib neeg lub cev. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm hemochromatosis thiab hemosiderosis. Tsis tas li ntawd, kev sib sau ntawm hemosiderin tsis pom hauv hemochromatosis. Tab sis, tsub zuj zuj ntawm hemosiderin yog pom nyob rau hauv hemosiderosis.
Cov ntawv sau hauv qab no qhia qhov sib txawv ntawm hemochromatosis thiab hemosiderosis hauv daim ntawv teev npe rau ib sab ntawm kev sib piv.
Summary – Hemochromatosis vs Hemosiderosis
Hlau yog cov ntxhia hauv tib neeg lub cev xav tau kev loj hlob thiab kev loj hlob. Hemochromatosis thiab hemosiderosis yog ob hom kab mob hlau. Hemochromatosis yog ib qho systemic deposition ntawm hlau uas ua rau cov ntaub so ntswg puas nyob rau hauv tib neeg lub cev, thaum hemosiderosis yog focal deposition ntawm hlau uas tsis ua rau tej ntaub so ntswg puas nyob rau hauv tib neeg lub cev. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm hemochromatosis thiab hemosiderosis.
