Qhov Tseem Ceeb - PT vs PTT
ntshav coagulation yog txheej txheem uas tiv thaiv los ntshav ntau dhau tom qab raug mob. Thaum cov hlab ntsha raug mob, platelets hauv cov ntshav tsim ib ntus ntsaws ntawm qhov chaw raug mob kom tsis txhob los ntshav. Txawm li cas los xij, nws tsis muaj zog txaus kom tsis txhob los ntshav. Yog li ntawd, cov ntshav coagulation cascade activates thiab ua ib tug fibrin mesh los txhawb lub platelet plug. Platelets, ua ke nrog cov ntshav plasma thiab fibrins, ua kom muaj cov ntshav khov khov ntawm qhov chaw raug mob los kaw qhov txhab. Yog li ntawd, cov ntshav ntau dhau los ntawm qhov txhab raug tso tseg. Muaj ntau yam coagulation sib txawv koom nrog hauv cov ntshav txhaws. Ntawm lawv, prothrombin thiab prothrombin activator (thromboplastin) yog qhov tseem ceeb heev rau kev tsim cov thrombin, uas yog lub ntsiab enzyme uas catalyzes fibrin tsim. Cov txheej txheem ntshav coagulation tuaj yeem pom qhov txawv txav uas tuaj yeem ua rau los ntshav. Yog li ntawd, muaj ntau yam kev kuaj ntshav tsim los kom paub txog cov teeb meem hauv thiab ntshav txhaws thiab los ntshav. Prothrombin Time (PT) thiab Partial Thromboplastin Time (PTT) yog ob qho kev kuaj ntshav uas ntsuas lub sij hawm coj los tsim cov ntshav txhaws. Qhov sib txawv tseem ceeb ntawm PT thiab PTT kev xeem yog qhov kev xeem PT ntsuas qhov kev ncaj ncees ntawm cov txheej txheem extrinsic thiab cov yam tseem ceeb rau ob lub tshuab thaum PTT ntsuas qhov kev ncaj ncees ntawm lub cev thiab cov yam ntxwv ntawm ob lub cev.
PT yog dab tsi?
Cov ntshav tsis txaus tiv thaiv kev tsim cov coagulation yam lossis ua kom cov ntshav coagulation tsis raug. Cov malformations no yog tshwm sim los ntawm ib co tshuaj, kab mob siab, vitamin K deficiency, thiab lwm yam. Thaum muaj los ntshav, nws yuav ua rau muaj kev pheej hmoo ntawm los ntshav ntau dhau thiab tsub zuj zuj ntawm cov ntshav nyob rau hauv daim tawv nqaij (hematoma). Tag nrho cov teeb meem no yog vim qhov txawv txav ntawm cov ntshav txhaws. PT yog ib hom kev kuaj ntshav uas ntsuas lub sijhawm ua rau cov ntshav txhaws lossis ntshav coagulation. Kev kuaj PT feem ntau yog ua los tshawb xyuas cov teeb meem los ntshav, lossis nws tau ua ua ntej kev phais kom kuaj xyuas qhov muaj feem yuav los ntshav ntau dhau.
PT xeem feem ntau tsom rau kev ntsuas kev ncaj ncees ntawm cov ntshav coagulation extrinsic thiab cov coagulation yam tshwm sim rau ob txoj hauv kev. Prothrombin yog ib qho tseem ceeb plasma protein ua los ntawm lub siab. Vitamin K yuav tsum muaj los ua prothrombin. Prothrombin hloov mus rau hauv thrombin los ntawm prothrombin activator. Kev tsim cov thrombin yog qhov tseem ceeb ntawm kev koom tes hauv cov txheej txheem txhaws. Kev ntsuas lub sij hawm prothrombin yog qhov tseem ceeb vim nws qhia seb tsib yam ntshav txhaws (factor I, II, V, VII, thiab X) puas tshwm sim los tsis tau.
PT ntsuas hauv vib nas this. Txawm li cas los xij, nws tau tshaj tawm raws li tus naj npawb ntawm thoob ntiaj teb normalized piv (INR). Lub sijhawm prothrombin ib txwm nyob ntawm 11 txog 13.5 vib nas this. Hauv INR tus lej, qhov ntau yog 0.9 txog 1.1. Lub sij hawm prothrombin tuaj yeem txuas ntxiv tau vim muaj ntau yam xws li cov tshuaj ua kom ntshav ntshav, qib qis ntawm cov ntshav txhaws, tsis muaj cov ntshav txhaws, thiab kev hloov pauv hauv cov haujlwm ntawm cov ntshav txhaws.
Daim duab 01: PT test
PT kuaj yog ua los ntawm kev kuaj ntshav los ntawm tus neeg mob thiab ntxiv qee yam tshuaj (calcium thiab thromboplastin) rau nws. Tom qab ntawd lub sijhawm siv rau kev tsim cov fibrin clot yog ntsuas. Yog tias nws nyob hauv lub sijhawm ib txwm muaj, nws tuaj yeem txiav txim siab tias tus neeg mob tsis muaj ntshav los ntshav.
PTT yog dab tsi?
Ib nrab thromboplastin lub sijhawm kuaj yog lwm qhov kev ntsuas uas ntsuas lub sijhawm coj mus rau ntshav coagulation. Nws ntsuas qhov ncaj ncees ntawm cov ntshav txhaws hauv lub cev thiab coagulation yam ntawm txoj hauv kev. Qhov kev sim no tau ua ua ke nrog kev kuaj PT txhawm rau tshawb xyuas cov ntshav los ntshav ntau dhau los yog ntshav txhaws. Thaum muaj kev raug mob, ob qho tib si sab hauv thiab sab nraud txoj hauv kev pib thiab ua kom nquag plias ntawm coagulation yam tshwm sim los tsim cov ntshav txhaws. PTT test yog siv los ntsuas cov coagulation yam XII, XI, IX, VIII, X, V, II (prothrombin), thiab kuv (fibrinogen).
Daim duab 02: Coagulation Diagram
PTT kuaj nrog rau kev kuaj PT rau ntau qhov laj thawj xws li los ntshav tsis tau piav qhia, bruising yooj yim, tsim cov ntshav txhaws hauv cov hlab ntsha lossis cov hlab ntsha, mob siab, thiab lwm yam. Cov txiaj ntsig ntawm PTT thiab PT kuaj yuav nthuav qhia cov ntsiab lus tiag tiag txog cov laj thawj ntawm cov ntshav txhaws. Yog li ntawd, cov kws kho mob feem ntau sau ob qho kev xeem ua ke.
Qhov Zoo sib xws ntawm PT thiab PTT yog dab tsi?
PT thiab PTT kuaj ntshav tau ua tiav los ntsuas lub sijhawm nws siv koj cov ntshav txhaws
Qhov txawv ntawm PT thiab PTT yog dab tsi?
PT vs PTT |
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| PT kuaj ntsuas kev ncaj ncees ntawm txoj hauv kev extrinsic thiab txoj hauv kev sib koom ua ke. | PTT kev ntsuas ntsuas kev ncaj ncees ntawm txoj hauv kev hauv nruab nrog cev thiab feem ntau coagulation yam. |
| Cov laj thawj sib txawv | |
| PT kuaj ntsuas cov coagulation yam VII, X, V, II, thiab kuv (fibrinogen). | PTT kuaj ntsuas cov coagulation yam XII, XI, IX, VIII, X, V, II (prothrombin), thiab I (fibrinogen). |
| Tshuaj Ntshav Qab Zib | |
| PT kuaj xyuas warfarin. | PTT kuaj xyuas heparin. |
Summary – PT vs PTT
PT thiab PTT yog ob qhov kev kuaj ntshav los tshawb xyuas cov teeb meem los ntshav. PT yog ib qho kev ntsuas ntawm kev ncaj ncees ntawm extrinsic thiab kawg txoj hauv kev ntawm coagulation cascade. PTT yog ib qho kev ntsuas ntawm kev ncaj ncees ntawm lub hauv paus thiab qhov kawg txoj hauv kev ntawm cov ntshav coagulation. PTT kuaj ntsuas cov coagulation yam XII, XI, IX, VIII, X, V, II (prothrombin), thiab I (fibrinogen) thiab PT kuaj ntsuas cov coagulation yam VII, X, V, II, thiab I (fibrinogen). Yog li, qhov sib txawv ntawm PT thiab PTT nyob ntawm lawv cov haujlwm tiag tiag. Cov txiaj ntsig ntawm ob qhov kev ntsuam xyuas ua ke xaus qhov laj thawj vim li cas los ntshav ntau dhau los yog ntshav txhaws.
Download PDF Version of PT vs PTT
Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline hom phiaj raws li cov ntawv sau tseg. Thov download PDF version ntawm no Qhov txawv Ntawm PT thiab PTT.
