Qhov sib txawv tseem ceeb ntawm kev thim rov qab thiab kev hloov pauv kev hloov pauv yog qhov hloov pauv hloov pauv yog qhov hloov pauv uas ua kom rov zoo li qub hom DNA sib lawv liag rov qab thaum qhov kev hloov pauv hloov pauv yog qhov hloov pauv thib ob ntawm qhov chaw sib txawv uas cuam tshuam cov txiaj ntsig phenotypic ntawm thawj kev hloov pauv..
Kev hloov pauv yog qhov hloov pauv hauv nucleotide ib ntu ntawm DNA. Txij li cov nucleotide ib ntus ntawm cov noob muaj cov ntaub ntawv tseem ceeb los tsim cov protein, ib qho kev hloov nucleotide tuaj yeem ua rau muaj kev cuam tshuam. Cov kev hloov pauv feem ntau yog deleterious, thaum qee qhov kev hloov pauv yuav muaj txiaj ntsig zoo hauv qee qhov chaw. Kev hloov pauv tshwm sim raws li qhov yuam kev ntawm DNA luam tawm thaum lub sijhawm faib ntawm tes lossis feem ntau yog vim muaj tshuaj lom neeg, hluav taws xob, lossis ib puag ncig. Qee qhov kev hloov pauv tau txais mus rau tiam tom ntej thaum qee qhov tsis kis. Muaj ntau hom kev hloov pauv. Reversion mutation restores cov tsiaj qus hom DNA sib lawv liag thaum suppression mutation suppresses lub phenotype ntawm lwm mutation uas yog hu ua thawj kev hloov.
Kev hloov pauv hloov pauv yog dab tsi?
Kev hloov pauv hloov pauv yog ib hom kev hloov pauv uas ua kom rov zoo dua cov nucleotide ib ntus ntawm hom tsiaj qus. Hauv lwm lo lus, kev hloov pauv hloov pauv hloov pauv qhov qub yam tsiaj qus nucleotide sib lawv liag. Yog li ntawd, kev hloov pauv hloov pauv tuaj yeem rov ua haujlwm ntawm cov noob hloov pauv rov qab.
Daim duab 01: Kev hloov pauv
Kev hloov pauv hloov feem ntau tshwm sim vim qhov poob ntawm kev tswj hwm. Tsis tas li ntawd, kev hloov pauv tuaj yeem yog los ntawm kev hloov pauv hloov pauv. Yog tias cov noob caj noob ces thiab cov tshuaj tua kab mob sib txuas zoo sib xws, peb tuaj yeem xav tias qhov thim rov qab yog los ntawm kev hloov pauv hloov. Kev hloov pauv hauv paus thiab kev hloov pauv hloov pauv tuaj yeem ua rau rov qab hloov pauv. Nyob rau hauv lub hauv paus hloov, lub mutant puag yuav tsum tau hloov los ntawm lub hauv paus khub nyob rau hauv qus hom. Hauv kev hloov pauv hloov pauv, nws yuav tsum tau muab tshem tawm ntawm ib lub hauv paus tshwj xeeb los ntawm ib qho chaw tshwj xeeb, lossis ntxig ib lub hauv paus rau hauv ib qho chaw tshwj xeeb.
Kev Tawm Tsam Tawm Tsam yog dab tsi?
Kev Tiv Thaiv kev hloov pauv yog qhov hloov pauv thib ob uas ua rau cov nyhuv phenotypic ntawm thawj qhov kev hloov pauv. Kev txwv kev hloov pauv tshwm sim ntawm qhov chaw sib txawv ntawm thawj qhov kev hloov pauv. Nws tuaj yeem kho qhov qub hauv paus ib ntus ntawm cov noob. Muaj ob hom kev txwv kev hloov pauv. Lawv yog intragenic suppression mutation thiab intergenic (extragenic) suppression mutations.
Daim duab 02: Kev Tiv Thaiv Kev Hloov Pauv
Nyob rau hauv intragenic suppression, suppressor lies nyob rau hauv tib lub noob raws li qhov qub hloov. Nyob rau hauv intergenic suppression, suppressor nyob rau lwm qhov hauv genome (feem ntau yog cov noob sib txawv) piv rau qhov chaw ntawm thawj qhov kev hloov pauv.
Dab tsi yog qhov zoo sib xws ntawm Kev thim rov qab thiab kev tawm tsam kev hloov pauv?
- Kev hloov pauv thiab kev txwv kev hloov pauv yog ob hom kev hloov pauv.
- Qee qhov kev hloov pauv hloov pauv yog kev hloov pauv hloov pauv.
- Ob qhov kev hloov pauv hloov kho qhov phenotype ntawm cov noob qub.
Dab tsi yog qhov txawv ntawm Kev Hloov Kho thiab Kev Tiv Thaiv Kev Hloov Pauv?
Kev hloov pauv hloov pauv yog qhov hloov pauv uas rov ua haujlwm ntawm cov noob caj noob ces thaum kev hloov pauv hloov pauv yog qhov hloov pauv uas txwv cov phenotype ntawm lwm qhov kev hloov pauv. Yog li, qhov no yog qhov sib txawv ntawm kev thim rov qab thiab kev txwv kev hloov pauv. Reversion mutation thim rov qab cov thawj hauv paus ib theem zuj zus ntawm DNA thaum suppression mutation suppresses cov phenotypic nyhuv ntawm thawj kev hloov los yog restores tus thawj kev ua ntawm cov noob.
Hauv qab no yog cov ntsiab lus ntawm qhov sib txawv ntawm kev thim rov qab thiab kev tawm tsam kev hloov pauv hauv daim ntawv teev npe.
Summary – Reversion vs Suppression Mutation
Kev hloov pauv hloov pauv rov qab cov txiaj ntsig ntawm thawj qhov kev hloov pauv. Nws restores lub hauv paus ib theem zuj zus ntawm cov noob. Yog li ntawd, cov kev ua ntawm cov tsiaj qus hom gene resumes. Kev tawm tsam kev hloov pauv yog kev hloov pauv uas cuam tshuam cov nyhuv phenotypic ntawm thawj cov noob. Nws kuj rov kho cov kev ua gene hauv qhov kev hloov pauv thawj zaug. Kev tawm tsam tuaj yeem yog intragenic lossis intergenic. Kev hloov pauv hloov pauv tuaj yeem tshwm sim vim kev hloov pauv hloov pauv yog tias cov noob caj noob ces thiab cov tshuaj tua kab mob sib raug zoo. Yog li, qhov no yog cov ntsiab lus ntawm qhov sib txawv ntawm kev thim rov qab thiab kev tawm tsam kev hloov pauv.
