Qhov Tseem Ceeb Qhov txawv - Chondroblasts vs Chondrocytes
Pob txha mos yog cov ntaub so ntswg tshwj xeeb uas pom muaj nyob hauv ntau qhov chaw ntawm lub cev. Chondrogenesis yog cov txheej txheem uas tsim cov pob txha mos los ntawm cov ntaub so ntswg mesenchyme. Muaj ob hom cell loj hauv pob txha hu ua chondroblasts thiab chondrocytes. Chondroblasts nquag faib cov hlwb tsis paub qab hau uas tsim cov matrix extracellular thiab cov chondrocytes. Chondrocytes yog cov hlwb sib txawv uas koom nrog hauv kev nthuav dav ntawm cov as-ham, kev saib xyuas, thiab kho cov kab mob extracellular matrix ntawm pob txha mos. Qhov sib txawv tseem ceeb ntawm chondrocytes thiab chondroblasts yog tias chondroblasts yog cov pob txha mos uas tsis paub tab pom nyob ze ntawm lub perichondrium thaum chondrocytes yog cov pob txha mos uas paub tab pom pom nyob rau hauv cov kab mob extracellular matrix.
Chondroblasts yog dab tsi?
Chondroblasts, tseem hu ua chondroplasts, yog cov hlwb tsis paub qab hau, uas yog qhov tseem ceeb rau kev txhim kho pob txha mos. Lawv nyob rau ntawm ntug ntawm pob txha mos nyob rau hauv lub perichondrium qhov chaw ntawm cell faib tshwm sim raws li ob qhov chaw tawm tsam. Chondroblasts tseem hu ua perichondrial hlwb los yog mesenchymal progenitor hlwb, uas ua rau chondrocytes thiab cov khoom ntawm extracellular matrix. Chondroblasts mas secrete hom ob collagen thiab lwm yam extracellular matrix Cheebtsam.
Daim duab 01: Chondroblasts hauv cov pob txha mos
Chondrocytes yog dab tsi?
Chondrocytes yog cov hlwb tshwj xeeb pom nyob rau hauv cov pob txha mos matrix kab noj hniav hu ua lacunae. Lawv yog matured thiab sib txawv hlwb ntawm chondroblasts. Lub luag haujlwm tseem ceeb ntawm chondrocyte yog kev sib txuas, tswj thiab kho cov txheej txheem ntxiv ntawm cov pob txha mos. Extracellular matrix yog tsim los ntawm sib npaug sib npaug ntawm collagen fibrils thiab proteoglycans. Ob yam no yog tsim los ntawm chondrocytes hauv pob txha mos. Txawm li cas los xij, chondrocytes yog cov hlwb uas tsis muaj zog nrog lub peev xwm rov tsim dua tshiab.
Daim duab 02: Chondrocytes hauv pob txha mos
Pob txha mos tsis muaj cov hlab ntsha lossis cov hlab ntsha. Yog li ntawd, txhawm rau tswj cov qauv thiab kev ua haujlwm ntawm pob txha mos, chondrocytes yuav tsum tau txais cov as-ham los ntawm matrix. Cov khoom noj tau muab rau chondrocytes los ntawm txoj kev hu ua diffusion. Chondrocytes malfunction tuaj yeem ua rau muaj kab mob hu ua osteoarthritis. Nws yog kab mob pob txha degenerative tshwm sim los ntawm kev tawg ntawm cov ntaub so ntswg homeostasis.
Kev hloov pauv ntawm pob txha mos yog txiav txim siab los ntawm tus lej ntawm chondrocytes tam sim no hauv pob txha mos. Muaj peb hom pob txha mos hu ua hyaline, elastic thiab fibrocartilage raws li qhia hauv daim duab 03.
Daim duab 3: Cov pob txha mos
Qhov txawv ntawm Chondroblasts thiab Chondrocytes yog dab tsi?
Chondroblasts vs Chondrocytes |
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| Chondroblasts yog ib hom hlwb pom nyob rau hauv pob txha mos uas yog lub luag haujlwm rau kev txhim kho pob txha mos. | Chondrocytes yog ib hom ntawm cov hlwb tshwj xeeb pom hauv pob txha mos uas yog lub luag haujlwm rau kev saib xyuas pob txha mos. |
| Cov no nyob rau hauv ob qhov kev tawm tsam loj hlob ntawm cov pob txha mos hauv qab perichondrium | Cov no pom muaj nyob rau hauv lub lacunae. |
| Cov no yog cov hlwb tsis paub tab uas nquag faib. | Cov no yog cov hlwb tsis paub tab uas tsis muaj zog thiab sib txawv. |
| Chondroblasts tsim chondrocytes thiab extracellular matrix ntawm pob txha mos. | Chondrocytes tsim cov khoom ntawm extracellular matrix thiab tswj cov pob txha mos thiab ua haujlwm. |
| Chondrocyte Formation | |
| Cov no yog cov hlwb progenitor ntawm chondrocytes | Chondrocytes yog tsim los ntawm chondroblasts |
Summary - Chondroblasts thiab Chondrocytes
Chondroblasts thiab chondrocytes yog ob hom hlwb pom hauv pob txha mos. Chondroblasts nquag faib cov hlwb tsis paub tab nyob ze ntawm lub perichondrium ntawm pob txha mos. Lawv yog cov hlwb tiag tiag uas tsim cov pob txha mos. Chondroblasts yog progenitors ntawm chondrocytes thiab extracellular matrix ntawm pob txha mos. Thaum chondroblasts tau kos rau hauv pob txha mos matrix thiab tsis sib faib, lawv dhau los ua chondrocytes. Chondrocytes yog cov hlwb tshwj xeeb uas paub tab pom hauv pob txha mos uas tsim thiab tswj cov pob txha mos matrix. Chondrocytes yog tsim los ntawm collagen fibrils thiab proteoglycans thiab lub luag hauj lwm rau qhov yooj ntawm pob txha mos. Qhov no yog qhov txawv ntawm chondroblasts thiab chondrocytes.
