Qhov sib txawv tseem ceeb ntawm acidosis thiab acidemia yog acidosis yog qhov nce acidity hauv cov ntshav thiab lwm yam ntaub so ntswg hauv lub cev, thaum kev kawm yog lub xeev ntawm pH ntshav qis.
Ntshav yog ib txwm yooj yim. pH ntawm cov ntshav yog li 7.35 txog 7.45. Cov txheej txheem ntawm ntsuas acidity thiab alkalinity hauv lub cev yog hu ua acid-base balance. Lub ntsws, ob lub raum, thiab cov kab mob tsis nyob hauv lub cev pab txhawb hom kev ntsuas acidity thiab alkalinity. Qhov txawv txav ntawm cov kua qaub-puag tshuav yuav ua rau muaj teeb meem xws li acidosis (cov kua qaub ntau dhau hauv cov ntshav), acidemia (pH ntshav qis), alkalosis (cov ntshav ntau dhau), thiab alkalemia (pH ntshav siab). Acidosis thiab acidemia yog ob qho kev kho mob vim yog qhov tsis zoo ntawm acid-base balancing.
Acidosis yog dab tsi?
Acidosis yog cov txheej txheem uas ua rau muaj acidity hauv cov ntshav thiab lwm cov ntaub so ntswg hauv lub cev. Muaj ob hom acidosis: metabolic acidosis thiab ua pa acidosis. Ua pa acidosis tshwm sim thaum CO2 ua rau hauv lub cev. Feem ntau, lub ntsws tshem CO2 thaum ua pa. Txawm li cas los xij, qee zaum, lub cev tsis tuaj yeem tshem tawm CO 2, ua rau ua rau ua pa acidosis. Cov mob no tuaj yeem yog mob hawb pob, raug mob rau hauv siab, rog rog, sedative misuse, haus cawv ntau dhau, cov leeg tsis muaj zog hauv siab, thiab teeb meem ntawm lub paj hlwb. Metabolic acidosis, ntawm qhov tod tes, tshwm sim thaum lub raum tsis tshem tawm cov kua qaub txaus. Muaj ntau hom metabolic acidosis xws li ntshav qab zib acidosis, hyperchloremic acidosis, lactic acidosis, thiab raum tubular acidosis.
Daim duab 01: Acidosis
Cov kev pheej hmoo rau acidosis suav nrog kev noj zaub mov muaj roj ntau, lub raum tsis ua haujlwm, rog rog, lub cev qhuav dej, tshuaj aspirin lossis methanol lom, thiab ntshav qab zib. Cov tsos mob ntawm acidosis tej zaum yuav muaj xws li qaug zog, tsis meej pem, ua tsis taus pa luv, tsaug zog, mob taub hau, jaundice, nce plawv dhia, ua tsis taus pa tsw fruity, tsis qab los noj mov, thiab lwm yam. Tus mob no yuav kuaj tau los ntawm kev kuaj ntshav, X-rays, thiab pulmonary. kev kuaj ua haujlwm. Cov kev xaiv kho mob muaj xws li muab cov tshuaj bicarbonate, txuas ntxiv ua pa zoo uas pab ua pa, thiab kho cov mob hauv qab xws li ntshav qab zib, mob raum tsis ua haujlwm, thiab lwm yam.
Acidemia yog dab tsi?
Kev kawm yog lub xeev ntawm pH ntshav qis. Acidemia tshwm sim thaum pH ntawm arterial poob qis dua 7.35. Nws qhov sib piv, alkalemia, tshwm sim thaum pH nce ntau dua 7.45. Hauv cov tsiaj nyeg, cov pH ntawm cov ntshav arterial nyob nruab nrab ntawm 7.35 thiab 7.50, nyob ntawm seb hom tsiaj twg. Cov kev hloov pauv hauv cov ntshav hlab ntsha pH sab nraum qhov tshwj xeeb no ua rau muaj kev puas tsuaj ntawm tes tsis muaj zog. Organic acidemia yog ib hom kab mob acidemia. Qhov mob no yog vim cov amino acid metabolism tsis xws luag uas ua rau muaj kev tsim cov amino acids thiab qee yam khib chained fatty acids hauv lub cev. Muaj plaub yam tseem ceeb ntawm cov organic acidemia: methylmalonic acidemia, propionic acidemia, isovaleric acidemia, thiab maple syrup urine disease.
Daim duab 02: Acidemia
Qhov ua rau tus mob no yog qhov tsis zoo autosomal noob rau ntau yam enzymes uas tseem ceeb rau cov amino acid metabolism. Cov tsos mob ntawm cov organic acidemia muaj xws li apnea lossis ua pa nyuaj, ntuav rov qab, lub cev qhuav dej, hypotonia, qaug dab peg, tsis qab los noj mov, kev loj hlob qeeb, thiab lethargy. Tsis tas li ntawd, cov organic acidemia tuaj yeem kuaj tau los ntawm kev tsom xam cov zis los ntawm cov pa roj chromatography thiab loj spectrometry, kev tshuaj ntsuam cov menyuam mos los ntawm tandem mass spectrometry, thiab kuaj ntshav pH. Kev kho mob rau cov organic acidemia suav nrog kev noj cov protein tsawg, cov kua dej hauv cov hlab ntsha, hloov cov amino acid, cov vitamins ntxiv, carnitine, induced anabolism, thiab tube noj.
Tsis tas li ntawd, muaj qee yam acidemia tshwj xeeb cuam tshuam rau fetuses, xws li fetal metabolic acidemia thiab fetal respiratory acidemia. Fetal metabolic acidemia txhais tau tias yog lub plab pH tsawg dua 7.20. Ntawm qhov tod tes, fetal repertory acidemia txhais tau tias yog umbilical artery PCO2 ntawm 66 los yog siab dua lossis umbilical leeg PCO2ntawm 50 lossis siab dua.
Dab tsi zoo sib xws ntawm Acidosis thiab Acidemia?
- Acidosis thiab acidemia yog ob yam mob vim yog qhov tsis zoo ntawm acid-base balancing.
- Cov kev mob nkeeg no muaj cov tsos mob zoo sib xws.
- Ob qho kev kho mob tuaj yeem tshwm sim vim qhov ua rau metabolic thiab ua pa ua pa.
- Lawv tuaj yeem kuaj pom tau los ntawm kev kuaj ntshav thiab zis.
- Yog tias tswj tsis tau zoo, ob qho kev kho mob yuav ua rau mob hnyav.
Qhov txawv ntawm Acidosis thiab Acidemia yog dab tsi?
Acidosis yog cov txheej txheem uas ua rau muaj acidity hauv cov ntshav thiab lwm cov ntaub so ntswg hauv lub cev, thaum kev kawm yog lub xeev ntawm cov ntshav pH qis. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm acidosis thiab acidemia. Ntxiv mus, ntau hom acidosis muaj xws li ua pa acidosis thiab metabolic acidosis, thaum ntau hom acidemia muaj xws li organic acidemia, fetal metabolic acidemia, thiab fetal respiratory acidemia.
Cov hauv qab no qhia txog qhov sib txawv ntawm acidosis thiab acidemia hauv daim ntawv tabular rau ib sab ntawm kev sib piv.
Summary – Acidosis vs Acidemia
Acidosis thiab acidemia yog ob yam mob vim yog qhov tsis tsim nyog acid-base ntsuas hauv tib neeg lub cev. Acidosis hais txog qhov nce acidity hauv cov ntshav thiab lwm cov ntaub so ntswg hauv lub cev, thaum kev kawm yog lub xeev ntawm cov ntshav pH tsawg. Yog li, qhov no qhia txog qhov sib txawv ntawm acidosis thiab acidemia
