Qhov sib txawv tseem ceeb ntawm phenytoin thiab phenytoin sodium yog tias phenytoin yog dej-soluble tsawg, whereas phenytoin sodium yog dej-soluble heev.
Phenytoin muaj txiaj ntsig zoo li tshuaj tiv thaiv qaug dab peg. Phenytoin sodium yog sodium ntsev ntawm phenytoin. Ob lub tebchaw no muaj cov tshuaj lom neeg thiab lub cev zoo sib xws. Txawm li cas los xij, lawv muaj qhov sib txawv hauv dej.
YPhenytoin yog dab tsi?
Phenytoin yog tshuaj uas muaj txiaj ntsig zoo li tshuaj tiv thaiv qaug dab peg. Nws yog abbreviated li PHT. Lub npe ntawm cov tshuaj no yog Dilantin. Cov tshuaj no muaj txiaj ntsig zoo rau kev tiv thaiv ntawm tonic-clonic qaug dab peg nrog rau kev qaug dab peg. Txawm li cas los xij, nws tsis tuaj yeem tiv thaiv kev qaug dab peg. Chav kawm tshuaj uas cov tshuaj no belongs rau lub npe hu ua cov tshuaj anticonvulsant.
Txoj kev ntawm kev tswj hwm rau cov tshuaj phenytoin suav nrog kev tswj hwm qhov ncauj thiab kev txhaj tshuaj hauv cov hlab ntsha. Lub bioavailability ntawm cov tshuaj no hauv peb lub cev yog li 70-100% thaum noj qhov ncauj. Lub peev xwm ntawm cov protein khi ntawm cov tshuaj no yog kwv yees li 95%. Cov metabolism hauv cov tshuaj no tshwm sim hauv daim siab. Kev tshem tawm ib nrab-lub neej ntawm phenytoin yog 10-22 teev. Ntxiv mus, lub sij hawm ntawm qhov kev txiav txim ntawm cov tshuaj no yog hais txog 24 teev. Excretion tshwm sim los ntawm txoj hlab zis los yog kua tsib.
Muaj qee qhov mob me me ntawm phenytoin; xeev siab, mob plab, tsis qab los noj mov, ua haujlwm tsis zoo, ua kom cov plaub hau loj hlob tuaj, thiab ua kom cov pos hniav loj tuaj. Txawm li cas los xij, tuaj yeem muaj qee qhov kev mob tshwm sim hnyav, uas suav nrog kev pw tsaug zog, ua rau nws tus kheej raug mob, mob siab, mob pob txha pob txha, ntshav siab, thiab lwm yam.
Phenytoin Sodium yog dab tsi?
Phenytoin sodium yog sodium ntsev ntawm phenytoin compound. Nws yog ib qho derivative ntawm phenytoin thiab, feem ntau nws yog cov tshuaj nquag hauv cov tshuaj phenytoin. Yog li, cov tshuaj no kuj tseem ceeb raws li cov tshuaj tiv thaiv qaug dab peg uas muaj txiaj ntsig zoo hauv kev tiv thaiv tonic-clonic qaug dab peg thiab focal qaug dab peg. Txoj hauv kev ntawm kev tswj hwm rau phenytoin sodium yog kev tswj hwm qhov ncauj.
Vim tias phenytoin sodium yog sodium derivative ntawm phenytoin compound, cov tshuaj thiab lub cev ntawm ob lub tebchaw feem ntau zoo ib yam. Txawm li cas los xij, phenytoin sodium yog soluble hauv dej vim nws muaj sodium cation. Nws yog insoluble hauv ether thiab chloroform. Hauv kev sib piv, phenytoin (tsis muaj sodium) yog cov dej-soluble tsawg dua.
Dab tsi yog qhov zoo sib xws ntawm Phenytoin thiab Phenytoin Sodium?
- Phenytoin thiab Phenytoin Sodium yog cov tshuaj tseem ceeb raws li cov tshuaj tiv thaiv qaug dab peg uas muaj txiaj ntsig zoo hauv kev tiv thaiv tonic-clonic qaug dab peg thiab focal qaug dab peg
- Lawv yog cov organic tebchaw.
- Ob leeg yog soluble hauv dej tab sis insoluble hauv ether thiab chloroform.
Qhov txawv ntawm Phenytoin thiab Phenytoin Sodium yog dab tsi?
Ob qho tib si phenytoin thiab phenytoin sodium nyiam sib koom cov tshuaj lom neeg thiab lub cev zoo sib xws. Txawm li cas los xij, lawv muaj qhov sib txawv hauv dej. Qhov sib txawv tseem ceeb ntawm phenytoin thiab phenytoin sodium yog tias phenytoin tsis tshua muaj dej-soluble, whereas phenytoin sodium yog dej-soluble heev. Phenytoin yog cov tshuaj tsis-ionized, thaum phenytoin sodium yog ib qho tshuaj ionized nrog sodium cation.
Hauv qab no yog cov ntsiab lus ntawm qhov sib txawv ntawm phenytoin thiab phenytoin sodium nyob rau hauv daim ntawv tabular rau ib sab ntawm kev sib piv.
Summary – Phenytoin vs Phenytoin Sodium
Phenytoin yog tshuaj uas muaj txiaj ntsig zoo li tshuaj tiv thaiv qaug dab peg. Phenytoin sodium yog sodium ntsev ntawm phenytoin. Qhov sib txawv tseem ceeb ntawm phenytoin thiab phenytoin sodium yog tias phenytoin yog dej-soluble tsawg, whereas phenytoin sodium yog dej-soluble heev.
