Qhov sib txawv tseem ceeb ntawm thrombolysis thiab fibrinolysis yog tias thrombolysis yog kev sib cais ntawm thrombus (ntshav txhaws) vim muaj ntau yam tshuaj thiab lub cev, thaum fibrinolysis yog kev tawg ntawm fibrin hauv cov ntshav txhaws vim yog cov txheej txheem ntuj lossis ntau yam tshuaj. cov agents.
Thrombosis yog tsim cov ntshav txhaws hauv cov hlab ntsha. Nws obstructs kev thauj mus los ntawm cov ntshav los ntawm lub circulatory system. Feem ntau, thaum cov hlab ntsha raug mob, lub cev siv cov platelets thiab fibrin los ua cov hlab ntshav los tiv thaiv cov ntshav ntau dhau. Txawm tias cov hlab ntsha tsis raug mob, cov ntshav txhaws tuaj yeem tshwm sim hauv lub cev hauv qee yam mob. Kev tsis tsim nyog ntawm cov ntshav ntws los ntawm cov ntshav txhaws tuaj yeem ua rau ntau yam kab mob, suav nrog mob stroke. Thrombolysis thiab fibrinolysis yog ob txoj kev siv los rhuav tshem cov ntshav txhaws.
Thrombolysis yog dab tsi?
Thrombolysis yog kev sib cais ntawm cov thrombus (ntshav txhaws) vim muaj ntau yam tshuaj thiab lub cev. Nws tseem hu ua thrombolytic therapy. Nws yog ib qho kev kho tshwj xeeb kom yaj cov ntshav txhaws hauv cov hlab ntsha. Nws txhim kho cov ntshav khiav thiab tiv thaiv kev puas tsuaj rau cov ntaub so ntswg thiab kabmob. Thrombolysis cuam tshuam nrog kev txhaj tshuaj ntawm cov hlab ntsha tawg (cov tshuaj thrombolytic) los ntawm cov kab mob hauv cov hlab ntsha lossis los ntawm cov catheter ntev uas xa cov tshuaj ncaj qha mus rau qhov chaw ntawm cov ntshav txhaws kom yaj nws. Thrombolysis kuj tseem yuav koom nrog kev siv lub catheter ntev nrog cov cuab yeej siv kho qhov muag uas tshem tawm cov ntshav txhaws los ntawm lub cev tawg.
Daim duab 01: Thrombolysis
Thrombolysis tuaj yeem siv los kho cov ntshav txhaws hauv cov hlab ntsha, cov hlab ntsha, hla kev grafts, thiab lim ntshav catheters. Feem ntau cov thrombolytic agents tsom fibrin hauv cov ntshav txhaws, yog li lawv hu ua fibrinolytics. Tissue plasminogen activator (tPA) yog cov tshuaj uas hloov plasminogen rau plasmin. Plasmin yog ib qho endogenous fibrinolytic enzyme uas rhuav tshem cov kab sib txuas hauv ib qho fibrin mesh. Yog li, recombinant cov ntaub so ntswg plasminogen activators xws li alteplase, reteplase, thiab tenecteplase tuaj yeem siv los ua cov tshuaj thrombolytic. Lwm cov tshuaj thrombolytic uas siv tib lub tswv yim saum toj no yog streptokinase thiab urokinase. Cov kws kho mob qee zaum tuaj yeem xaiv tawm rau lwm hom thrombolysis txheej txheem hu ua mechanical thrombectomy. Nyob rau hauv cov txheej txheem no, ib tug ntev catheter tipped nrog ib tug me me nqus khob, rotating ntaus ntawv, thiab ib tug high-ceev kua dav hlau (los yog ultrasound ntaus ntawv) yog siv rau lub cev yaj cov ntshav txhaws nyob rau hauv cov hlab ntsha.
Fibrinolysis yog dab tsi?
Fibrinolysis yog kev tawg ntawm fibrin hauv cov ntshav txhaws vim muaj ntau yam tshuaj lom neeg. Nws tuaj yeem ua rau ob txoj hauv kev: thawj thiab theem nrab. Primary fibrinolysis yog ib qho txheej txheem ntawm lub cev uas tshwm sim ib txwm muaj. Txawm li cas los xij, nyob rau hauv theem nrab fibrinolysis, cov ntshav khov yaj vim yog tus neeg sawv cev tshuaj.
Daim duab 02: Fibrinolysis
Nyob rau hauv fibrinolysis, fibrin hauv cov ntshav txhaws (cov khoom ntawm coagulation) tawg. Lub ntsiab enzyme uas ua haujlwm no yog plasmin. Tissue plasminogen activator (tPA) thiab urokinase (upA) hloov plasminogen rau plasmin. Tom qab ntawd, cov plasmin enzyme txiav cov fibrin mesh ntawm ntau qhov chaw, ua rau kev tsim cov khoom tawg hu ua fibrin degradation products (FDPs). FDPs sib tw nrog thrombin thiab ua rau cov ntshav txhaws qeeb los ntawm kev tiv thaiv kev hloov pauv ntawm fibrinogen rau fibrin. FDPs raug tshem tawm los ntawm lwm cov proteases lossis los ntawm lub raum thiab lub siab. Ntxiv mus, streptokinase, anisoylated plasminogen streptokinase activator complex, urokinase, thiab recombinant tib neeg cov ntaub so ntswg-hom plasminogen activator yog cov piv txwv zoo ntawm cov tshuaj uas ua rau fibrin tawg hauv cov ntshav txhaws..
Dab tsi zoo sib xws ntawm Thrombolysis thiab Fibrinolysis?
- Thrombolysis thiab fibrinolysis yog ob lub tswv yim uas ua rau cov ntshav txhaws.
- Ob lub tswv yim siv tau cov tshuaj tua kab mob los ua kom cov ntshav txhaws.
- Ob lub tswv yim tuaj yeem txhim kho cov ntshav khiav thiab tiv thaiv kev puas tsuaj rau cov ntaub so ntswg thiab lub cev.
- Lawv siv los kho cov kab mob plawv.
- Aminocaproic acid thiab tranexamic acid yog siv los cuam tshuam ob txoj haujlwm.
Qhov txawv ntawm Thrombolysis thiab Fibrinolysis yog dab tsi?
Thrombolysis yog kev sib cais ntawm thrombus (cov ntshav txhaws) vim muaj ntau yam tshuaj thiab lub cev, thaum fibrinolysis yog kev tawg ntawm fibrin hauv cov ntshav txhaws vim yog cov txheej txheem ntuj lossis ntau yam tshuaj. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm thrombolysis thiab fibrinolysis. Tsis tas li ntawd, cov txheej txheem ntawm thrombolysis suav nrog ob qho tib si fibrin tawg hauv cov ntshav txhaws thiab kev tshem tawm cov ntshav txhaws los ntawm cov hlab ntsha. Ntawm qhov tod tes, cov txheej txheem ntawm fibrinolysis tsuas yog cuam tshuam fibrin hauv cov ntshav txhaws.
Cov hauv qab no qhia txog qhov sib txawv ntawm thrombolysis thiab fibrinolysis hauv daim ntawv tabular rau ib sab ntawm kev sib piv.
Summary – Thrombolysis vs Fibrinolysis
ntshav txhaws tuaj yeem tshwm sim vim cov hlab ntsha raug mob lossis lwm yam mob. Thrombolysis thiab fibrinolysis yog ob txoj hauv kev uas tuaj yeem ua rau cov ntshav txhaws hauv cov hlab ntsha. Thrombolysis yog cov txheej txheem ntawm kev tawg ntawm thrombus (cov ntshav txhaws) vim muaj ntau yam tshuaj thiab lub cev, thaum fibrinolysis yog cov txheej txheem ntawm kev tawg ntawm fibrin hauv cov ntshav txhaws vim yog cov txheej txheem ntuj lossis ntau yam tshuaj. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm thrombolysis thiab fibrinolysis.
