Qhov sib txawv tseem ceeb ntawm isosorbide mononitrate thiab isosorbide dinitrate yog tias isosorbide mononitrate feem ntau yog siv rau hauv kev tswj cov mob angina nyob ntev, hos isosorbide dinitrate tau pom zoo rau lub plawv tsis ua haujlwm.
Isosorbide mononitrate thiab isosorbide dinitrate yog cov tshuaj tseem ceeb rau qee yam kab mob plawv. Lawv txawv ntawm ib leeg raws li lawv daim ntawv thov thiab cov khoom.
Isosorbide Mononitrate yog dab tsi?
Y Isosorbide mononitrate yog ib yam tshuaj tseem ceeb hauv kev kho mob plawv mob hauv siab, plawv tsis ua hauj lwm, thiab esophagal spasms. Cov npe nrov tshaj plaws ntawm cov tshuaj no yog "Monoket" thiab "Imdur". Txoj kev tseem ceeb ntawm kev tswj hwm rau cov tshuaj no yog kev tswj hwm qhov ncauj. Raws li cov ntaub ntawv pharmacokinetic, isosorbide mononitrate muaj bioavailability ntawm li 95%, thiab nws cov protein khi muaj peev xwm yog li 5%. Cov metabolism hauv cov tshuaj no tshwm sim hauv daim siab, thiab tshem tawm ib nrab-lub neej yog li 5 teev. Kev tso tawm ntawm isosorbide mononitrate tshwm sim los ntawm lub raum.
Daim duab 01: Cov qauv tshuaj ntawm Isosorbide Mononitrate
Peb tuaj yeem siv cov tshuaj no los kho thiab tiv thaiv kev mob plawv. Tab sis nws tsis nyiam dua piv rau beta-blockers lossis calcium channel blockers.
Muaj qee qhov kev mob tshwm sim ntawm kev siv cov tshuaj no, uas suav nrog mob taub hau, ntshav siab, tsis pom kev, thiab tawv nqaij. Tsis tas li ntawd, tuaj yeem muaj qee qhov cuam tshuam loj heev, uas suav nrog ntshav siab thaum raug PDE5 inhibitors, piv txwv li. Silenafil.
Isosorbide Dinitrate yog dab tsi?
Isosorbide dinitrate yog ib qho tshuaj tseem ceeb hauv kev kho mob plawv tsis ua hauj lwm, oesophagal spasms, thiab kho mob hauv siab uas los ntawm cov ntshav tsis txaus mus rau lub plawv. Cov tshuaj no tshwj xeeb yog siv rau hauv lub plawv tsis ua hauj lwm vim lub peev xwm ntawm systolic tsis ua hauj lwm ua ke nrog hydralazine. Txoj kev ntawm kev tswj hwm cov tshuaj no yog qhov ncauj, tab sis nws tuaj yeem noj hauv qab tus nplaig thiab.
Daim duab 02: Cov Qauv Tshuaj ntawm Isosorbide Dinitrate
Cov kev mob tshwm sim feem ntau ntawm isosorbide dinitrate muaj xws li mob taub hau, tsis pom kev thaum sawv ntsug, thiab qhov muag tsis pom kev. Nws tuaj yeem muaj qee qhov kev mob tshwm sim hnyav, xws li ntshav siab. Lub npe lag luam ntawm cov tshuaj no yog "Isordil".
Raws li cov ntaub ntawv pharmacokinetic, bioavailability ntawm cov tshuaj no yog kwv yees li 25% ntawm qhov nruab nrab, thiab nws cov metabolism tshwm sim hauv daim siab. Kev tshem tawm ib nrab-lub neej ntawm isosorbide dinitrate yog kwv yees li 1 teev, thiab qhov tso tawm tshwm sim los ntawm lub raum.
Ntxiv rau lwm cov tshuaj uas tau muab rau lub plawv tsis ua haujlwm, isosorbide dinitrate muaj txiaj ntsig zoo hauv kev kho mob angina. Cov tshuaj no yog muag nyob rau hauv ob daim ntawv: raws li ib tug ntsiav tshuaj ntawm qhov ncauj ob qho tib si nyob rau hauv ncua-tso tawm thiab qeeb tso tawm.
Qhov txawv ntawm Isosorbide Mononitrate thiab Isosorbide Dinitrate yog dab tsi?
Isosorbide mononitrate txawv ntawm isosorbide dinitrate raws li tus naj npawb ntawm nitro pawg ib molecule. Qhov sib txawv tseem ceeb ntawm isosorbide mononitrate thiab isosorbide dinitrate yog tias isosorbide mononitrate feem ntau yog siv los tswj cov mob angina nyob ntev, hos isosorbide dinitrate tau pom zoo rau lub plawv tsis ua haujlwm.
Ntxiv mus, isosorbide mononitrate muaj bioavailability txog li 95% thaum isosorbide dinitrate muaj bioavailability txog li 25%. Tsis tas li ntawd, lub sij hawm tshem tawm ntawm isosorbide mononitrate yog li 5 teev thaum lub sij hawm tshem tawm ntawm isosorbide dinitrate yog 1 teev.
Cov infographic hauv qab no nthuav tawm qhov sib txawv ntawm isosorbide mononitrate thiab isosorbide dinitrate hauv daim ntawv tabular rau ib sab ntawm kev sib piv.
Summary – Isosorbide Mononitrate vs Isosorbide Dinitrate
Isosorbide mononitrate thiab isosorbide dinitrate yog cov tshuaj tseem ceeb rau qee yam kab mob plawv. Lawv txawv ntawm ib leeg raws li lawv daim ntawv thov thiab cov khoom. Qhov sib txawv tseem ceeb ntawm isosorbide mononitrate thiab isosorbide dinitrate yog tias isosorbide mononitrate feem ntau yog siv los tswj cov mob angina nyob ntev, hos isosorbide dinitrate tau pom zoo rau lub plawv tsis ua haujlwm.
