Qhov sib txawv tseem ceeb ntawm PCV13 thiab PPSV23 yog qhov PCV13 (13-valent pneumococcal conjugate vaccine) yog tshuaj tiv thaiv kab mob ntsws uas muaj 13 antigens los ntawm cov kab mob sib txawv, thaum PPSV23 (23-valent pneumococcal polysaccharide vaccine tiv thaiv) mob ntsws uas muaj 23 antigens los ntawm cov serotypes.
Pneumonia yog kab mob ua pa uas ua rau muaj kev mob hnyav thiab tuag hauv ntiaj teb. Streptococcus pneumoniae kab mob yog cov kab mob uas feem ntau pom tias ua rau mob ntsws hauv zej zog. Hauv Tebchaws Meskas, S. pneumoniae yog lub luag haujlwm rau 500, 000 tus neeg mob ntsws thiab 50,000 tus neeg mob bacteremia txhua xyoo. Ntxiv nrog rau kev txhawj xeeb txog kev noj qab haus huv rau pej xeem, mob ntsws kuj tseem ua rau tus nqi loj rau kev kho mob. Tam sim no muaj ob hom tshuaj tiv thaiv kab mob S. pneumoniae. Ob qhov tshuaj tiv thaiv no yog PCV13 thiab PPSV23.
PCV13 yog dab tsi?
PCV13 (13-valent pneumococcal conjugate vaccine) yog tshuaj tiv thaiv kab mob ntsws uas tshwm sim los ntawm Streptococcus pneumonia. Cov tshuaj tiv thaiv no muaj 13 antigens los ntawm cov serotypes. Lwm lub npe rau PCV13 yog Prevnar 13. Nws yog ib qho tshuaj tiv thaiv kab mob uas ib txwm siv los tiv thaiv cov menyuam mos, menyuam yaus, thiab cov neeg laus tiv thaiv kev mob ntsws los ntawm cov kab mob Streptococcus pneumoniae. Nws muaj purified capsular polysaccharides ntawm pneumococcal serotypes conjugated mus rau ib tug carrier protein. Feem ntau cov kab mob no yog cov kab mob diphtheria carrier protein. Qhov kev sib txuas no txhim kho cov tshuaj tiv thaiv kab mob.
Daim duab 01: PCV13
Lub koom haum saib xyuas kev noj qab haus huv hauv ntiaj teb pom zoo cov tshuaj tiv thaiv kab mob sib xyaw ua ke hauv kev txhaj tshuaj txhua hnub rau menyuam yaus. Ntxiv mus, cov tshuaj tiv thaiv PCV13 conjugate no yog tsim los ntawm Pfizer (yav tas los Wyeth) tuam txhab. Kaum peb serotypes ntawm pneumococcus hauv cov tshuaj tiv thaiv no yog 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F thiab 23F. PCV 13 tau pom zoo los ntawm European Union thaum Lub Kaum Ob Hlis 2009. Lub Ob Hlis 2010, nws tau pom zoo hauv Tebchaws Meskas los hloov cov tshuaj tiv thaiv kab mob pneumococcal 7-valent conjugate.
Cov kev mob tshwm sim ntawm cov tshuaj tiv thaiv no yog liab, o, mob, rhiab thaum txhaj tshuaj, ua npaws, tsis qab los noj mov, fussiness, nkees, mob taub hau, ua daus no, thiab lwm yam. Tsis tas li ntawd, cov neeg mob yuav tsum hu rau tus kws kho mob tam sim ntawd. rau kev tsis haum tshuaj loj tom qab txhaj tshuaj tiv thaiv kab mob sib xyaw ua ke.
PPSV23 yog dab tsi?
PPSV23 (23-valent pneumococcal polysaccharide vaccine) yog tshuaj tiv thaiv kab mob ntsws los ntawm Streptococcus pneumonia. Cov tshuaj tiv thaiv polysaccharide no muaj 23 antigens los ntawm ntau hom serotypes. PPSV23 tuaj yeem tiv thaiv kab mob pneumococcal zoo ib yam li cov tshuaj tiv thaiv PCV13. Ntxiv nrog rau kev mob ntsws, PPSV23 tuaj yeem tiv thaiv pob ntseg, kab mob sinus, meningitis thiab bacteremia.
Daim duab 02: PPSV23
PPSV23 raug pom zoo rau txhua tus neeg laus 65 xyoo lossis tshaj saud thiab txhua tus 2 xyoos lossis tshaj saud nrog qee yam mob. Feem ntau, PPSV23 muab kev tiv thaiv 23 hom kab mob uas ua rau muaj kab mob pneumococcal. PPSV23 tseem ceeb heev rau cov neeg mob HIV/AIDS. Cov serotypes uas muaj nyob rau hauv cov tshuaj tiv thaiv yog 1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19F, 19A, 20,222,,33f ib. Cov tshuaj tiv thaiv no kuj tuaj yeem muab cov kev mob tshwm sim xws li liab, mob, lossis mob qhov chaw txhaj tshuaj, nkees, tsis muaj zog, o los yog tuab ntawm qhov chaw txhaj tshuaj, ua npaws, mob nqaij thiab ua xua hnyav, thiab lwm yam.
Qhov Zoo sib xws ntawm PCV13 thiab PPSV23 yog dab tsi?
- PCV13 thiab PPSV23 yog ob hom tshuaj tiv thaiv kab mob uas tiv thaiv tus kab mob pneumoniae.
- Ob qho tshuaj tiv thaiv muaj cov tshuaj capsular polysaccharides ntawm pneumococcal serotypes.
- Cov tshuaj tiv thaiv no kho tus kab mob pneumococcal.
- Ob koob tshuaj tiv thaiv kab mob pob ntseg, kab mob sinus, meningitis, bacteremia, ntxiv rau kev mob ntsws.
- Kaum ob ntawm kaum peb serotypes suav nrog hauv PCV13 muaj ntau rau PPSV23.
Qhov txawv ntawm PCV13 thiab PPSV23 yog dab tsi?
PCV13 yog tshuaj tiv thaiv kab mob ntsws uas muaj 13 antigens los ntawm cov kab mob sib xws, thaum PPSV23 yog tshuaj tiv thaiv kab mob ntsws uas muaj 23 antigens los ntawm cov kab mob sib xws. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm PCV13 thiab PPSV23. Tsis tas li ntawd, PCV13 npog cov kab mob pneumococcal tsawg dua tab sis tuaj yeem ua rau muaj kev tiv thaiv kab mob ntev, thaum PPSV23 npog cov kab mob pneumococcal ntau dua tab sis yuav tsis ua rau muaj kev tiv thaiv ntev ntev.
Cov hauv qab no infographic teev qhov sib txawv ntawm PCV13 thiab PPSV23 hauv daim ntawv teev npe rau ib sab ntawm kev sib piv.
Summary – PCV13 vs PPSV23
Streptococcus pneumoniae yog cov kab mob feem ntau pom tias ua rau mob ntsws hauv zej zog. Tam sim no muaj ob hom tshuaj tiv thaiv kab mob S. pneumoniae. Lawv yog PCV13 thiab PPSV23. PCV13 tiv thaiv 13 hom kab mob Streptococcus pneumoniae uas ua rau cov kab mob pneumococcal, thaum PPSV23 tiv thaiv 23 hom kab mob Streptococcus pneumoniae uas ua rau cov kab mob pneumococcal. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm PCV13 thiab PPSV23.
