Qhov sib txawv tseem ceeb ntawm dystrophic thiab metastatic calcification yog tias dystrophic calcification yog qhov tso cov calcium ntsev hauv cov ntaub so ntswg tuag los yog degenerated, thaum metastatic calcification yog cov deposition ntawm calcium ntsev nyob rau hauv ib txwm cov ntaub so ntswg.
Calcification yog kev sib sau ntawm calcium ntsev hauv lub cev nqaij daim tawv. Feem ntau nws tshwm sim hauv kev tsim cov pob txha. Tab sis calcium kuj tuaj yeem tso tawm txawv txav hauv cov ntaub so ntswg. Raws li seb puas muaj cov ntxhia sib npaug lossis tsis, calcifications yuav raug faib ua ob hom: dystrophic thiab metastatic calcification. Qhov no tseem hu ua pathologic calcification, vim nws yog qhov txawv txav ntawm calcium ntsev hauv cov ntaub so ntswg uas tsis yog osteoid lossis enamel. Dystrophic calcification tshwm sim yam tsis muaj qhov tsis txaus ntawm cov ntxhia hauv lub cev, thaum metastatic calcification tshwm sim vim qhov nce siab ntawm calcium hauv cov ntshav thiab tag nrho cov ntaub so ntswg.
Dystrophic Calcification yog dab tsi?
Dystrophic calcification yog qhov tso ntawm calcium ntsev hauv cov ntaub so ntswg tuag lossis degenerated. Nws feem ntau tshwm sim hauv cov ntaub so ntswg necrotic xws li hyalinized nti, degenerated foci hauv leiomyomas, thiab caseous nodules. Nws tshwm sim los ntawm qhov tshwm sim ntawm cov tshuaj tiv thaiv rau cov ntaub so ntswg puas tsuaj thiab raws li ib tug tshwm sim ntawm kev kho mob implantation. Txawm hais tias cov calcium hauv cov ntshav tsis nce siab, dystrophic calcification tuaj yeem tshwm sim. Yog li ntawd, nyob rau hauv cov ntaub ntawv ntawm dystrophic calcification, plasma calcium thiab phosphate theem yog ib txwm.
Daim duab 01: Dystrophic Calcification
Nyob rau hauv dystrophic calcification, deposition ntawm calcium tshwm sim nyob rau hauv ob theem: pib theem thiab propagation theem. Cov theem pib ntxiv faib ua intracellular thiab extracellular. Nyob rau hauv intracellular pib, lub cell puas muaj ib tug ntau ntawm cov calcium nkag mus rau hauv lub cytoplasm. Cov calcium uas tau nkag mus muaj kev sib raug zoo rau mitochondria thiab tau tso rau hauv mitochondria. Nyob rau hauv lub extracellular pib theem, lub degenerated cell muaj membrane-bound vesicles uas muaj acidic phospholipids. Calcium muaj kev sib raug zoo rau cov kua qaub phospholipids thiab yog li tso rau hauv vesicles. Phosphates kuj sau nyob rau hauv tib lub vesicles. Thaum calcium thiab phosphate accumulates nyob rau hauv cov hlab ntsha, lawv tau budded tawm ntawm lub cell. Tsis tas li ntawd, calcium deposition tshwm sim nyob rau hauv lub propagation theem. Qhov no yog vim muaj cov protein hu ua osteopontin. Hauv dystrophic calcification, osteopontin muaj nyob rau hauv ntau. Qhov no ua rau calcification ntawm cov ntaub so ntswg tuag los yog degenerated.
Metastatic Calcification yog dab tsi?
Metastatic calcification yog qhov tso ntawm calcium ntsev hauv cov ntaub so ntswg. Qhov no yog vim qhov nce qib ntawm calcium hauv cov ntshav. Kev nce qib ntawm calcium nyob rau hauv cov ntshav tshwm sim vim yog deranged metabolism, nce nqus, los yog txo excretion ntawm calcium thiab lwm yam minerals. Qhov xwm txheej no tuaj yeem pom hauv hyperparathyroidism. Nws yog lub npe hu ua metastatic calcification vim calcium los ntawm cov pob txha txav tawm thiab tso rau hauv cov ntaub so ntswg deb.
Daim duab 02: Metastatic Calcification
Metastatic calcification tuaj yeem tshwm sim thoob plaws hauv lub cev. Tab sis qhov tseem ceeb, nws cuam tshuam rau cov ntaub so ntswg interstitial ntawm vasculature, ob lub raum, ntsws, thiab gastric mucosa. Qhov laj thawj tseem ceeb ntawm metastatic calcification yog hyperparathyroidism, resorption ntawm cov pob txha cov ntaub so ntswg, tsis zoo ntawm vitamin D, thiab lub raum tsis ua hauj lwm. Tseem muaj lwm yam ua rau lwm yam xws li kev qaug tshuaj txhuas hauv cov neeg mob uas mob raum lim ntshav thiab mis-alkali syndrome vim noj mis ntau dhau.
Dab tsi yog qhov zoo sib xws ntawm Dystrophic thiab Metastatic Calcification?
- Ob nqe lus muaj feem cuam tshuam rau calcification.
- Lawv yog hom kab mob calcifications.
- Ob leeg yog hom calcification, uas muaj calcium phosphate crystals.
- Lawv tshwm sim hauv lub cev nqaij daim tawv.
Qhov txawv ntawm Dystrophic thiab Metastatic Calcification yog dab tsi?
Dystrophic calcification yog qhov tso ntawm calcium ntsev hauv cov ntaub so ntswg tuag lossis degenerated. Ntawm qhov tod tes, metastatic calcification yog tso cov calcium ntsev hauv cov ntaub so ntswg. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm dystrophic thiab metastatic calcification. Tsis tas li ntawd, nyob rau hauv cov ntaub ntawv ntawm dystrophic calcification, serum calcium theem yog ib txwm, tab sis nyob rau hauv metastatic calcification, cov qib calcium hauv cov ntshav nce siab.
Cov infographic hauv qab no nthuav tawm qhov sib txawv ntawm dystrophic thiab metastatic calcification hauv daim ntawv.
Summary – Dystrophic vs Metastatic Calcification
Pathological calcification yog qhov txawv txav ntawm calcium ntsev hauv cov ntaub so ntswg uas tsis yog osteoid lossis enamel. Pathological calcification yog muab faib ua dystrophic thiab metastatic calcification. Ob hom calcifications muaj calcium phosphate crystals. Txawm li cas los xij, qhov sib txawv loj ntawm dystrophic thiab metastatic calcification yog tias dystrophic calcification tshwm sim hauv cov ntaub so ntswg puas, thaum metastatic calcification tshwm sim hauv cov ntaub so ntswg.
