Qhov Tseem Ceeb - Ischemia vs Infarction
Muaj yam tseem ceeb xws li oxygen thiab qabzib xav tau los ntawm cov hlwb rau lawv txoj sia. Thaum cov metabolites tsis txaus nkag mus rau pathological cellular hloov pauv pib tshwm sim hauv cov hlwb thiab yog tias tsis kho cellular tuag. Ischemia thiab infarction yog ob yam txheej txheem uas yog vim tsis muaj cov khoom tseem ceeb hauv cov hlwb. Mechanical obstruction ntawm cov hlab ntsha uas ua rau hypoxia uas yog lub hauv paus rau ischemia. Kev puas tsuaj ntawm cov kua dej venous tuaj yeem ua rau cov ntaub so ntswg puas. Infarction yog tus txheej txheem uas ib cheeb tsam ntawm ischemic necrosis yog tsim los ntawm ib qho hlab ntsha occlusion los yog ib qho kev cuam tshuam rau lub venous kua. Qhov sib txawv tseem ceeb ntawm ischemia thiab infarction yog necrosis tshwm sim tsuas yog hauv infarction thiab tsis yog hauv ischemia.
Ischemia yog dab tsi?
Ischemia yog hom kev raug mob ntawm tes ntau tshaj plaws hauv cov tshuaj. Mechanical obstruction ntawm cov hlab ntsha uas ua rau hypoxia yog lub hauv paus rau ischemia. Kev puas tsuaj ntawm cov kua dej venous tuaj yeem ua rau cov ntaub so ntswg puas. Tsis zoo li hauv hypoxia qhov twg lub zog tsim tawm tuaj yeem tshwm sim los ntawm kev ua pa anaerobic, hauv ischemia cov khoom ntawm cov substrates rau glycolysis tsis tshwm sim. Yog li ntawd, tsis muaj oxygen tsis txaus, tab sis kuj muaj lub zog tsis muaj zog. Yog li, muaj kev raug mob ntawm tes sai hauv ischemia dua li hauv hypoxia, uas tsis cuam tshuam nrog ischemia.
Mechanism ntawm Ischemia
Vim tsis muaj oxygen, oxidative phosphorylation tsis tshwm sim. Nyob rau tib lub sijhawm, glycolysis yog inhibited los ntawm qhov tsis muaj substrates. Yog li ntawd, tsis muaj ATP txaus rau kev saib xyuas ntawm cov twj tso kua mis cellular ion. Qhov no ua rau muaj qhov tsis txaus ntawm electrolyte hauv lub cell.
Cellular hloov pauv cuam tshuam nrog ischemia
- Dispersion ntawm cytoskeleton thiab tsim cov blebs
- Pom cov duab myelin hauv cov hlwb los ntawm cov cellular degenerating
- o ntawm mitochondria
- Dilation of ER
Cov kev hloov pauv no rov qab yog tias qhov hypoxia raug kho li ntawm 30-40 feeb txij li qhov pib ntawm ischemia.
Daim duab 01: Ischemia hauv qis qis
Cell tuag hauv ischemia feem ntau tshwm sim los ntawm kev ua kom apoptotic txoj hauv kev thiab necrosis. Cellular organelles zuj zus degenerate, thiab muaj efflux ntawm cellular enzymes mus rau hauv lub extracellular qhov chaw. Extracellular macromolecules pib nkag mus rau hauv lub cell. Thaum kawg cov cell tuag tau hloov los ntawm myelin cov duab uas muaj phospholipids.
Kev mob plab yog dab tsi?
Infarction yog tus txheej txheem los ntawm qhov chaw ntawm ischemic necrosis yog tsim los ntawm cov hlab ntsha occlusion lossis cuam tshuam rau cov kua dej.
Cas of Infarction
- Arterial thrombosis thiab embolism
- Hemorrhage into a atheromatous plaque
- Txoj hlab ntsha los ntawm qog
- Txawm hais tias venous ob leeg tuaj yeem ua rau muaj kev cuam tshuam, feem ntau nws xaus rau qhov congestion tshwj xeeb tshaj yog cuam tshuam rau cov hlab ntsha uas tsuas muaj ib txoj hlab ntsha xwb.
Red Infarcts
Tshuaj nrog venous occlusion nyob rau hauv xoob, spongy ntaub so ntswg, nyob rau hauv cov ntaub so ntswg nrog ib tug ob chav ncig thiab nyob rau hauv cov ntaub so ntswg uas muaj congested network ntawm cov leeg.
Dawb Infarcts
Cov no tshwm sim vim muaj cov hlab ntsha tawg hauv cov khoom nruab nrog cev nrog qhov kawg ntawm cov hlab ntsha.
Septic Infarcts
Lub colonization ntawm microbes nyob rau hauv cov ntaub so ntswg necrosed forms Septic infarcts.
Yam cuam tshuam rau Kev Tsim Cov Kab Mob
- Kev xav ntawm vascular mov ntawm cheeb tsam cuam tshuam
- Tus nqi ntawm occlusion
- Cov ntaub so ntswg qhov tsis zoo rau hypoxia
- hypoxemia
Daim duab 02: Infarction
Kev mob hauv yuav luag txhua lub cev ntawm lub cev tsuas yog hauv lub hlwb ua rau coagulative necrosis. Hauv lub hlwb, kev ua txhaum cai ua rau muaj liquefactive necrosis.
Dab tsi zoo sib xws ntawm Ischemia thiab Infarction?
- Cov ntaub so ntswg puas tshwm sim rau ob lub sijhawm
- Hypoxia yog qhov tshwm sim ntawm ob qho tib si ischemia thiab infarction
Qhov txawv ntawm Ischemia thiab Infarction yog dab tsi?
Ischemia vs Infarction |
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| Ischemia yog hom kev raug mob ntawm tes ntau tshaj plaws hauv cov tshuaj. Mechanical obstruction ntawm cov hlab ntsha uas ua rau hypoxia yog lub hauv paus rau ischemia. Kev puas tsuaj ntawm cov venous kua kuj tuaj yeem ua rau cov ntaub so ntswg puas. | Infarction yog tus txheej txheem los ntawm qhov chaw ntawm ischemic necrosis yog tsim los ntawm cov hlab ntsha occlusion lossis cuam tshuam rau cov kua dej. |
| Necrosis | |
| Necrosis tsis tshwm sim. | Necrosis tshwm sim. |
Summary – Ischemia vs Infarction
Ischemia yog hom kev raug mob ntawm tes ntau tshaj plaws hauv cov tshuaj. Mechanical obstruction ntawm cov hlab ntsha uas ua rau hypoxia yog lub hauv paus rau ischemia. Kev puas tsuaj ntawm cov kua dej venous tuaj yeem ua rau cov ntaub so ntswg puas. Ntawm qhov tod tes, infarction tuaj yeem txhais tau tias yog tus txheej txheem los ntawm qhov chaw ntawm ischemic necrosis yog tsim los ntawm cov hlab ntsha occlusion lossis kev cuam tshuam rau cov kua dej. Qhov sib txawv ntawm cov txheej txheem pathological no yog cov ntaub so ntswg necrosis tshwm sim tsuas yog hauv infarction thiab tsis yog hauv ischemia.
Download the PDF Version of Ischemia vs Infarction
Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline hom phiaj raws li daim ntawv ceeb toom. Thov download PDF version ntawm no Qhov txawv Ntawm Ischemia thiab Infarction
