Qhov txawv ntawm Ketosis thiab Ketogenesis

Cov txheej txheem:

Qhov txawv ntawm Ketosis thiab Ketogenesis
Qhov txawv ntawm Ketosis thiab Ketogenesis

Video: Qhov txawv ntawm Ketosis thiab Ketogenesis

Video: Qhov txawv ntawm Ketosis thiab Ketogenesis
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Qhov sib txawv tseem ceeb ntawm ketosis thiab ketogenesis yog tias ketosis yog lub xeev metabolic uas qhia txog qib ketone lub cev hauv cov ntshav lossis zis, thaum ketogenesis yog cov txheej txheem biochemical uas cov kab mob tsim cov ketone lub cev los ntawm kev rhuav tshem cov roj fatty acids thiab ketogenic. Cov amino acids.

Eukaryotic hlwb ua lub zog los ntawm cov txheej txheem sib txawv xws li photosynthesis, glycolysis, citric acid voj voog thiab oxidative phosphorylation. Cov txheej txheem no ua rau muaj zog-nplua nuj molecules zoo li ATP thiab NADH. Cov kab mob tau txais ntau qhov chaw xws li tshav ntuj ncaj qha, CO 2thiab cov khoom noj khoom haus organic, thiab lwm yam, los ntawm ib puag ncig txhawm rau tsim lub zog. Ketosis thiab ketogenesis yog ob txheej txheem ntsig txog kev tsim hluav taws xob hauv hlwb.

Ketosis yog dab tsi?

Ketosis yog ib qho mob ntawm lub cev uas yog tus cwj pwm los ntawm cov ntshav ketone siab thiab cov ntshav qabzib ib txwm. Hauv qhov xwm txheej no, ntshav pH kuj tseem nyob li qub. Kev tsim cov ketone lub cev ntau ntxiv hauv lub cev yog vim muaj cov piam thaj tsawg. Yog li ntawd, kev nce hauv kev tsim cov ketone lub cev ua rau lub zog hloov pauv rau lub hlwb. Cov mob no tuaj yeem yog los ntawm kev noj zaub mov tsawg-carbohydrate lossis yoo mov. Thaum physiologic ketoacidosis yog tshwm sim los ntawm kev txwv tsis pub noj cov zaub mov carbohydrate (cov khoom noj ketogenic), qee zaum hu ua khoom noj khoom haus ketosis. Hauv ketosis, cov qib ketone hauv cov ntshav feem ntau nyob qis dua 3 mM.

Qhov sib txawv ntawm Ketosis thiab Ketogenesis
Qhov sib txawv ntawm Ketosis thiab Ketogenesis

Daim duab 01: Ketosis

Ketogenic noj zaub mov tuaj yeem pab poob phaus. Hauv luv luv, nws poob phaus sai heev vim nws txo lub cev cov khw muag khoom ntawm glycogen thiab dej. Nyob rau hauv lub sij hawm ntev, ketogenic noj cov zaub mov suppress qab los noj mov, ua rau kom tsawg-calorie kom tsawg. Qee zaum, ketosis muaj ntau yam txiaj ntsig kev noj qab haus huv, xws li txo qis qaug dab peg hauv cov menyuam yaus uas muaj mob vwm. Cov tshuaj hauv khw muag khoom tau tshaj tawm tias yuav nce qib ketone hauv lub cev, thiab lawv tuaj yeem ua tshuaj, hmoov, roj, thiab lwm yam ntaub ntawv. Nyob rau hauv ketosis, lub siab sai sai zom cov fatty acids rau hauv acetyl-CoA. Cov acetyl-CoA molecules tuaj yeem hloov mus rau hauv ketone lub cev xws li acetoacetate, beta-hydroxybutyrate, thiab acetone, thiab lwm yam.

Ketogenesis yog dab tsi?

Ketogenesis yog txheej txheem biochemical. Cov kab mob tsim cov ketone lub cev los ntawm kev rhuav tshem cov fatty acids thiab ketogenic amino acids. Cov txheej txheem no muab lub zog rau qee yam kabmob xws li lub hlwb, lub plawv thiab cov leeg pob txha. Cov txheej txheem no txawm siv qhov chaw nyob rau hauv cov xwm txheej tshwj xeeb, suav nrog kev yoo mov, kev txwv caloric, pw tsaug zog, lossis lwm yam. Gluconeogenesis tsis txaus ua rau ntau dhau ntawm ketogenesis thiab hypoglycemia. Thaum kawg nws ua rau muaj kev phom sij rau lub neej hu ua non-diabetic ketoacidosis.

Qhov txawv tseem ceeb - Ketosis vs Ketogenesis
Qhov txawv tseem ceeb - Ketosis vs Ketogenesis

Daim duab 02: Ketogenesis

Ketone lub cev tsis yog tsim los ntawm fatty acids. Ib qho txiaj ntsig ntawm ketone lub cev yog tsim los tsuas yog nyob rau hauv cov xwm txheej ntawm cov carbohydrates thiab cov protein tsis txaus, qhov twg tsuas yog cov roj fatty acids tau yooj yim los ua roj rau ketone lub cev tsim. Ketogenesis tas li tshwm sim hauv cov tib neeg noj qab haus huv. Cov txheej txheem no yog nyob rau hauv kev tswj hwm ntawm tus thawj tswj hwm cov protein hu ua AMPK. Nws activates lub sij hawm ntawm metabolic kev nyuaj siab, xws li carbohydrate insufficiency. Ethanol yog ib qho muaj zog inhibitor hauv AMPK.

Dab tsi yog qhov zoo sib xws ntawm Ketosis thiab Ketogenesis?

  • Cov txheej txheem no tsim cov ketone lub cev.
  • Ob txheej txheem muaj nyob rau hauv cov xwm txheej xws li txwv tsis pub carbohydrate, yoo mov, kev tawm dag zog ntau dhau, thiab lwm yam.
  • Fatty acids koom rau hauv ob txoj kev.
  • Ob txheej txheem muab lwm lub zog rau lub hlwb.

Qhov txawv ntawm Ketosis thiab Ketogenesis yog dab tsi?

Ketosis yog lub xeev metabolic uas muaj qib siab ntawm ketone lub cev hauv cov ntshav lossis zis. Ntawm qhov tod tes, ketogenesis yog cov txheej txheem biochemical uas cov kab mob tsim ketone lub cev los ntawm kev rhuav tshem cov fatty acids thiab ketogenic amino acids. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm ketosis thiab ketogenesis. Ntxiv mus, lwm qhov sib txawv tseem ceeb ntawm ketosis thiab ketogenesis yog ketosis yog cov txheej txheem metabolic, thaum ketogenesis yog txheej txheem biochemical.

Cov duab hauv qab no qhia ntau qhov sib txawv ntawm ketosis thiab ketogenesis hauv daim ntawv teev npe.

Qhov sib txawv ntawm Ketosis thiab Ketogenesis hauv Tabular Form
Qhov sib txawv ntawm Ketosis thiab Ketogenesis hauv Tabular Form

Summary – Ketosis vs Ketogenesis

Ketosis yog cov txheej txheem metabolic uas lub cev tsim cov ketone lub cev los siv roj los ntawm qee yam kabmob xws li lub hlwb. Nws yog tus cwj pwm los ntawm cov ntshav ketone siab, cov ntshav qabzib ib txwm, thiab cov ntshav pH. Yog li, glycogen tuaj yeem khaws cia rau hauv nruab nrog cev thaum lub sijhawm ua haujlwm xws li yoo mov, tshaib plab, thiab lwm yam. Ketosis kuj tshwm sim thaum ua raws li kev noj zaub mov ketogenic. Hauv ketosis, lub cev acid-base homeostasis yog khaws cia. Hauv qhov sib piv, ketogenesis yog cov txheej txheem biochemical uas cov kab mob tsim cov ketone lub cev los ntawm kev rhuav tshem cov fatty acids thiab ketogenic amino acids. Cov txheej txheem muab lub zog rau qee yam hauv nruab nrog cev raws li cov xwm txheej tshwj xeeb xws li kev yoo mov, kev txwv caloric, pw tsaug zog lossis lwm yam. Kev tsis txaus gluconeogenesis thiab ketogenesis ntau dhau tuaj yeem ua rau tsis muaj ntshav qab zib ketoacidosis. Yog li, qhov no yog cov ntsiab lus ntawm qhov sib txawv ntawm ketosis thiab ketogenesis.

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