Qhov sib txawv tseem ceeb ntawm kev tsim thiab tswj exocytosis yog tias nyob rau hauv cov txheej txheem exocytosis, cov ntaub ntawv zais cia tau tso tawm tsis tu ncua, thaum nyob rau hauv cov txheej txheem exocytosis, cov ntaub ntawv zais cia ruaj khov hauv cov hlab ntsha hauv qhov chaw cia.
Exocytosis yog cov txheej txheem uas cov hlwb tso cov molecules mus rau sab nraud ntawm tes. Los ntawm exocytosis, cov cell thauj cov molecules mus rau plasma membrane thiab ntau lub hlwb kuj tso cov proteins rau cov kua dej ntxiv. Tsis tas li ntawd, cov cell sib txuas lus nrog ib leeg los ntawm ntau yam kev taw qhia cov molecules. Intracellular signaling molecules yog tso tawm los ntawm secretory vesicles. Muaj ob hom exocytosis li constutive exocytosis thiab tswj exocytosis. Cells nqa tawm constitutive exocytosis kom hloov cov molecules los ntawm Golgi network mus rau sab nrauv ntawm tes. Nyob rau hauv constitutive exocytosis, cov ntaub ntawv secretory raug tso tawm tsis tu ncua. Ntawm qhov tod tes, cov hlwb ua cov txheej txheem exocytosis hauv kev teb rau cov xwm txheej tshwj xeeb, cov cim qhia lossis cov tshuaj biochemical. Hauv kev tswj hwm exocytosis, cov ntaub ntawv zais cia raug tso tawm hauv kev tswj hwm zoo rau hauv cov hlab ntsha secretory.
Kev Txhaum Exocytosis yog dab tsi?
Kev sib koom ua ke exocytosis yog ib qho ntawm ob hom exocytosis. Cells nqa tawm cov txheej txheem exocytosis txhawm rau hloov cov molecules los ntawm Golgi network mus rau sab nraud ib puag ncig ntawm tes. Nws yog txoj hauv kev ua ntej ntawm exocytosis, thiab nws yog ib qho tseem ceeb hauv kev thauj cov proteins xws li receptors uas ua haujlwm hauv cov ntshav plasma.
Daim duab 01: Kev Sib Koom Tes vs Kev Cai Exocytosis
Ntxiv mus, nyob rau hauv kev tsim exocytosis, cov ntaub ntawv zais cia raug tso tawm tsis tu ncua. Tus nqi ntawm constitutive exocytosis yog tswj tau zoo. Tus nqi no nyob ntawm lawv tus nqi ntawm kev tsim khoom, uas yog tswj hwm los ntawm kev sau thiab txhais lus. Tab sis tsis zoo li kev tswj hwm exocytosis, cov ntaub ntawv zais cia tsis raug tso tawm raws li kev tswj hwm.
Txoj Cai Exocytosis yog dab tsi?
Regulated exocytosis yog ib daim ntawv tshwj xeeb ntawm exocytosis uas tshwm sim thaum lub xov tooj ntawm tes tau txais lub teeb liab los ntawm sab nraud. Cells nqa tawm tswj exocytosis nyob rau hauv teb rau tej yam kev mob, teeb liab los yog biochemical triggers. Cells tso tawm cov ntaub ntawv raws li kev tswj hwm. Cov ntaub ntawv secretory yog thawj zaug nyob rau hauv secretory vesicles nyob rau hauv tswj exocytosis. Nyob rau hauv txoj kev no, cov hlwb tso tawm cytokines, cov tshuaj hormones, neurotransmitters, neuropeptides thiab lwm yam me me signaling molecules.
Daim duab 02: Kev Cai Exocytosis
Txhim exocytosis tsim lub hauv paus rau ntau yam kev cuam tshuam ntawm lub cev. Muaj ob txoj hauv kev ntawm kev tswj exocytosis. Thawj txoj hauv kev feem ntau zais cov polypeptides thaum txoj kev thib ob feem ntau zais cov tshuaj uas tsis muaj molecular-yuag.
Dab tsi yog qhov zoo sib xws ntawm Kev Tsim Kho thiab Kev Cai Exocytosis?
- Kev tsim thiab tswj cov exocytosis yog ob hom exocytosis.
- Txoj hauv kev tseem ceeb thiab cov txheej txheem yooj yim rau kev tswj hwm thiab tsim cov exocytosis zoo ib yam.
Qhov txawv ntawm Kev Tsim Kho thiab Kev Cai Exocytosis yog dab tsi?
Exocytosis tuaj yeem tsim lossis tswj tau. Nyob rau hauv constitutive exocytosis, cov ntaub ntawv secretory raug tso tawm tsis tu ncua. Tab sis, nyob rau hauv kev tswj exocytosis, cov ntaub ntawv secretory raug tso rau hauv secretory vesicles ntawm-xav tau los ntawm secretagogues thiab teeb liab transduction. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm kev tsim thiab tswj exocytosis.
Ntau qhov sib txawv ntawm kev tsim thiab tswj exocytosis tau pom nyob rau hauv daim ntawv teev npe hauv qab no infographic.
Summary – Constitutive vs Regulated Exocytosis
Kev tsim kho thiab tswj hwm exocytosis yog ob hom exocytosis. Nyob rau hauv constitutive exocytosis, cov ntaub ntawv secretory raug tso tawm tsis tu ncua. Secretagogue los yog cia vesicles tsis koom nrog. Nws yog ib qho tseem ceeb hauv kev thauj cov proteins xws li receptors uas ua haujlwm hauv plasma membrane. Ntawm qhov tod tes, tswj exocytosis tshwm sim nyob rau hauv kev tswj hwm. Cov ntaub ntawv secretory raug tso tawm los ntawm secretory vesicles. Nws tshwm sim thaum lub xov tooj ntawm tes tau txais lub teeb liab los ntawm sab nraud. Kev tso tawm ntawm cytokines, cov tshuaj hormones, neurotransmitters thiab lwm yam me me teeb liab molecules tshwm sim los ntawm kev tswj exocytosis. Yog li, qhov no yog cov ntsiab lus ntawm qhov sib txawv ntawm kev tsim thiab tswj exocytosis.
