Qhov txawv ntawm Lenalidomide thiab Thalidomide

Cov txheej txheem:

Qhov txawv ntawm Lenalidomide thiab Thalidomide
Qhov txawv ntawm Lenalidomide thiab Thalidomide

Video: Qhov txawv ntawm Lenalidomide thiab Thalidomide

Video: Qhov txawv ntawm Lenalidomide thiab Thalidomide
Video: Qhov Txawv Ntawm Lus Hmoob Thiab Lus Mab Mawb 2024, Hlis ntuj nqeg
Anonim

Qhov sib txawv tseem ceeb ntawm lenalidomide thiab thalidomide yog tias lenalidomide yog qhov sib piv ntau zog thiab tsawg dua thalidomide.

Ob leeg lenalidomide thiab thalidomide yog cov tshuaj muaj txiaj ntsig hauv kev kho mob qog noj ntshav. Ob qho tshuaj no yog siv rau cov neeg mob uas muaj ntau yam mob qog noj ntshav myeloma.

Lenalidomide yog dab tsi?

Lenalidomide yog cov tshuaj siv los kho mob qog noj ntshav xws li ntau yam myeloma thiab myelodysplastic syndrome. Feem ntau, cov tshuaj no yog siv nrog rau dexamethasone thiab nws yog siv los ntawm qhov ncauj ntawm cov tshuaj ntsiav. Lub npe lag luam tshaj plaws ntawm lenalidomide yog Revlimid. Cov tshuaj no tawm ntawm lub raum.

Qhov sib txawv ntawm Lenalidomide thiab Thalidomide
Qhov sib txawv ntawm Lenalidomide thiab Thalidomide

Daim duab 01: Cov qauv tshuaj ntawm Lenalidomide

Cov tshuaj formula ntawm lenalidomide yog C13H13N3O 3 Cov molar mass ntawm no compound yog 259.26 g / mol. Nws tshwm sim raws li kev sib xyaw ntawm haiv neeg vim tias qhov sib xyaw no yog chiral compound thiab muaj ob lub isomers uas tsis yog-superposable daim iav duab ntawm ib leeg.

Thaum xav txog kev siv tshuaj kho mob ntawm lenalidomide, nws yog siv los kho ntau yam myeloma (MM). Cov tshuaj no muaj zog dua piv rau thalidomide, lwm cov tshuaj siv los kho ntau yam myeloma. Tsis tas li ntawd, cov tshuaj no tseem ceeb hauv kev kho mob myelodysplastic syndrome, thiab mantle cell lymphoma.

Txawm li cas los xij, muaj qee qhov kev phiv tsis zoo ntawm cov tshuaj no thiab. Piv txwv li, raws plab, khaus khaus, mob pob qij txha, ua npaws, mob taub hau, thiab lwm yam tuaj yeem pom tias muaj kev cuam tshuam me me thaum thrombosis, pulmonary embolus, hepatotoxicity, thiab lwm yam.

Thalidomide yog dab tsi?

Thalidomide yog ib hom tshuaj siv los kho ntau yam myeloma, graft-vim-host kab mob, mob ruas, thiab lwm yam. Lub npe lag luam tshaj plaws ntawm cov tshuaj no yog Thalomid. Nws yog siv los ntawm qhov ncauj (los ntawm qhov ncauj) ua tshuaj ntsiav.

Qhov txawv tseem ceeb - Lenalidomide vs Thalidomide
Qhov txawv tseem ceeb - Lenalidomide vs Thalidomide

Daim duab 02: Cov Qauv Tshuaj ntawm Thalidomide

Cov tshuaj formula ntawm thalidomide yog C13H10N2O 4. Cov molar loj ntawm cov tshuaj no yog 258.22 g / mol. Nws tshwm sim nyob rau hauv daim ntawv ntawm ib tug racemic sib tov uas tsis yog-superposable daim iav dluab ntawm ib leeg.

Thaum xav txog kev siv tshuaj kho mob ntawm thalidomide, nws yog ib qho tseem ceeb hauv kev kho mob mob hnyav ntawm erythema nodosum leprosum, ntau yam myeloma (MM), kab mob graft-vsus-host, epidermolysis bullosa, thiab lwm yam.

Txawm li cas los xij, muaj qee qhov kev phiv ntawm cov tshuaj no thiab. Rau cov kev mob tshwm sim tshwm sim, qee qhov piv txwv suav nrog kev pw tsaug zog, ua pob khaus, thiab kiv taub hau. Tseem muaj qee qhov tsis zoo. e.g. ua rau yug tsis xws luag, ua kom ntshav txhaws ntau dhau, cuam tshuam rau cov hlab plawv, ua rau lub siab puas, thiab lwm yam.

Qhov txawv ntawm Lenalidomide thiab Thalidomide yog dab tsi?

Lenalidomide thiab thalidomide yog cov tshuaj siv rau kev kho mob qog noj ntshav xws li ntau yam myeloma. Lenalidomide yog cov tshuaj siv los kho cov qog nqaij hlav xws li ntau yam myeloma, thiab myelodysplastic syndrome. Thalidomide yog ib yam tshuaj siv los kho ntau yam myeloma, graft-vim-host kab mob, mob ruas, thiab lwm yam. Qhov sib txawv tseem ceeb ntawm lenalidomide thiab thalidomide yog tias lenalidomide yog qhov sib piv ntau zog thiab tsawg dua thalidomide.

Ntxiv mus, qee qhov kev mob tshwm sim ntawm lenalidomide suav nrog raws plab, khaus khaus, mob pob qij txha, ua npaws, mob taub hau, thiab lwm yam thaum qee qhov kev mob tshwm sim ntawm thalidomide muaj xws li pob khaus, tsaug zog, thiab kiv taub hau.

Hauv qab infographic qhia txog qhov sib txawv ntawm lenalidomide thiab thalidomide.

Qhov sib txawv ntawm Lenalidomide thiab Thalidomide hauv Tabular Form
Qhov sib txawv ntawm Lenalidomide thiab Thalidomide hauv Tabular Form

Summary – Lenalidomide vs Thalidomide

Lenalidomide thiab thalidomide yog cov tshuaj siv rau kev kho mob qog noj ntshav xws li ntau yam myeloma. Qhov sib txawv tseem ceeb ntawm lenalidomide thiab thalidomide yog tias lenalidomide yog qhov sib piv ntau zog thiab tsis muaj tshuaj lom ntau dua li thalidomide.

Pom zoo: