Qhov sib txawv tseem ceeb ntawm cholinergic thiab anticholinergic yog cov cholinergic cov neeg ua haujlwm ua raws li kev ua ntawm acetylcholine thaum cov tshuaj anticholinergic thaiv qhov kev ua ntawm acetylcholine.
Acetylcholine yog ib qho organic compound. Nws ua haujlwm raws li cov neurotransmitter hauv lub hlwb thiab lub cev ntawm ntau tus tsiaj thiab tib neeg. Nws yog ib qho tseem ceeb hauv kev xa cov lus tshuaj ntawm cov hlwb, neurons thiab lwm cov hlwb xws li cov leeg hlwb thiab cov qog hlwb. Ob leeg cholinergic thiab anticholinergic muaj feem xyuam rau acetylcholine. Cov no xa mus rau cov tshuaj uas muaj peev xwm tswj tau cov lus neurochemical hloov ntawm cov neurons thiab hlwb.
Cholinergic yog dab tsi?
Cov tshuaj cholinergic yog cov tshuaj sib txuas uas tuaj yeem ua rau muaj kev ua haujlwm ntawm acetylcholine. Cov neeg ua haujlwm no tuaj yeem ua raws li kev ua haujlwm ntawm butyrylcholine ib yam nkaus. "choline" yog ib feem ntawm cov neurotransmitter acetylcholine. Lub paj hlwb parasympathetic tau hais tias yog cholinergic nkaus vim nws siv acetylcholine yuav luag tsuas yog xa cov lus ntawm cov hlwb thiab lub hom phiaj. Tsis tas li ntawd, neuromuscular junctions thiab preganglionic neurons ntawm lub paj hlwb sympathetic yog cholinergic. Cov receptors ntawm merocrine hws qog kuj yog cholinergic.
Daim duab 01: Ib qho Tshuaj Cholinergic
Ib yam khoom lossis ib qho ligand uas tuaj yeem tsim, hloov lossis tso tawm acetylcholine lossis butyrylcholine kuj muaj npe ua cov tshuaj cholinergic. Tsis tas li ntawd, yog tias tus neeg txais kev pab lossis ib lub synapse siv acetylcholine ua cov tshuaj neurotransmitter, lawv kuj muaj npe hu ua cholinergic agents.
YAnticholinergic yog dab tsi?
Anticholinergic cov tshuaj yog cov tshuaj uas tuaj yeem thaiv qhov kev ua ntawm acetylcholine. Qhov kev thaiv no feem ntau tshwm sim ntawm lub synapse hauv nruab nrab thiab peripheral paj hlwb. Cov neeg ua haujlwm no tuaj yeem xaiv qhov kev sib txuas ntawm acetylcholine nrog cov receptors hauv cov hlab ntsha ntawm lub paj hlwb peripheral. Muaj peb hom tshuaj anticholinergic:
- Antimuscarinic blockers
- Ganglionic blockers
- Neuromuscular Blockers
Daim duab 02: Cov Qauv Tshuaj ntawm Acetylcholine
tshuaj Anticholinergic tseem ceeb heev hauv cov tshuaj kho ntau yam kab mob xws li kiv taub hau, cov tsos mob extrapyramidal, kab mob plab, insomnia, ua pa nyuaj, thiab lwm yam. Txawm li cas los xij, muaj kev phiv ntawm kev siv cov tshuaj no thiab.
- kev sib koom siab tsis zoo
- Dementia
- Kev txo qis qis hauv qhov ntswg thiab caj pas
- qhov ncauj qhuav nrog nce kab mob hniav
- nce lub cev kub, thiab lwm yam.
Qhov txawv ntawm Cholinergic thiab Anticholinergic yog dab tsi?
Qhov sib txawv tseem ceeb ntawm cholinergic thiab anticholinergic yog cov cholinergic cov neeg ua haujlwm ua raws li qhov kev txiav txim ntawm acetylcholine, thaum cov tshuaj anticholinergic thaiv qhov kev txiav txim ntawm acetylcholine. Tsis tas li ntawd, cholinergic cov neeg ua haujlwm tuaj yeem ua rau parasympathetic thiab sympathetic paj hlwb, thaum cov tshuaj anticholinergic feem ntau ua rau hauv nruab nrab thiab peripheral paj hlwb. Dhau li, piv txwv ntawm cov tshuaj cholinergic muaj xws li pilocarpine, physostigmine, thiab lwm yam. Meanwhile, piv txwv ntawm cov tshuaj anticholinergic muaj xws li atropine, clidinium, Cogentin, thiab lwm yam.
Cov lus qhia hauv qab no qhia txog qhov sib txawv ntawm cholinergic thiab anticholinergic hauv daim ntawv tabular.
Summary – Cholinergic vs Anticholinergic
Cov ntsiab lus cholinergic thiab anticholinergic yog hais txog cov tshuaj siv tshuaj uas tuaj yeem tswj cov tshuaj neurochemical hloov ntawm cov neurons thiab hlwb. Qhov sib txawv tseem ceeb ntawm cholinergic thiab anticholinergic yog cov cholinergic cov neeg ua haujlwm zoo li kev ua ntawm acetylcholine thaum cov tshuaj anticholinergic thaiv qhov kev ua ntawm acetylcholine. Cov tshuaj cholinergic tuaj yeem ua rau cov kab mob parasympathetic thiab sympathetic paj hlwb thaum cov tshuaj anticholinergic ua feem ntau ntawm lub hauv nruab nrab thiab lub paj hlwb peripheral.
