Qhov sib txawv tseem ceeb ntawm transaldolase thiab transketolase yog lawv txoj haujlwm. Transaldolase catalyzes hloov dua siab tshiab ntawm sedoheptulose 7-phosphate thiab glyceraldehydes 3-phosphate mus rau hauv erythrose 4-phosphate thiab fructose 6-phosphate, thaum transketolase catalyzes hloov dua siab tshiab ntawm xylulose 5-phosphate thiab ribose rau hauv 5-phoste-phosphate thiab ribose phosphate..
Txoj hauv kev pentose-phosphate yog txoj hauv kev metabolic uas tshwm sim thaum uas tig mus rau glycolysis. Nws muaj ob txoj kev sib txawv. Nyob rau hauv txoj kev pentose phosphate, NADPH yog tsim nyob rau hauv oxidative theem, thaum pentose qab zib yog tsim nyob rau hauv lub non-oxidative theem. Ntxiv rau pentoses thiab NADPH, txoj hauv kev no tsim cov ribose 5-phosphate, uas yog ib qho precursor rau nucleotide synthesis. Transaldolase thiab transketolase yog ob lub enzymes koom nrog hauv theem tsis-oxidative ntawm pentose phosphate txoj kev.
Dab tsi yog Transaldolase?
Transaldolase yog ib qho enzyme catalyzing hloov pauv ntawm sedoheptulose-7-phosphate thiab glyceraldehyde-3-phosphate rau hauv erythrose-4-phosphate thiab fructose-6-phosphate. Yog li ntawd, nws koom nyob rau hauv lub non-oxidative theem ntawm pentose phosphate txoj kev. Transaldolase, ua ke nrog transketolase, txuas cov pentose phosphate txoj kev thiab glycolysis nrog ib leeg.
Daim duab 01: Transaldolase
Structurally, nws yog ib qho enzyme txog 34kDa, thiab nws muaj ib qho ntawm 337 amino acids. Nws pom yuav luag txhua qhov chaw hauv archaea, kab mob thiab eukarya. Cov noob TALDO1 cov lej rau cov enzyme no hauv tib neeg.
Transketolase yog dab tsi?
Transketolase yog lwm cov enzyme koom nrog hauv cov theem tsis-oxidative ntawm pentose phosphate txoj kev. Cov enzyme no muaj nyob rau hauv ntau yam kab mob, nrog rau cov kab mob, nroj tsuag, thiab tsiaj txhu. Nws catalyzes hloov dua siab tshiab ntawm xylulose 5-phosphate thiab ribose 5-phosphate rau glyceraldehyde 3-phosphate thiab sedoheptulose 7-phosphate.
Daim duab 02: Transketolase
Ntxiv mus, nws catalyzes hloov pauv ntawm xylulose 5-phosphate thiab erythrose 4-phosphate rau glyceraldehyde 3-phosphate thiab fructose 6-phosphate. Cov gene TKT codes rau cov enzyme transketolase. Zoo ib yam li transaldolase, transketolase txhawb kev sib txuas ntawm glycolysis thiab pentose phosphate txoj kev.
Dab tsi yog qhov zoo sib xws ntawm Transaldolase thiab Transketolase?
- Ob leeg transaldolase thiab transketolase yog cov enzymes koom nrog hauv txoj kev pentose phosphate.
- Lawv catalyze cov tshuaj tiv thaiv ntawm cov tsis-oxidative theem ntawm PPT.
- Transaldolase thiab transketolase txuas glycolysis thiab pentose phosphate txoj hauv kev.
Qhov txawv ntawm Transaldolase thiab Transketolase yog dab tsi?
Transaldolase yog ib qho enzyme catalyzing hloov pauv ntawm sedoheptulose 7-phosphate thiab glyceraldehydes 3-phosphate rau erythrose 4-phosphate thiab fructose 6-phosphate, thaum transketolase yog lwm enzyme catalyzing lub xylulose 5-phosphate thiab phosphate. Sedoheptulose 7-phosphate thiab glyceraldehyde 3-phosphate. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm transaldolase thiab transketolase. Dhau li ntawd, TALDO1 noob codes rau transaldolase thaum TKT noob codes rau transketolase.
Ntxiv mus, transaldolase hloov pauv peb-carbon chav tsev, thaum transketolase hloov ob chav tsev carbon. Yog li, peb tuaj yeem xav txog qhov no yog lwm qhov sib txawv ntawm transaldolase thiab transketolase. Tsis tas li ntawd, transaldolase yog ib qho pyridoxal phosphate (PLP)-nyob enzyme, thaum transketolase yog thiamine pyrophosphate (vitamin B1)-nyob enzyme.
Hauv qab infographic tabulates qhov sib txawv ntawm transaldolase thiab transketolase.
Summary – Transaldolase vs Transketolase
Transaldolase thiab transketolase yog ob lub enzymes koom nrog hauv cov theem uas tsis yog oxidative ntawm pentose phosphate txoj kev. Cov enzymes txuas glycolysis thiab pentose phosphate txoj kev. Transaldolase catalyzes kev hloov pauv ntawm sedoheptulose 7-phosphate thiab glyceraldehydes 3-phosphate rau erythrose 4-phosphate thiab fructose 6-phosphate. Lub caij no, transketolase catalyzes kev hloov pauv ntawm xylulose 5-phosphate thiab ribose 5-phosphate rau hauv sedoheptulose 7-phosphate thiab glyceraldehyde 3-phosphate. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm transaldolase thiab transketolase.
