Qhov sib txawv tseem ceeb ntawm epimerization thiab racemization yog tias epimerization cuam tshuam nrog kev hloov pauv ntawm ib qho epimer rau hauv nws cov chiral counterpart whereas racemization yog hloov dua siab tshiab ntawm ib hom kab mob optically mus rau hauv hom optically inactive.
Epimerization thiab racemization yog tshuaj hloov pauv. Lawv sib txawv ntawm txhua lwm yam nrog rau cov txheej txheem, cov khoom kawg, cov kev mob tshwm sim, thiab lwm yam. Cov khoom kawg ntawm cov txheej txheem epimerization yog chiral counterpart ntawm epimer thaum cov khoom kawg ntawm racemization yog ib hom tshuaj optically inactive. Peb hu qhov no optically inactive hom "racemate" los yog "racemic sib tov".
Epimerization yog dab tsi?
Epimerization yog cov tshuaj hloov pauv tshuaj uas suav nrog kev hloov pauv ntawm epimer rau hauv nws cov chiral counterparts. Feem ntau, hom kev tshwm sim no tshwm sim thaum lub sij hawm condensed tannins depolymerization tshwm sim. Feem ntau, cov tshuaj tiv thaiv epimerization yog cov tshuaj tiv thaiv tus kheej thiab cov txheej txheem qeeb. Yog li, nws tuaj yeem ua rau cov enzymes. Piv txwv li, kev hloov pauv ntawm N-acetylglucosamine rau hauv N-acetylmannosamine yog cov tshuaj tiv thaiv epimerization uas tshwm sim nyob rau hauv lub xub ntiag ntawm renin-binding protein. Ntawm no, qhov no renin-binding protein ua raws li catalyst rau cov tshuaj tiv thaiv.
Kev Sib Tw yog dab tsi?
Racemization yog cov tshuaj hloov pauv tshuaj uas cuam tshuam nrog kev hloov pauv ntawm hom kab mob optically mus rau hom kab mob optically. Qhov no txhais tau hais tias cov tshuaj tiv thaiv no tuaj yeem hloov ib nrab ntawm cov molecules ntawm cov khoom sib xyaw uas muaj cov kab mob optically ua rau lawv daim iav duab enantiomers. Qhov no yog vim hais tias, tom qab qhov kev hloov dua siab tshiab no, qhov sib xyaw no muaj cov lej sib npaug ntawm cov molecules nrog kev sib hloov kho qhov muag thiab ua rau qhov tsis muaj zog. Peb hu cov txheej txheem no racemization vim tias qhov sib tov uas muaj qhov sib npaug ntawm qhov sib npaug ntawm qhov kev sib hloov kho qhov muag yog hu ua racemic sib xyaw lossis racemate.
Daim duab 01: Ib qho kev sib xyaw ntawm Racemic muaj qhov sib xyaw ntawm Enantiomers nrog Kev Sib Hloov Kho qhov muag
Dhau li ntawm, qhov kev hloov pauv no ua rau muaj qhov sib txawv ntawm cov tshuaj thiab lub cev ntawm cov tshuaj lom neeg thawj zaug thiab cov khoom sib xyaw. Racemization hloov qhov ntom ntom, melting point, kub ntawm fusion, solubility, refractive index, thiab lwm yam. Thaum xav txog cov txheej txheem racemization, peb tuaj yeem tau txais cov khoom sib xyaw racemic yooj yim los ntawm kev sib xyaw kom muaj nuj nqis ntawm cov ntshiab enantiomers. Ntxiv mus, nws tshwm sim nyob rau hauv chemical interconversion txheej txheem. Tsis tas li ntawd, racemization yuav tshwm sim thaum lub sij hawm unimolecular hloov cov tshuaj tiv thaiv, unimolecular tshem tawm cov tshuaj tiv thaiv, unimolecular aliphatic electrophilic hloov tshuaj, dawb radical hloov tshuaj, thiab lwm yam.
Qhov txawv ntawm Epimerization thiab Racemization yog dab tsi?
Epimerization thiab racemization yog tshuaj hloov pauv. Lawv sib txawv ntawm ib leeg nyob rau hauv ntau txoj kev nrog rau cov txheej txheem, cov khoom kawg, cov tshuaj tiv thaiv tej yam kev mob, thiab lwm yam. Qhov tseem ceeb sib txawv ntawm epimerization thiab racemization yog hais tias epimerization yuav hloov dua siab tshiab ntawm ib tug epimer rau nws chiral counterpart whereas racemization yog ib tug hloov dua siab tshiab ntawm ib tug optically active. hom nyob rau hauv ib hom kab mob optically inactive. Ntxiv mus, nyob rau hauv epimerization, cov khoom kawg yog ib tug chiral counterpart ntawm lub epimer whereas, nyob rau hauv racemization, cov khoom kawg yog ib tug optically inactive tshuaj hom, piv txwv li ib haiv neeg sib tov los yog racemate.
Dhau li, qhov sib txawv ntxiv ntawm epimerization thiab racemization yog tias feem ntau, epimerization yog ib qho txheej txheem spontaneous thiab cov txheej txheem qeeb uas tuaj yeem nrawm siv cov catalysts. Txawm li cas los xij, racemization yog cov txheej txheem uas tsis yog tshwm sim, yog li peb yuav tsum ua kom nws tshwm sim los ntawm kev siv tshuaj. Peb tuaj yeem ua tau yooj yim los ntawm kev sib tov sib npaug ntawm cov ntshiab enantiomers.
Summary – Epimerization vs Racemization
Epimerization thiab racemization yog tshuaj hloov pauv. Lawv sib txawv ntawm ib leeg nyob rau hauv ntau txoj kev nrog rau cov txheej txheem, cov khoom kawg, cov tshuaj tiv thaiv tej yam kev mob, thiab lwm yam. Qhov tseem ceeb sib txawv ntawm epimerization thiab racemization yog hais tias epimerization yuav hloov dua siab tshiab ntawm ib tug epimer rau nws chiral counterpart whereas racemization yog ib tug hloov dua siab tshiab ntawm ib tug optically active. hom rau hauv hom kab mob optically tsis ua haujlwm.
