Qhov sib txawv tseem ceeb ntawm phagocytosis thiab opsonization yog tias phagocytosis yog ib qho kev ua haujlwm los ntawm qee lub hlwb lossis cov kab mob kom noj lossis nqus cov khoom txawv teb chaws thaum opsonization yog cov txheej txheem uas cov kab mob raug tshem tawm ntawm lub cev thaum raug cim los ntawm opsonins..
Immunologic cov lus teb tuaj yeem ua tau los yog hloov tau. Cov kab mob muaj cov kab mob paub txog receptors uas ua rau nws yooj yim dua los txheeb xyuas tus tswv tsev. Opsonization thiab phagocytosis yog ob qho kev tiv thaiv kab mob. Nyob rau hauv opsonization, tus tswv tsev txheeb xyuas thiab cim invading hais rau kev puas tsuaj los ntawm zus tau tej cov opsonins. Phagocytosis yog ib txoj hauv kev uas qee lub cev tiv thaiv kab mob nkag mus thiab rhuav tshem cov khoom nkag lossis cov khoom txawv teb chaws los ntawm lub cev.
Phagocytosis yog dab tsi?
Phagocytosis yog ib qho kev tiv thaiv kev tua los ntawm qee lub hlwb lossis cov kab mob kom tshem tawm cov khoom txawv teb chaws ntawm lub cev. Lawv ingest los yog engulf txawv teb chaws hais thiab rhuav tshem lawv. Phagocytes yog cov hlwb uas ua rau phagocytosis. Phagocytes yog hom qe ntshav dawb, tshwj xeeb tshaj yog, neutrophils, monocytes thiab macrophages muaj nyob hauv cov ntshav. Cov hlwb no tiv thaiv lub cev los ntawm kev txheeb xyuas cov khoom txawv teb chaws xws li cov kab mob, co toxins, tuag thiab tuag somatic hlwb. Tom qab ntawd phagocytes engulf thiab rhuav tshem lawv. Qhov tseeb, phagocytes yog ib feem ntawm lub cev tiv thaiv kab mob. Lawv raug tsim nyob rau hauv cov pob txha pob txha los ntawm mitotic cell division.
Daim duab 01: Phagocytosis
Phagocytosis yog ib hom kab mob endocytosis. Los ntawm phagocytosis, cov khoom uas muaj nyob rau hauv cov qauv hu ua phagosome. Thaum lawv raug daig hauv phagosome, lawv fuse nrog ib tug lysosome thiab tsim phagolysosome. Tom qab ntawd siv cov lysosome hydrolase enzymes, cov khoom hauv phagosome yog degraded thiab puas.
Phagocytosis yog txheej txheem tseem ceeb heev hauv kev pov tseg cov hlwb somatic uas tau ua tiav cov txheej txheem cell tuag. Cov hlwb no yuav tsum tau muab pov tseg los ntawm lub cev los muab qhov chaw rau cov hlwb tshiab. Yog li ntawd, nws yog tsuas yog ua los ntawm phagocytes nyob rau hauv lub cev. Cov hlwb tuag lossis tuag tso tawm qee yam tshuaj uas tuaj yeem kuaj pom los ntawm cov phagocytes uas tsis yog neeg ua haujlwm thiab noj los ntawm phagocytosis. Lub caij no, cov kws tshaj lij phagocytes ntes cov kab mob thiab lwm yam kab mob ntawm lub cev los ntawm phagocytosis. Cov kab mob tsis tuaj yeem raug rhuav tshem los ntawm phagocytosis vim lawv siv tib lub tswv yim ntawm phagocytosis txhawm rau txhawm rau cov qe ntshav dawb thiab kis mus rau cov tswv tsev.
Opsonization yog dab tsi?
Opsonization yog txheej txheem uas tshem tawm cov kab mob ntawm lub cev thaum raug cim los ntawm opsonins. Opsonins yog cov molecules uas tuaj yeem paub cov kab mob. Cov kab mob muaj cov kab mob paub txog receptors. Opsonins muaj nyob rau hauv phagocytes thiab pab kom paub txog cov kab mob kev paub txog receptors. Qee qhov piv txwv ntawm opsonins yog receptors xws li Fc receptor thiab ntxiv receptor 1 (CR1). Opsonins kuj muaj lub peev xwm los txhawb txoj hauv kev ntxiv thiab ua kom phagocytosis.
Daim duab 02: Opsonization
Opsonins khi rau lub epitope ntawm tus kab mob. Thaum opsonins khi rau cov kab mob, phagocytes tau nyiam rau cov kab mob thiab pab txhawb phagocytosis. Opsonization tseem tuaj yeem qhib cov lus teb tiv thaiv kab mob. Ntawm no, cov tshuaj tiv thaiv IgG khi rau cov kab mob opsonized. Yog li, qhov no tso cai rau cov tshuaj tiv thaiv kab mob ntawm cov cell-mediated cytotoxicity hauv cov hlwb. Thaum tsis muaj opsonins, qhov mob tuaj yeem tshwm sim thiab ua rau cov ntaub so ntswg noj qab haus huv thaum kis mob.
Dab tsi zoo sib xws ntawm Phagocytosis thiab Opsonization?
- Phagocytosis thiab opsonization yog lub cev tiv thaiv kab mob.
- Cov khoom txawv teb chaws lossis cov kab mob nkag mus tau raug txheeb xyuas thiab tsom los ntawm opsonization rau kev puas tsuaj los ntawm phagocytosis.
- Ob txheej txheem tseem ceeb heev los tiv thaiv peb ntawm kev kis kab mob thiab kab mob.
Qhov txawv ntawm Phagocytosis thiab Opsonization yog dab tsi?
Phagocytosis yog cov txheej txheem los ntawm qee lub hlwb tshem tawm cov khoom txawv teb chaws los ntawm kev engulfing lawv thiab rhuav tshem. Ntawm qhov tod tes, opsonization yog cov txheej txheem uas cov kab mob raug tshem tawm ntawm lub cev thaum raug cim los ntawm opsonins. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm phagocytosis thiab opsonization. Tsis tas li ntawd, cov hlwb koom nrog hauv phagocytosis yog phagocytes thaum molecules koom nrog hauv opsonization yog opsonins.
Hauv qab infographic qhia txog qhov sib txawv ntawm phagocytosis thiab opsonization.
Summary – Phagocytosis vs Opsonization
Phagocytosis yog ib qho cuab yeej siv los ntawm lub cev tiv thaiv kab mob thiab qee yam kab mob txhawm rau txhawm rau kis kab mob thiab rhuav tshem lawv. Phagocytes ua rau phagocytosis. Nws yog hom kab mob endocytosis uas ua rau cov khoom siv hauv cov qauv hu ua phagosome. Meanwhile, opsonization yog lub tshuab uas invading hais yog tsom rau kev puas tsuaj los ntawm phagocytosis. Opsonin molecules ua opsonization. Qhov no qhia txog qhov sib txawv ntawm phagocytosis thiab opsonization.
