Qhov Tseem Ceeb Qhov txawv - Intrinsic vs Extrinsic Proteins
Cells yog ib puag ncig los ntawm cell membranes, uas yog tsim los ntawm lipid bilayer, proteins, thiab carbohydrates. Proteins yog embedded nyob rau hauv lub lipid bilayer ntawm lub cell membrane. Cells tas li thauj ions thiab lwm yam tsim nyog molecules nyob rau hauv thiab tawm lub hlwb los ntawm cov proteins. Qee cov proteins txuas mus los ntawm ob txheej thaum qee cov protein txuas los ntawm ib sab ntawm daim nyias nyias. Cov proteins cuam tshuam nrog cov cell membrane hu ua membrane proteins. Muaj ob lub membrane proteins hu ua intrinsic thiab extrinsic proteins. Intrinsic proteins yog cov transmembrane proteins uas yog embedded nyob rau hauv lub lipid bilayer. Lawv nthuav tawm ntawm ib sab mus rau lwm sab. Extrinsic proteins yog cov membrane proteins uas nyob sab nraum daim nyias nyias thiab khi tsis muaj zog rau daim nyias nyias. Qhov no yog qhov sib txawv tseem ceeb ntawm cov khoom siv sab hauv thiab sab nrauv.
Dab tsi yog Cov Proteins?
Intrinsic proteins yog ib hom membrane proteins uas tseem ceeb hauv kev thauj ions los yog molecules hla lub cell membrane. Intrinsic proteins yog embedded nyob rau hauv daim nyias nyias. Qee cov proteins intrinsic hla tag nrho los ntawm daim nyias nyias mus rau ob sab ntawm daim nyias nyias, thaum qee cov proteins hauv lub cev tsuas yog ib feem ntawm cov ntaub so ntswg. Intrinsic proteins uas txuas ntawm ib sab ntawm daim nyias nyias mus rau lwm sab yog hu ua transmembrane proteins. Transmembrane proteins ua haujlwm raws li cov proteins channel kom txav cov molecules thiab ions hla cov membrane hauv thiab tawm ntawm tes. Cov proteins no muaj qhov pores hauv lawv cov qauv.
Daim duab 01: Intrinsic Proteins
Intrinsic proteins muaj ib lossis ntau qhov embedded los ntawm phospholipid bilayer. Intrinsic proteins yog ntau hydrophobic thiab tsawg hydrophilic. Hydrophobic sab chains yog ib qho tseem ceeb hauv kev thauj cov roj acyl pawg ntawm lipid bilayer. Feem ntau ntawm cov membrane spanning domains yog alpha helices los yog beta strands.
Dab tsi yog Extrinsic Proteins?
Extrinsic proteins yog ib hom membrane proteins uas yog xoob khi rau daim nyias nyias los ntawm sab nraud. Lawv raug khi nrog kev sib cuam tshuam ntawm cov molecular tsis muaj zog xws li ionic, hydrogen thiab / lossis Van der Waals bonds. Extrinsic proteins tseem hu ua peripheral proteins. Cov proteins no yog hydrophilic hauv qhov xwm txheej. Lawv cuam tshuam nrog cov proteins ib txwm lossis nrog lub taub hau ntawm cov lipid molecules. Peripheral proteins ntawm lub extracellular membrane ua hauj lwm raws li receptors nyob rau hauv lub cell mus rau lub cell signaling los yog kev sib cuam tshuam. Peripheral proteins uas nyob rau hauv lub ntsej muag cytosolic ua hauj lwm raws li cytoskeletal proteins xws li spectrin, actin, protein kinase C, thiab lwm yam. Qee cov peripheral proteins koom nrog hauv cov teeb liab transduction.
Daim duab 02: Extrinsic Proteins
Dab tsi yog qhov zoo sib xws ntawm Intrinsic thiab Extrinsic Proteins?
Intrinsic thiab extrinsic proteins yog membrane proteins
Qhov txawv ntawm Intrinsic thiab Extrinsic Proteins yog dab tsi?
Intrinsic vs Extrinsic Proteins |
|
| Intrinsic proteins yog cov membrane proteins uas yog embedded kiag li los yog ib feem los ntawm cov lipid bilayer ntawm daim nyias nyias. | Extrinsic proteins yog cov proteins uas xoob khi uas nyob sab nraum daim nyias nyias. |
| Intrinsic Proteins tseem hu ua cov proteins ib txwm lossis cov proteins sab hauv. | Extrinsic Proteins tseem hu ua peripheral proteins lossis lwm cov proteins. |
| Intrinsic proteins yog embedded kiag li los yog ib feem ntawm daim nyias nyias. Qee lub sij hawm lawv hla daim nyias nyias ob peb zaug. | Extrinsic proteins yog khi rau cell membrane los ntawm sab nraud. |
| Intrinsic proteins suav txog kwv yees li 70% ntawm cov protein membrane. | Extrinsic proteins account rau kwv yees li 30% ntawm cov proteins membrane. |
| Hydrophilic thiab Hydrophobic Nature | |
| Intrinsic Proteins yog ntau hydrophobic thiab tsawg hydrophilic. | Extrinsic Proteins yog ntau hydrophilic thiab tsawg hydrophobic. |
| Kev tshem tawm ntawm Membrane | |
| Intrinsic proteins tsis tau yooj yim tshem tawm ntawm daim nyias nyias. | Extrinsic proteins tau yooj yim tshem tawm ntawm daim nyias nyias. |
| Kev ua haujlwm hauv Membrane | |
| Intrinsic proteins ua raws li cov neeg nqa khoom noj proteins, enzymes, permeases, thauj channel, thiab lwm yam. | Extrinsic proteins ua raws li receptors, antigens, chaw lees paub, thiab lwm yam. |
| Cov Nyiaj Txhaum Cai Nrog Cell Membrane | |
| Intrinsic Proteins yog embedded nyob rau hauv lub lipid bilayer, tsim muaj zog sib cuam tshuam. | Extrinsic Proteins yog xoob khi rau daim nyias nyias los ntawm kev sib cuam tshuam tsis muaj molecular. |
| Examples | |
| Glycophorin, rhodopsin, NADH dehydrogenase, thiab lwm yam. | Cytochrome C, erythrocyte spectrin, thiab lwm yam. |
Summary – Intrinsic vs Extrinsic Proteins
Membrane proteins tau muab faib ua ob pawg hu ua intrinsic thiab extrinsic proteins raws li qhov kev cuam tshuam ntawm cov proteins thiab daim nyias nyias. Intrinsic membrane proteins yog embedded nyob rau hauv daim nyias nyias. Lawv txuas mus tas li rau daim nyias nyias. Extrinsic proteins txuas rau daim nyias nyias los ntawm sab nraud. Lawv tau tuav los ntawm cov khoom tsis muaj zog molecular xws li ionic, hydrogen, lossis Van der Waals bonds. Qhov no yog qhov sib txawv ntawm cov khoom siv sab hauv thiab sab nrauv.
Download PDF Version of Intrinsic vs Extrinsic Proteins
Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline hom phiaj raws li cov ntawv sau tseg. Thov download PDF version ntawm no Qhov txawv nruab nrab ntawm Intrinsic thiab Extrinsic Proteins.
