Qhov Tseem Ceeb - Seminoma vs Nonseminoma
Cov qog qog nqaij hlav tuaj yeem muab faib ua pawg sib txawv raws li lawv cov yam ntxwv morphological. Seminomas thiab nonseminomas yog arguably ob feem ntau ntsib ntau yam ntawm neoplastic lesions nyob rau hauv cov txiv neej gonads. Seminomatous qog yog cov kab mob qog nqaij hlav uas tsim los ntawm cov hlwb uas zoo li cov kab mob primordial los yog gonocytes thaum ntxov thiab cov qog tsis yog cov qog muaj cov kab mob uas tsis txawv txav uas tuaj yeem sib txawv ntawm cov kab sib txawv. Raws li, seminomas muaj cov hlwb sib txawv, tsis zoo li cov nonseminomas uas muaj cov hlwb tsis sib xws uas muaj peev xwm sib txawv raws li cov kab mob ntawm tes. Qhov no tuaj yeem suav tias yog qhov sib txawv tseem ceeb ntawm cov qog no.
Seminoma yog dab tsi?
Cov qog nqaij hlav seminomatous yog cov kab mob qog nqaij hlav ntawm cov hlwb uas zoo li cov kab mob primordial los yog gonocytes thaum ntxov. Cov no yog hom kab mob qog noj ntshav uas muaj ntau tshaj plaws nyob rau hauv lub xyoo caum thib peb ntawm lub neej.
Cov qog no tshwm sim los ntawm cov kab mob ua ntej hu ua intratubular germ cell neoplasia (ITGCN). Qhov mob no tshwm sim hauv utero thiab nce mus rau hauv cov qog tom qab kev laus. Kev soj ntsuam microscopic ntawm ITGCN qhia pom muaj cov hlwb uas muaj ob npaug ntawm qhov loj ntawm cov kab mob ib txwm muaj nrog cov nucleus loj thiab cov cytoplasm ntshiab.
Muaj ob lub ntsiab morphological ntau yam ntawm cov qog seminomatous li,
- Seminomas
- Spermatocytic seminomas
Seminomas
Cov no yog hom kab mob qog nqaij hlav ntau tshaj plaws uas muaj qhov tshwm sim siab tshaj plaws nyob rau xyoo thib peb ntawm lub neej. Ib qho qog zoo sib xws hu ua dysgerminoma tshwm sim hauv zes qe menyuam. Seminomas muaj 12p isochromosome thiab nthuav qhia NANOG thiab OCT3/4. Feem coob ntawm cov qog no muaj qhov hloov pauv ntawm KIT thiab.
Morphologically ib tug classic seminoma yog cov qog loj uas yog puag ncig lossis polyhedral hauv cov duab. Nws muaj ib tug zoo-tsim cell membrane nrog ib tug ntshiab los yog dej cytoplasm. Feem ntau ntawm cov cell muaj ib tug loj central nucleus nrog ib tug tseem ceeb nucleus. Kwv yees li 15% ntawm seminomas muaj syncytiotrophoblasts nyob rau hauv rooj plaub uas cov ntshav hCG nce siab.
YSpermatocytic Seminoma
Cov kab mob seminomatous no feem ntau cuam tshuam rau cov txiv neej laus dua 65 xyoo. Nyob rau hauv sib piv rau classic seminomas, Spermatocytic seminomas yog qeeb zuj zus neoplastic lesions, thiab qhov tshwm sim yog tsis tshua muaj heev. Vim tias qhov qeeb ntawm kev loj hlob ntawm cov qog no, lawv muaj qhov zoo heev.
Daim duab 01: Histological tshwm sim ntawm Seminoma
Spermatocytic seminomas yog tsim los ntawm cov hlwb nruab nrab nrog eosinophilic cytoplasm.
Nonseminoma yog dab tsi?
Nonseminomatous qog muaj cov embryonic qia hlwb tsis txawv uas tuaj yeem sib txawv ntawm cov kab sib txawv.
Subcategories ntawm nonseminomatous qog yog,
- Embryonal carcinoma
- Yawg sac tumor
- Choriocarcinoma
Embryonal Carcinoma
Cov qog no feem ntau tshwm sim hauv pawg hnub nyoog 20-30 thiab muaj kev txhoj puab heev dua li cov seminomas. Embryonal carcinomas muaj ib tug tubular los yog alveolar hom ntawm histological kev npaj.
Yolk Sac Tumors
Nov yog cov qog qog hlav qog uas tshwm sim hauv cov menyuam mos thiab menyuam yaus hnub nyoog qis dua 3 xyoos. Txawm hais tias muaj qhov tshwm sim zoo heev hauv cov hnub nyoog saum toj no, cov qog nqaij hlav hauv cov neeg laus tuaj yeem ua rau muaj kev hem thawj rau lub neej. Histologically cov qog no yog nonencapsulated thiab muaj ib tug mucinous tsos. Cov qauv papillary kuj tseem tsis tshua pom nyob hauv lawv.
Daim duab 02: Hla-Section ntawm Testicle
Choriocarcinoma
Choriocarcinomas yog qhov tsawg kawg nkaus tab sis cov qog nqaij hlav hnyav heev uas suav nrog tsawg dua 1% ntawm tag nrho cov qog qog ntshav. Lawv tsis ua rau muaj qhov loj ntawm cov noob qes thiab yuav nthuav tawm raws li lub palpable nodule. Muaj ob hom cell hauv cov qog ua syncytiotrophoblasts thiab cytotrophoblasts.
Dab tsi yog qhov zoo sib xws ntawm Seminoma thiab Nonseminoma?
Ob leeg yog ntau hom qog nqaij hlav
Qhov txawv ntawm Seminoma thiab Nonseminoma yog dab tsi?
Seminoma vs Nonseminoma |
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| Cov qog nqaij hlav seminomatous yog cov kab mob qog nqaij hlav ntawm cov hlwb uas zoo li cov kab mob primordial lossis gonocytes thaum ntxov. | Nonseminomatous qog muaj cov embryonic qia hlwb tsis txawv uas tuaj yeem sib txawv ntawm cov kab sib txawv. |
Summary – Seminoma vs Nonseminoma
Seminomatous qog yog cov kab mob qog nqaij hlav uas tsim los ntawm cov hlwb uas zoo li cov kab mob primordial lossis gonocytes thaum ntxov thaum cov qog nonseminomatous yog cov pawg uas tsis muaj qhov sib txawv ntawm cov embryonic qia hlwb uas tuaj yeem sib txawv ntawm cov kab sib txawv. Seminomas muaj cov hlwb sib txawv, tab sis cov nonseminomas muaj cov hlwb tsis txawv. Qhov no tuaj yeem raug coj los ua qhov sib txawv tseem ceeb ntawm cov qog no.
Download the PDF Version of Seminoma vs Nonseminoma
Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline hom phiaj raws li daim ntawv ceeb toom. Thov download PDF version ntawm no Qhov txawv Ntawm Seminoma thiab Nonseminoma
