Qhov txawv ntawm T Pab thiab T Cytotoxic Cells

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Qhov txawv ntawm T Pab thiab T Cytotoxic Cells
Qhov txawv ntawm T Pab thiab T Cytotoxic Cells

Video: Qhov txawv ntawm T Pab thiab T Cytotoxic Cells

Video: Qhov txawv ntawm T Pab thiab T Cytotoxic Cells
Video: Qhov Sib Txawv Ntawm Khetos Qhov Kev Ua Neej thiab Cov Tib Neeg Qias Vuab Tsuab Qhov Kev Ua Neeg 2024, Kaum ib hlis
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Qhov Tseem Ceeb Qhov txawv - T Pab vs T Cytotoxic Cells

Lymphocytes yog ib hom qe ntshav dawb uas muaj tib lub hauv paus nucleus. Lawv yog cov tseem ceeb tiv thaiv hlwb nyob rau hauv vertebrates tiv thaiv kab mob. T hlwb los yog T lymphocytes yog ib tug subtype ntawm lymphocytes. Lawv yog ib feem ntawm kev tiv thaiv kab mob thiab feem ntau koom nrog hauv cell mediated tiv thaiv kab mob uas tsis tshwm sim los ntawm kev tsim cov tshuaj tiv thaiv kab mob. T hlwb yog tsim los ntawm cov pob txha pob txha. Tom qab ntawd lawv mus rau thymus thiab ua kom loj hlob. Cov T hlwb no tuaj yeem txawv ntawm lwm cov lymphocytes vim muaj T cell receptors ntawm T cell nto. Muaj ntau ntau hom T hlwb uas muaj nyias lub luag haujlwm hauv lub cev tiv thaiv kab mob. Lawv muaj xws li pab T hlwb, nco T hlwb, cytotoxic T hlwb (killer T hlwb) thiab suppressor T hlwb. Helper T hlwb koom tes nrog B hlwb hauv kev tsim cov tshuaj tiv thaiv kab mob thiab ua kom cov macrophages thiab o. Killer T cells tua cov kab mob antigen (feem ntau yog cov kab mob kab mob), cov qog nqaij hlav cancer thiab cov hlwb txawv teb chaws ncaj qha. Qhov sib txawv tseem ceeb ntawm T pab hlwb thiab cov hlwb cytotoxic yog cov pab T hlwb koom nrog kev sib koom tes ntawm lub cev tiv thaiv kab mob tiv thaiv kab mob nrog B hlwb thiab lwm cov T hlwb thaum cytotoxic cells ncaj qha tua lossis rhuav tshem cov qog nqaij hlav cancer thiab cov kab mob antigen.

T Helper Cells yog dab tsi?

T pab hlwb (tseem hu ua CD4+ T hlwb) yog cov hlwb tseem ceeb uas tswj kev tiv thaiv kab mob tiv thaiv kab mob. T pab hlwb qhia lwm lub cev tiv thaiv kab mob xws li killer T hlwb, B hlwb, phagocytes (macrophages) thiab suppressor T hlwb los ntawm kev muab cov cim ua haujlwm tawm tsam cov kab mob. Ntau tus pab T hlwb xav tau rau txoj haujlwm no. Helper T hlwb ua tag nrho cov haujlwm no los ntawm kev zais cov protein me me hu ua T cell cytokines (ua kom cov proteins). Helper T hlwb pab txhawb los yog tswj lub cev tiv thaiv kab mob thiab. T pab hlwb kuj pab B hlwb thiab nco B hlwb rau maturation.

Qhov sib txawv ntawm T Helper thiab T Cytotoxic Cells
Qhov sib txawv ntawm T Helper thiab T Cytotoxic Cells

Daim duab 01: Lub luag haujlwm ntawm Pab Pawg T cells

Thaum T tus pab cell kuaj pom tus kab mob kis, nws qhib thiab faib ua ntau lub hlwb T pab. Cov txheej txheem no hu ua clonal expansion. Qee lub hlwb faib ua lub cim xeeb thaum lwm lub hlwb ua haujlwm sib txawv raws li hauv qab no los teb cov kab mob kis los ntawm kev tsim cov proteins hu ua cytokines.

  1. Ua kom cov neeg tua neeg tua cov kab mob tua kab mob ncaj qha.
  2. Txhawb nqa B hlwb los tsim cov tshuaj tiv thaiv kab mob kom lo nrog cov kab mob dawb.
  3. Txhawb nqa macrophages kom ua tau zoo hauv kev ntxuav cov kab mob tuag.
  4. Txhawb nqa suppressor T hlwb kom qeeb hauv lub cev tiv thaiv kab mob tom qab tus kab mob tawm tsam yog neutralized.

T Cytotoxic Cells yog dab tsi?

Cytotoxic T cells, tseem hu ua CD8+ T hlwb lossis tua T hlwb, yog ib hom T hlwb uas ncaj qha tua cov qog nqaij hlav cancer, cov kab mob kis kab mob thiab cov hlwb puas ntawm tsim qhov hauv cov phab ntsa ntawm tes. Thaum cov cell npog tau tawg, cov ntsiab lus ntawm tes xau tawm thiab rhuav tshem cov hlwb. Killer T hlwb nthuav qhia T cell receptors ntawm lub xov tooj ntawm tes kom paub txog antigens. Antigens khi rau chav kawm I MHC molecules. Yog li, cytotoxic T hlwb paub txog qhov kev hem thawj. Cytotoxic T cells tso granules uas muaj cov molecules tseem ceeb los tua cov kab mob.

Qhov txawv tseem ceeb - T Helper vs T Cytotoxic Cells
Qhov txawv tseem ceeb - T Helper vs T Cytotoxic Cells

Daim duab 02: Killer T cells nyob ib puag ncig lub hlwb

Ob hom molecules koom nrog cytotoxic T hlwb tua kev ua. Lawv yog perforin thiab granzymes. Granzymes yog proteases ua rau apoptosis. Perforin molecules tsim qhov los yog qhov hws hauv lipid bilayer.

Dab tsi zoo sib xws ntawm T Pab thiab T Cytotoxic Cells?

  • T pab hlwb thiab cytotoxic T hlwb yog cov qe ntshav dawb (leukocytes).
  • T pab thiab T cytotoxic hlwb yog ob hom T lymphocytes.
  • Ob leeg koom nrog kev tiv thaiv kev tiv thaiv.

Qhov txawv ntawm T Pab thiab T Cytotoxic Cells yog dab tsi?

T Pab vs T Cytotoxic Cells

T Pab cov hlwb yog cov T hlwb uas qhia B hlwb thiab lwm lub cev tiv thaiv kab mob los teb cov kab mob (kom txhim kho lub cev tiv thaiv kab mob). T Cytotoxic Cells yog T hlwb uas tua cov qog nqaij hlav cancer thiab cov kab mob kis ncaj qha los ntawm kev rhuav tshem cov cell membranes.
Tom qab kab mob
T Pab cov hlwb qeeb qeeb hauv lub cev tiv thaiv kab mob thaum tus kab mob ploj mus. T Cytotoxic Cells txuas ntxiv tua vim qhov ua kom.
T Pab hlwb muaj ntau lub luag haujlwm suav nrog kev txhawb nqa B hlwb, macrophages, suppressor T hlwb, ua kom cov neeg tua neeg T hlwb, thiab lwm yam. T Cytotoxic Cells muaj ib txoj haujlwm tseem ceeb uas yog tua cov antigens ncaj qha.
Muaj peev xwm tua tus kab mob ncaj qha
T Pab cov hlwb tsis tuaj yeem tua cov kab mob ncaj qha. T Cytotoxic Cells muaj peev xwm tua cov kab mob ncaj qha.

Summary – Helper T Cells vs Cytotoxic T Cells

Pab T hlwb thiab Cytotoxic T hlwb yog ob hom T cell. Helper T hlwb koom nrog kev sib koom ua ke ntawm kev tiv thaiv kab mob tiv thaiv kab mob. Cov hlwb no qhia thiab txhawb B hlwb, lwm cov T hlwb thiab macrophages ua lawv lub luag haujlwm tshwj xeeb. Cytotoxic T hlwb ncaj qha tua cov kab mob, cov qog nqaij hlav cancer thiab lwm cov hlwb puas. Qhov no yog qhov txawv ntawm T pab hlwb thiab cytotoxic T hlwb. Ob hom yog cov qe ntshav dawb tseem ceeb heev ntawm lub cev tiv thaiv kab mob.

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