Keratinocytes vs Melanocytes
Txhawm rau nkag siab qhov sib txawv ntawm keratinocytes thiab melanocytes, ib tus yuav tsum xub nkag siab txog lub cev ntawm daim tawv nqaij. Daim tawv nqaij yog lub cev loj tshaj plaws ntawm lub cev thiab ua ib qho kev cuam tshuam ntawm cov ntaub so ntswg hauv qab thiab ib puag ncig sab nraud. Daim tawv nqaij yog tsim los ntawm ob txheej; sab nrauv-tiv thaiv epidermis thiab inner-connective dermis. Epidermis muaj ob peb txheej ntawm cov hlwb epithelial thiab tsis muaj cov ntshav ncaj qha. Cov hlwb yog nourished los ntawm diffusion ntawm cov as-ham los ntawm cov hauv qab cov as-ham uas muaj ntshav txaus. Sab hauv epidermis muaj lub voos xwmfab zoo li, sib faib cov hlwb sai, thaum lub epidermis sab nrauv muaj cov hlwb tuag, uas tau tawm thiab tshem tawm sai ntawm lub cev. Dermis yog dag nyob rau hauv lub epidermis thiab yog tsim los ntawm ntau elastin thiab collagen fibers nrog rau cov ntshav txaus. Epidermis muaj plaub lub hlwb tshwj xeeb, uas yog; melanocytes, keratinocytes, Langerhans hlwb, thiab Grinstein hlwb. Tawm ntawm plaub lub hlwb, tsuas yog melanocytes thiab keratinocytes tau tham hauv kab lus no. Qhov sib txawv tseem ceeb ntawm keratinocytes thiab melanocytes yog tias keratinocytes tsim cov plaub hau thiab rau tes, thaum melanocytes yog lub luag haujlwm rau xim ntawm daim tawv nqaij. Ntxiv qhov sib txawv ntawm ob qho tib si, keratinocytes thiab melanocytes, tau tham kom ntxaws, hauv kab lus no
YKeratinocytes yog dab tsi?
Keratinocytes yog hom cell ntau tshaj plaws nyob rau hauv cov epidermis. Raws li lub npe qhia, keratinocytes tshwj xeeb hauv kev tsim cov keratin thiab cov keratinocytes tuag thaum kawg ua rau cov keratinized txheej ua plaub hau thiab rau tes. Ntxiv mus, keratinocytes cuam tshuam rau kev loj hlob ntawm T hlwb los ntawm kev zais IL-1 (tseem tsim los ntawm macrophages) thiab yog li keratinocytes pab txhawb kev tiv thaiv kab mob hauv lub cev.
Melanocytes yog dab tsi?
Melanocytes yog cov hlwb tshwj xeeb pom nyob rau hauv cov epidermis thiab feem ntau yog lub luag haujlwm rau kev tsim thiab tawg ntawm cov xim hu ua melanin, uas muab cov xim ntawm daim tawv nqaij ntawm ntau haiv neeg. Feem ntau, txhua haiv neeg muaj tib tus naj npawb ntawm melanocytes, tab sis tsuas yog vim li cas rau cov tawv nqaij sib txawv yog qhov sib txawv ntawm melanin uas tsim los ntawm txhua lub melanocyte. Tyrosinase enzyme nyob rau hauv melanocytes plays lub luag hauj lwm tseem ceeb nyob rau hauv lub complex biochemical txoj kev uas ua rau lub tsim ntawm melanin. Yog tias tyrosinase ua haujlwm tau zoo, cov tawv nqaij ua rau muaj xim tsaus heev. Txawm li cas los xij, hauv cov neeg uas muaj xim tawv nqaij sib dua, ob yam kab mob caj ces yog lub luag haujlwm los txo qis kev ua haujlwm ntawm tyrosinase; (a) ntau ntawm tyrosinase tseem nyob hauv daim ntawv tsis ua haujlwm thiab (b) tyrosinase kev ua haujlwm yog inhibited los ntawm ntau yam inhibitors. Raws li qhov tshwm sim ntawm ob yam no, melanin ntau lawm yog tsawg. Melanin yog cov xim tseem ceeb uas tuaj yeem nqus cov teeb meem UV rays tawm los ntawm Sun. Lub sij hawm ntev raug rau UV rays tsub kom zus tau tej cov melanin, yog li ua rau qhov chaw tsaus ntawm daim tawv nqaij.
Dab tsi yog qhov txawv ntawm Keratinocytes thiab Melanocytes?
• Tus nqi ntawm keratinocytes siab heev thaum piv rau cov melanocytes.
• Keratinocytes yog lub luag haujlwm rau kev tsim cov keratin, whereas melanocytes tsim melanin.
• Keratinocytes tsim cov plaub hau thiab rau tes, whereas melanocytes lub luag hauj lwm rau xim ntawm daim tawv nqaij.
• raug UV lub teeb txhawb kev tso tawm ntawm ∝-melanocyte stimulating hormone (∝-MSH) los ntawm keratinocytes thiab qhov no ∝-MSH txhawb cov neeg nyob sib ze melanocytes txhawm rau txhim kho kev tsim cov melanin.
• Keratinocytes muab kev tiv thaiv txhua yam thiab tseem ceeb hauv kev tiv thaiv kab mob. Melanocytes tiv thaiv daim tawv nqaij los ntawm teeb meem UV rays.
