Qhov sib txawv tseem ceeb ntawm synchronous thiab metachronous nyob ntawm lub sijhawm pib ntawm tus mob qog noj ntshav thib ob. Cov qog nqaij hlav Synchronous tsim nyob rau hauv 6 lub hlis ntawm kev kuaj mob thawj zaug mob qog noj ntshav, thaum cov qog nqaij hlav metachronous tshwm sim tom qab 6 lub hlis los ntawm kev kuaj mob thawj zaug.
mob qog noj ntshav yog ib yam mob tshwm sim los ntawm kev faib tawm ntawm tes tsis muaj zog. Kev loj hlob ntawm cov qog nqaij hlav txawv nyob ntawm seb hom mob qog noj ntshav. Cov qog nqaij hlav cancer kis mus rau hauv lossis cuam tshuam cov ntaub so ntswg nyob ze thiab tuaj yeem mus rau qhov chaw nyob deb ntawm lub cev los tsim cov qog tshiab hauv cov txheej txheem hu ua metastasis. Synchronous thiab metachronous qog noj ntshav yog ob hom mob qog noj ntshav thib ob tsim tom qab kuaj pom tus mob qog noj ntshav.
Dab tsi yog Synchronous?
Synchronous cancer yog lub xeev mob qog noj ntshav uas mob qog noj ntshav thib ob tau tsim nyob rau hauv 6 lub hlis ntawm thawj tus mob qog noj ntshav. Synchronous cancer tuaj yeem piav qhia txog kev mob qog nqaij hlav hauv plab, qhov twg nws hais txog qhov tshwm sim ntawm ntau tshaj ib qho mob qog nqaij hlav hauv plab hauv lub sijhawm 6 lub hlis. Feem ntau qhov chaw ntawm synchronous colorectal cancer yog thaj tsam ntawm txoj hnyuv thiab lub qhov quav. Txawm li cas los xij, qee qhov xwm txheej, ntau cov kab mob hauv plab hnyuv tau pom tau muab faib rau hauv cov hnyuv loj thiab cov cheeb tsam ze. Yog li, ntxiv adenomas tuaj yeem tshwm sim los ntawm kev txhim kho synchronous.
Cov noob caj noob ces ua lub luag haujlwm tseem ceeb hauv qhov pib ntawm kev mob qog noj ntshav synchronous. Kev hloov pauv thiab microsatellite tsis ruaj khov yog ob yam tseem ceeb uas txhawb nqa cov kab mob sib kis hauv tib neeg. Epigenetic mechanisms kuj tseem ua lub luag haujlwm tseem ceeb ntawm methylation los txhawb qhov pib ntawm cov qog nqaij hlav synchronous.
Metachronous yog dab tsi?
Metachronous cancer yog lub xeev ntawm mob qog noj ntshav uas mob qog noj ntshav thib ob tshwm sim tom qab 6 lub hlis ntawm qhov pib mob qog noj ntshav thawj zaug. Colorectal carcinoma kuj qhia tau hais tias kev txhim kho metachronous. Hauv qhov no, kev kuaj mob ntawm metachronous carcinoma yuav tsum tshwm sim tom qab 6 lub hlis ntawm kev kuaj mob qog noj ntshav. Lub synchronous xwm ntawm carcinoma tuaj yeem raug tshem tawm. Txawm li cas los xij, kev saib xyuas rov qab yuav tsum tau ua nyob rau lub sijhawm sib txawv hauv 1 xyoo, 3 xyoos, 10 xyoo, thiab lwm yam. Qhov no yuav tso cai rau saib xyuas qhov tseeb ntawm txhua qhov metastases uas tshwm sim los ntawm qhov pib mob qog noj ntshav thib ob.
Daim duab 01: Kab mob qog noj ntshav
Qhov kev txheeb xyuas tseem ceeb ntawm cov xwm txheej metachronous ntawm cov qog nqaij hlav hauv plab hnyuv loj yog kev txheeb xyuas cov kab mob metachronous hauv cov hnyuv loj, qhov quav, thiab cov hnyuv. Qhov tshwm sim ntawm kev mob qog noj ntshav synchronous loj hlob mus rau hauv metachronous cancer yog siab heev hauv kev mob qog noj ntshav. Txawm li cas los xij, qhov tshwm sim ntawm metachronous xwm muaj ntau dua hauv cov qog nqaij hlav hauv plab es tsis yog cov qog nqaij hlav synchronous.
Dab tsi yog qhov zoo sib xws ntawm Synchronous thiab Metachronous?
- Ob leeg muaj feem cuam tshuam txog qhov pib mob qog noj ntshav thib ob tom qab thawj tus mob qog noj ntshav.
- Lawv txiav txim siab caj ces.
- Ob leeg ua rau mob qog noj ntshav.
- Lawv tuaj yeem kuaj tau los ntawm kev kuaj biopsies lossis scopy tests.
- Ob leeg muaj ntau dua ntawm cov qog nqaij hlav hauv plab.
Qhov txawv ntawm Synchronous thiab Metachronous yog dab tsi?
Qhov sib txawv tseem ceeb ntawm synchronous thiab metachronous yog raws li qhov pib ntawm tus mob qog noj ntshav thib ob. Synchronous carcinoma tshwm sim nyob rau hauv 6 lub hlis ntawm qhov pib ntawm thawj thawj mob qog noj ntshav. Metachronous carcinoma tshwm sim tom qab 6 lub hlis ntawm qhov pib mob qog noj ntshav thawj zaug.
Cov lus hauv qab no qhia txog qhov sib txawv ntawm synchronous thiab metachronous.
Summary – Synchronous vs Metachronous
Synchronous thiab metachronous carcinomas ua rau mob qog noj ntshav. Synchronous carcinoma tshwm sim nyob rau hauv 6 lub hlis ntawm qhov pib ntawm thawj tus mob qog noj ntshav thaum lub sij hawm metachronous carcinoma tshwm sim tom qab 6 lub hlis txij thaum pib ntawm tus mob qog noj ntshav thib ob. Genetics plays lub luag haujlwm tseem ceeb hauv synchronous thiab metachronous carcinoma. Kev kuaj mob ntawm synchronous thiab metachronous carcinoma tshwm sim ntawm biopsies thiab scopy tests. Yog li, qhov no qhia txog qhov sib txawv ntawm synchronous thiab metachronous.
