Qhov sib txawv tseem ceeb ntawm cov dej ntws thiab cov dej ntws qis qis yog cov dej ntws tawm bioprocessing suav nrog kev tshuaj xyuas thiab txheeb xyuas cov kab mob, kev npaj tawm, kev faib cov microbes hauv bioreactor, thiab incubation, thaum downstream bioprocessing suav nrog extraction, purification thiab ntim ntawm cov khoom tshwm sim. los ntawm fermentation.
Bioprocesses siv cov kab mob muaj sia, tshwj xeeb tshaj yog cov kab mob xws li kab mob thiab cov fungi, los tsim cov khoom siv bioproducts uas tseem ceeb hauv kev lag luam lossis kev kho mob. Xws li bioproducts suav nrog tshuaj tua kab mob, vitamins, tshuaj hormones, enzymes, thiab organic acids. Feem ntau bioprocesses yog ua haujlwm hauv bioreactor. Fermentation yog ib lo lus siv feem ntau los hais txog bioprocess ua hauv bioreactor. Fermentation tuaj yeem muab faib ua ob txoj haujlwm tseem ceeb / theem raws li kev ua cov dej ntws thiab cov dej ntws. Tag nrho cov txheej txheem mus txog rau kev rho tawm ntawm cov khoom los ntawm bioreactor los ntawm cov txheej txheem ntws, thaum cov kauj ruam xws li kev rho tawm, purification, kev kuaj xyuas zoo, thiab ntim, thiab lwm yam, uas yog ua tiav tom qab txheej txheem fermentation, los ntawm cov txheej txheem qis.
Upstream Bioprocessing yog dab tsi?
txheej txheem dej ntws yog ib qho ntawm ob qhov tseem ceeb ntawm bioprocess. Nws suav nrog cov thawj kauj ruam ntawm cov txheej txheem fermentation. Kev npaj cov kab mob kab mob yog thawj kauj ruam ntawm kev nce dej bioprocessing. Qhov xav tau microbes yuav tsum raug cais tawm thiab xaiv rau bioprocess. Tom qab ntawd lawv yuav tsum tau coj mus rau hauv ib qho kev loj hlob nruab nrab. Kev npaj nruab nrab yog theem ob. Cov kev mob zoo tshaj plaws, ua ke nrog cov khoom noj khoom haus, yog muab rau kev loj hlob thiab kev sib npaug ntawm cov kab mob hauv lub bioreactor.
Daim duab 01: Bioprocessing
Kev npaj xov xwm thiab kev ua kom zoo ntawm kev loj hlob yog ob kauj ruam ntawm kev ua tiav bioprocessing. Inoculation thiab khiav ntawm bioreactors kom txog rau thaum tiav cov txheej txheem fermentation yog cov theem tom ntej ntawm bioprocessing nce toj.
Yuav ua li cas yog Downstream Bioprocessing?
Txoj kev bioprocessing yog hais txog ob peb kauj ruam kawg ntawm bioprocess uas koom nrog cov khoom sau. Cov txheej txheem downstream pib thaum cov khoom tsim tiav. Cov kauj ruam suav nrog kev rho tawm, ua kom huv, thiab ntim cov khoom siv bioproduct kawg ntawm bioprocess. Downstream bioprocessing tseem hu ua khoom rov qab. Amino acids, tshuaj tua kab mob, organic acids, vitamins, thiab tshuaj tiv thaiv yog ib co ntawm cov bioproducts tshwm sim los ntawm ib tug bioprocess. Qhov xav tau zoo ntawm bioproduct yog tiav thaum lub sij hawm downstream txheej txheem. Cov khoom lag luam tsis muaj zog tuaj yeem ua kom huv si siv cov txheej txheem distillation. Ntxiv mus, biomass sib cais tuaj yeem ua tau los ntawm centrifugation. Yog li ntawd, cov theem uas muaj kev sib cais, rho tawm, purification, thiab polishing yog downstream bioprocessing.
Dab tsi zoo sib xws ntawm Upstream thiab Downstream Bioprocessing?
- Upstream thiab downstream bioprocessing yog ob qhov tseem ceeb ntawm bioprocess.
- Cov kab mob nyob, tshwj xeeb tshaj yog cov kab mob, koom nrog ob txoj kev.
- Industrially thiab medicinally tseem ceeb bioproducts undergo cov txheej txheem.
- Ob txoj kev tseem ceeb sib npaug thaum tsim khoom bioproducts.
- Kev kis kab mob yuav tsum raug tiv thaiv thaum ob qho kev ua haujlwm.
Qhov txawv ntawm Upstream thiab Downstream Bioprocessing yog dab tsi?
Kev txhim kho cov khoom lag luam tshwm sim thaum lub sij hawm nce bioprocessing, thaum cov khoom sau qoob loo tshwm sim thaum lub sij hawm downstream bioprocessing. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm cov dej ntws thiab cov dej hauv qab bioprocessing. Ntxiv mus, kev sib cais thiab xaiv cov kab mob, kev loj hlob ntawm inoculum, media npaj, inoculation thiab incubation yog cov kauj ruam tseem ceeb ntawm upstream bioprocessing. Nyob rau hauv sib piv, extraction, purification, zoo xyuas thiab ntim ntawm cov khoom yog cov kauj ruam tseem ceeb ntawm downstream bioprocessing.
Cov lus hauv qab no qhia txog qhov sib txawv ntawm cov dej ntws thiab cov dej ntws qis rau kev sib piv ntawm ib sab.
Summary – Upstream vs Downstream Bioprocessing
Bioprocess lossis fermentation muaj ob theem tseem ceeb: cov dej ntws tawm bioprocessing thiab downstream bioprocessing. Nyob rau hauv cov dej ntws bioprocessing, microbes raug tshuaj xyuas, kab lis kev cai, thiab loj hlob hauv bioreactor, muab cov as-ham tsim nyog thiab kev loj hlob. Downstream bioprocessing pib thaum kawg ntawm lub sijhawm inoculation thaum lub fermentation tiav. Nyob rau hauv downstream bioprocessing, extraction, purification, thiab kom zoo packing ntawm cov khoom yog ua. Yog li, qhov no piav qhia txog qhov sib txawv ntawm cov dej ntws thiab cov dej ntws qis hauv bioprocessing.
