Qhov txawv ntawm heme thiab hemin yog tias heme muaj ferrous ion, hos hemin muaj ferric ion.
Heme thiab hemin yog porphyrin protein molecules. Cov no yog heterocyclic macromolecules uas peb tuaj yeem hu ua cov organic tebchaw.
Hem yog dab tsi?
Heme yog ib yam khoom siv biochemical uas tsim nyog los khi oxygen hauv cov hlab ntsha. Cov tshuaj no yog tsim los ntawm biosynthesis nyob rau hauv ob qho tib si pob txha pob txha thiab lub siab. Hauv kev teb ntawm microbiology, lo lus heme yog hais txog kev sib koom ua ke uas muaj cov hlau ion ua haujlwm rau porphyrin uas ua raws li tetradentate ligand thiab rau ib lossis ob lub axial ligands.
Daim duab 01: Oxygen Binding rau Heme Group
Feem ntau, hemoproteins, suav nrog heme, muaj ntau yam kev ua haujlwm lom neeg, xws li kev thauj mus los ntawm cov pa roj carbon diatomic, tshuaj catalysis, diatomic gas detection, thiab electron hloov. Heme hlau ua raws li lub hauv paus ntawm los yog dab dej ntawm electrons thaum lub sij hawm electron hloov los yog redox chemistry.
Muaj ntau hom heme molecules xws li heme A, heme B, heme C, thiab heme O. Cov molecules no muaj cov qauv tshuaj sib txawv thiab cov pab pawg ua haujlwm sib txawv. Ntawm cov hom no, heme B yog ntau hom, tab sis heme A thiab heme C kuj tseem ceeb sib npaug. Tsis tas li ntawd, tuaj yeem muaj qee yam tsis tshua muaj ntawm heme ib yam nkaus, uas suav nrog heme I, uas yog cov txiaj ntsig ntawm heme B uas covalently txuas rau cov protein seem ntawm lactoperoxidase. Ib yam li ntawd, heme M yog muab los ntawm heme B, uas zoo li kev sib raug zoo rau qhov chaw nquag ntawm myeloperoxidase. Heme D kuj yog ib qho derivative ntawm heme B, muaj xws li propionic acid sab saw ntawm C-6 txoj hauj lwm.
Thaum xav txog kev tsim cov heme proteins, txoj hauv kev enzymatic ntawm heme ntau lawm yog hu ua porphyrin synthesis, thiab ntawm no tag nrho cov intermediates yog tetrapyrroles uas yog tshuaj hu ua porphyrins.
Qhov degradation ntawm heme protein molecules pib hauv macrophages ntawm tus po, uas tuaj yeem tshem tawm cov laus thiab puas erythrocytes los ntawm kev ncig.
Hemin yog dab tsi
Hemin yog ib hom porphyrin uas muaj cov tshuaj chlorine, thiab nws tuaj yeem tsim los ntawm heme pawg, suav nrog heme B. Cov khoom sib txuas no yog hu ua protoporphyrin IX, thiab nws muaj ferric hlau ion uas muaj cov tshuaj chloride ligand. Hauv cov ntsiab lus tshuaj, hemin molecule txawv ntawm heme-compound hematin vim yog cov tshuaj chloride hauv hemin nyob rau hauv qhov chaw ntawm kev sib koom ua ke hydroxide ion hauv hematin.
Daim duab 02: Khoom Hemin
Cov tshuaj no yog tsim nyob rau hauv peb tib neeg lub cev endogenously, xws li. thaum lub sijhawm hloov pauv ntawm cov qe ntshav liab qub. Txawm li cas los xij, cov tshuaj no tuaj yeem tsim los ntawm hemolysis lossis vascular raug mob. Ntxiv mus, ntau cov proteins hauv tib neeg cov ntshav kuj khi rau hemin, xws li. hemopexin thiab serum albumin.
Hmoob thiab Hemin yog dab tsi?
- Heme thiab hemin yog organic compounds.
- Ob leeg yog kev sib koom ua ke.
- Lawv muaj hlau ions.
Qhov txawv ntawm Heme thiab Hemin yog dab tsi?
Heme thiab hemin yog porphyrin protein molecules. Heme yog ib hom tshuaj biochemical uas tsim nyog los khi cov pa oxygen hauv cov hlab ntsha thaum hemin yog hom porphyrin uas muaj cov tshuaj chlorine uas tuaj yeem tsim los ntawm pawg heme, suav nrog heme B. Qhov sib txawv tseem ceeb ntawm heme thiab hemin yog tias heme muaj ferrous ion, hos hemin muaj ferric ion. Tsis tas li ntawd, heme tsis muaj chloride atoms, thaum hemin muaj chloride atoms.
Hauv qab no yog cov ntsiab lus ntawm qhov sib txawv ntawm heme thiab hemin hauv daim ntawv tabular.
Summary – Heme vs Hemin
Heme thiab hemin yog porphyrin protein molecules. Qhov sib txawv tseem ceeb ntawm heme thiab hemin yog tias heme muaj ferrous ion, hos hemin muaj ferric ion. Tsis tas li ntawd, hemin molecules muaj chloride atoms hauv cov qauv tshuaj, qhov heme tsis muaj chloride atoms.
