Qhov sib txawv tseem ceeb ntawm DNA-RNA hybrids thiab dsDNA yog DNA-RNA hybrids yog ob-stranded nucleotides tsim los ntawm ib tug DNA strand thiab ib tug ntxiv RNA strand thaum dsDNA yog ib tug ob-stranded DNA muaj li ntawm ob complementary DNA strands..
Nyob rau hauv nws lub xeev, DNA yog ob-stranded. Nws muaj ob qhov sib ntxiv DNA strands sib txuas los ntawm hydrogen bonds. RNA yog ib leeg-stranded nyob rau hauv nws haiv neeg qauv. Hauv qee qhov, RNA tsim duplexes nrog DNA. Lawv hu ua DNA-RNA hybrids. Lawv tsuas yog tsim thaum lub sij hawm transcription thiab multiplication ntawm oncogenic RNA kab mob. Hauv kev sib piv rau dsDNA, DNA-RNA hybrids ruaj khov dua.
DNA-RNA Hybrids yog dab tsi?
DNA-RNA hybrids yog nucleic acids tsim los ntawm ib qho DNA strand thiab ib qho ntxiv RNA strand. Lawv tsim thaum sau ntawv thaum RNA thiab DNA nyob ze. Ntxiv mus, DNA-RNA hybrids tsim thaum lub sij hawm sib npaug ntawm cov kab mob oncogenic RNA.
Daim duab 01: DNA-RNA Hybrids
Feem ntau, DNA-RNA hybrids muaj ntau nyob rau hauv tib neeg lub hlwb. Lawv ruaj khov dua ob-stranded DNA. Thaum DNA-RNA hybrids raug tsim, ib DNA strand hloov chaw. Nws yog lub npe hu ua R voj. Cov R loops no feem ntau deleterious vim lawv tuaj yeem ua rau DNA puas.
DsDNA yog dab tsi?
dsDNA lossis ob-stranded DNA yog nucleic acid uas muaj ob DNA strands. Cov DNA ob kab no yog sib txuas ntxiv rau ib leeg. Tsis tas li ntawd, lawv cua ib puag ncig zoo li tus ntaiv twisted. Cov pob txha ntawm ob txoj hlua muaj qab zib thiab phosphate pawg.
Daim duab 02: dsDNA
Muaj plaub qhov sib txawv nitrogenous hauv paus xws li A, G, C thiab T. Ob txoj hlua khi rau ib leeg los ntawm hydrogen bonds tsim ntawm cov hauv paus. Adenine tsim ib khub nrog thymine. Cytosine tsim ib khub nrog guanine. Tus qauv ntawm DNA helix tau piav qhia los ntawm Watson thiab Crick hauv xyoo 1953. Qhov DNA ob lub helix no muaj cov ntaub ntawv keeb kwm ntawm lub cev. DNA tuaj yeem rov ua dua thiab kho dua. Feem ntau DNA ob lub helices yog sab xis. Ntxiv mus, dsDNA yog anti-parallel. Yog li ntawd, 5' kawg ntawm ib txoj hlua khi nrog 3' kawg ntawm lwm txoj hlua.
Dab tsi yog qhov zoo sib xws ntawm DNA-RNA Hybrids thiab dsDNA?
- DNA-RNA hybrids thiab dsDNA yog nucleic acids.
- Ob leeg DNA-RNA hybrids thiab dsDNA yog ob-stranded, tsim los ntawm ob qho ntxiv polynucleotide strands.
- Ob txoj kab ntawm DNA-RNA hybrids thiab dsDNA txuas nrog hydrogen bonds.
Dab tsi yog qhov txawv ntawm DNA-RNA Hybrids thiab dsDNA?
DNA-RNA hybrids yog nucleic acids tsim los ntawm DNA strand thiab ntxiv RNA strand, thaum dsDNA yog nucleic acid tsim los ntawm ob qho ntxiv DNA strands. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm DNA-RNA hybrids thiab dsDNA.
Ntxiv mus, lwm qhov sib txawv tseem ceeb ntawm DNA-RNA hybrids thiab dsDNA yog tias DNA-RNA hybrids ruaj khov dua li dsDNA.
Hauv qab infographic qhia qee qhov sib txawv tseem ceeb ntawm DNA-RNA hybrids thiab dsDNA.
Summary – DNA-RNA Hybrids vs dsDNA
DNA-RNA hybrids thiab dsDNA yog ob hom nucleic acids uas tsim los ntawm polynucleotides. Ob leeg yog ob-stranded. Txawm li cas los xij, DNA-RNA hybrids muaj ib DNA strand thiab ib RNA strand thaum dsDNA muaj ob DNA strands. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm DNA-RNA hybrids thiab dsDNA. DNA-RNA hybrids yog tsim thaum lub sij hawm transcription. Ntxiv mus, lawv ruaj khov dua dsDNA.
