Qhov sib txawv tseem ceeb ntawm amide thiab peptide daim ntawv cog lus yog qhov amide daim ntawv cog lus ntawm ib pawg hydroxyl thiab ib pawg amino ntawm ob lub molecules whereas peptide daim ntawv cog lus ntawm ob amino acid molecules thaum tsim cov saw peptide.
Amide bonds thiab peptide bonds yog biochemical bonds uas tsim ntawm cov pa roj carbon atom thiab nitrogen atom ntawm ob cais molecules. Feem ntau, cov ntawv cog lus no tsim ntawm ob lub amino acid molecules.
Amide Bonds yog dab tsi?
Amide daim ntawv cog lus yog ib hom kev cog lus cog lus uas tsim cov amide ua cov khoom kawg. Muaj peb hom amides loj xws li carboxamides, sulfonamides, thiab phosphoramides. Txawm li cas los xij, qhov yooj yim amides yog cov khoom siv ntawm ammonia.
Daim duab 01: Txawv Amide Bonds
Amides feem ntau suav tias yog lub hauv paus tsis muaj zog thaum piv rau amines. Yog li, cov tshuaj no tsis qhia cov kua qaub-puag hauv dej. Ib daim ntawv cog lus peptide yog ib hom amide daim ntawv cog lus. Ntawm no, daim ntawv cog lus amide thaum pawg carboxylic acid ntawm ib cov amino acid reacts nrog cov amine pawg ntawm lwm cov amino acid. Covalent daim ntawv cog lus tsim los ntawm kev tshem tawm cov dej molecule. Yog li ntawd, nws yog ib tug condensation tshuaj.
Peptide Bonds yog dab tsi?
Ib daim ntawv cog lus peptide yog ib hom covalent daim ntawv cog lus uas tsim ntawm ob amino acids. Ib daim ntawv cog lus peptide tsim ntawm cov pa roj carbon atom ntawm ib qho amino acid thiab nitrogen atom ntawm cov amino acid uas tshwm sim nrog kev tshem tawm ntawm cov dej molecule. Thaum xav txog cov qauv hauv paus ntawm cov amino acid, nws muaj lub hauv paus carbon atom txuas nrog pawg carboxylic, amino pawg, hydrogen atom thiab alkyl pawg. Feem ntau, cov amino acids txawv ntawm ib leeg raws li cov qauv ntawm pawg alkyl.
Thaum lub sijhawm tsim ntawm daim ntawv cog lus peptide, cov tshuaj tiv thaiv condensation tshwm sim ntawm ob amino acids. Ntawm no, carboxylic acid ntawm ib qho amino acid reacts nrog amine pawg ntawm lwm cov amino acid, tso ib tug dej molecule. Cov pawg -OH ntawm pawg carboxylic acid tsim cov dej molecule, sib txuas nrog hydrogen los ntawm pawg amine.
Peb tuaj yeem ua luv luv peptide daim ntawv cog lus raws li -CONH- daim ntawv cog lus vim tias daim ntawv cog lus uas muaj feem cuam tshuam nrog plaub lub atom. Thaum ob lub amino acids khi rau ib leeg los ntawm ib daim ntawv cog lus peptide, cov khoom kawg yog dipeptide. Txawm li cas los xij, yog tias ob peb cov amino acids khi nrog ib leeg, ces cov ntaub ntawv oligopeptide. Yog tias muaj pes tsawg tus amino acids khi nrog ib leeg los ntawm peptide bonds, cov molecule complex yog polypeptide.
Ib daim ntawv cog lus peptide tuaj yeem ua rau cov tshuaj tiv thaiv hydrolysis. Lub hydrolysis rhuav tshem daim ntawv cog lus, cais ob amino acids. Txawm tias cov txheej txheem qeeb heev, hydrolysis yuav tshwm sim nyob rau hauv lub xub ntiag ntawm dej.
Qhov txawv ntawm Amide thiab Peptide Bond yog dab tsi?
Amide thiab peptide bonds yog biochemical bonds. Qhov sib txawv tseem ceeb ntawm amide thiab peptide daim ntawv cog lus yog tias amide daim ntawv cog lus ntawm ib pawg hydroxyl thiab ib pawg amino ntawm ob lub molecules whereas peptide daim ntawv cog lus ntawm ob amino acid molecules thaum tsim cov saw peptide.
Hauv qab infographic qhia txog qhov sib txawv ntawm amide thiab peptide daim ntawv cog lus.
Summary – Amide vs Peptide Bond
Hauv biochemistry, amide bonds thiab peptide bonds ua lub luag haujlwm tseem ceeb hauv kev tsim cov protein molecule. Qhov sib txawv tseem ceeb ntawm amide thiab peptide daim ntawv cog lus yog tias amide daim ntawv cog lus ntawm ib pawg hydroxyl thiab ib pawg amino ntawm ob lub molecules thaum peptide daim ntawv cog lus ntawm ob amino acid molecules thaum tsim cov saw peptide.
