Qhov sib txawv tseem ceeb ntawm LD50 thiab LC50 yog tias LD50 sawv cev rau cov koob tshuaj tuag, qhov LC50 sawv cev rau kev ua kom tuag taus.
Cov ntsiab lus LD50 thiab LC50 feem ntau pom hauv toxicology. Cov no yog cov kev txwv rau cov tshuaj sib txawv uas piav qhia txog cov khoom uas tuaj yeem ua rau tuag taus. Ob qhov kev ntsuas no ntsuas qhov ua rau tuag taus ntawm ib yam khoom thaum nws raug rau cov pejxeem thiab ua rau tuag ntawm 50% ntawm cov pejxeem. Yog li, qhov no yog txoj kev denotation ntawm cov ntsiab lus tshwm sim. Piv txwv li, LD50 txhais tau hais tias cov koob tshuaj uas tuaj yeem ua rau 50% tuag thaum raug rau qee cov pejxeem.
LD50 yog dab tsi?
LD50 sawv cev rau Lethal Dose ntawm cov tshuaj uas tuaj yeem ua rau 50% tuag thaum raug rau cov pejxeem. Hauv lwm lo lus, tus nqi ntawm LD50 muab tus nqi ntawm cov khoom uas peb xav tau los tua ib nrab ntawm cov pejxeem. Ntawm no, cov khoom uas peb xav txog qhov toxicity feem ntau yog cov tshuaj lom, hluav taws xob lossis kab mob.
Feem ntau, LD50 yog qhov taw qhia zoo rau kev ntsuas qhov mob toxicity. Yog tias peb muaj tus nqi qis rau LD50, ces nws txhais tau hais tias cov khoom muaj zog toxicity. Ib yam li ntawd, yog tias tus nqi peb tau txais rau LD50 yog siab, ces qhov toxicity ntawm cov khoom ntawd tsawg. Qhov no yog vim qhov qis LD50 tus nqi txhais tau tias me ntsis ntawm cov tshuaj tuaj yeem tua ib nrab ntawm cov pejxeem, uas ua rau nws muaj tshuaj lom ntau dua.
Feem ntau, tus nqi rau LD50 yog muab raws li qhov loj ntawm cov khoom hauv ib chav tsev ntawm qhov kev xeem (i.e. cov pejxeem ntses hauv dej). Tom qab ntawd, chav tsev yog siv li milligrams ntawm cov khoom ib kilogram ntawm cov pejxeem. Txawm li cas los xij, chav tsev yuav txawv raws li hom neeg uas peb tab tom tham txog, piv txwv li rau kab lis kev cai kab mob, peb yuav tsum siv nanogram nplai. Ntxiv mus, qhov kev tuag no feem ntau txawv nrog txoj kev tswj hwm. Piv txwv li, cov tshuaj toxicity feem ntau yog tsawg thaum nws yog siv rau qhov ncauj es tsis txhaj.
Raws li kev hloov pauv, qhov tsis sib xws LD50/30 thiab LD50/60 kuj tseem ceeb. LD50/30 yog hais txog tus nqi ntawm cov tshuaj uas yuav ua rau tuag taus rau 50% ntawm cov pej xeem nyob rau hauv 30 hnub ntawm kis thiab LD50/60 hais txog nws yog 6o hnub ntawm raug.
LC50 yog dab tsi?
LC50 stands for Lethal Concentration ntawm ib yam khoom uas tuaj yeem ua rau 50% tuag thaum raug rau cov pejxeem. Feem ntau, qhov ntsuas no yog qhov tseem ceeb txog cov tshuaj lom neeg muaj feem xyuam nrog dej (vim peb tab tom tham txog cov concentrations).
Ntxiv mus, qhov ntsuas no tseem ceeb rau kev txiav txim siab qib ntawm kev mob toxicity. Chav tsev ntawm kev ntsuas ntawm concentration rau kev txiav txim siab ntawm LC50 feem ntau yog milligrams ib cubic meter los yog ppm (qhov ib lab).
Qhov txawv ntawm LD50 thiab LC50 yog dab tsi?
Qhov sib txawv tseem ceeb ntawm LD50 thiab LC50 yog tias LD50 sawv cev rau cov koob tshuaj tuag, qhov LC50 sawv cev rau kev ua kom tuag taus. LD50 yog hais txog Lethal Dose ntawm ib yam khoom uas tuaj yeem ua rau 50% tuag thaum raug rau cov pejxeem thaum LC50 hais txog Lethal Concentration ntawm cov khoom uas tuaj yeem ua rau 50% tuag thaum raug cov pejxeem.
Tsis tas li ntawd, peb tuaj yeem txiav txim siab LD50 tus nqi ntawm txhua yam khoom xav tau tab sis feem ntau, LC50 tau txiav txim siab txog cov tshuaj lom ntawm cov khoom hauv dej. Tsis tas li ntawd, chav ntsuas ntawm LD50 yog milligrams ntawm cov khoom ib kilogram ntawm cov pejxeem whereas chav tsev rau LC50 yog milligrams ib cubic meter los yog ppm (ib feem ib lab).
Cov lus qhia hauv qab no qhia txog qhov sib txawv ntawm LD50 thiab LC50.
Summary – LD50 vs LC50
Cov ntsiab lus LD50 thiab LC50 feem ntau pom hauv toxicology. Cov no yog cov kev txwv rau cov tshuaj sib txawv uas piav qhia txog cov khoom uas tuaj yeem ua rau tuag taus. Qhov sib txawv tseem ceeb ntawm LD50 thiab LC50 yog tias LD50 yog hais txog cov koob tshuaj tuag ntawm cov tshuaj uas tuaj yeem ua rau 50% tuag thaum raug rau cov pejxeem thaum LC50 hais txog qhov tuag taus ntawm cov khoom uas tuaj yeem ua rau 50% tuag thaum raug rau cov pejxeem..
