Qhov Tseem Ceeb Qhov txawv - Endotoxin vs Pyrogen
Pyrogen yog ib yam khoom uas ua rau kub taub hau tom qab tso rau hauv cov ntshav. Lawv raug tsim los ua cov khoom ntawm cov txheej txheem microbial metabolic. Pyrogens yog tsim los ntawm cov kab mob xws li kab mob, pwm, thiab cov poov xab. Cov kab mob thiab lwm yam khoom siv metabolic kuj ua raws li pyrogens. Endotoxins yog ib yam tseem ceeb ntawm pyrogens. Lawv yog cov tshuaj lom uas tsim los ntawm cov kab mob gram tsis zoo. Lawv yog lipopolysaccharides thiab yog nyob rau hauv lub txheej membrane ntawm cov kab mob ntawm tes. Yog li ntawd, lawv ua ib feem ntawm cov kab mob ntawm tes. Qhov sib txawv tseem ceeb ntawm endotoxin thiab pyrogen yog tias endotoxin yog lipopolysaccharide pom nyob rau hauv daim nyias nyias ntawm cov kab mob gram tsis zoo thaum pyrogen yog polypeptide lossis polysaccharide uas ua rau kub taub hau thaum tso tawm mus rau hauv kev.
Endotoxin yog dab tsi?
Cov kab mob sab nrauv ntawm cov kab mob gram tsis zoo yog feem ntau muaj lipopolysaccharides. Lipopolysaccharide molecules yog cov endotoxins tsim los ntawm cov kab mob. Lipopolysaccharide molecule muaj peb yam: lipid A, polysaccharide thiab O antigens. Cov tshuaj toxicity ntawm endotoxin yog txuam nrog lipid A tivthaiv ntawm lipopolysaccharide. Endotoxins suav hais tias yog ib feem ntawm cov kab mob ntawm tes. Lawv raug tso tawm thaum lub sij hawm cov kab mob cell phab ntsa disintegration. Ib feeb ntawm cov tshuaj endotoxins tuaj yeem raug tso tawm los ntawm cov kab mob loj zuj zus gram tsis zoo. Cov kab mob endotoxin uas tsim cov kab mob no yog Escherichia coli, Salmonella, Shigella, Pseudomonas, Neisseria, Haemophilus influenzae, Bordetella pertussis thiab Vibrio cholera.
Daim duab 01: Endotoxins
Endotoxins yog cov cua sov ruaj khov molecules nrog qhov hnyav dua molecular. Yog li ntawd, lawv tsis tuaj yeem rhuav tshem los ntawm kev npau taws. Cov tshuaj oxidizing muaj zog yog siv los rhuav tshem endotoxins. Endotoxins muaj qhov tshwj xeeb, tsis tshua muaj antigenic, thiab tsis muaj zog. Txawm li cas los xij, endotoxins pom muaj pyrogenicity siab. Endotoxins tsis tuaj yeem hloov mus rau toxoids.
YPyrogen yog dab tsi?
Pyrogen yog ib yam khoom lossis tus neeg sawv cev uas tuaj yeem ua rau kub taub hau lossis nce lub cev kub thaum tso tawm lossis nkag mus rau hauv cov ntshav. Pyrogens yog tsim los ntawm cov kab mob sib txawv xws li kab mob, kab mob, fungi, thiab lwm yam. Lawv tuaj yeem ua rau endogenous lossis exogenous. Qee cov pyrogens yog cov protein uas tsis muaj qhov hnyav molecular uas tsim los ntawm phagocytic leukocytes hauv cov lus teb rau cov pyrogens sab nraud. Exogenous pyrogens muaj keeb kwm sab nraud. Lawv tuaj yeem yog exotoxins tsim los ntawm cov kab mob lossis lwm yam khoom siv microbial. Endotoxins yog ib hom pyrogens tseem ceeb uas yog lipopolysaccharides. Antigen antibody complexes kuj yog ib hom pyrogens uas yog exogenous. Qee cov kab mob ua haujlwm li pyrogens. Cov ntshav tsis sib xws thiab cov khoom siv ntshav kuj suav tias yog pyrogens uas ua rau kub taub hau.
Daim duab 02: Interleukin 1 yog ib qho loj Endogenous Pyrogen
Pyrogens suav nrog polypeptides thiab polysaccharides. Feem ntau, pyrogen muaj qhov hnyav molecular. Lawv feem ntau yog los ntawm cov khoom ntawm cov txheej txheem metabolic ntawm cov kab mob. Txawm li cas los xij, muaj cov pyrogens uas tsis muaj microbial keeb kwm. Piv txwv li, hluavtaws polynucleotides uas suav tias yog pyrogens tsis yog los ntawm cov kab mob.
Dab tsi zoo sib xws ntawm Endotoxin thiab Pyrogen?
- Endotoxins thiab pyrogens ua rau kub taub hau.
- ob leeg yog tsim los ntawm cov kab mob.
- Ob leeg pyrogen thiab endotoxins yog cov cua sov ruaj khov.
Qhov txawv ntawm Endotoxin thiab Pyrogen yog dab tsi?
Endotoxin vs Pyrogen |
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| Endotoxin yog ib feem ntawm gram negative bacterial cell phab ntsa uas yog lom. | Pyrogen yog txhua yam ua npaws ua rau kub taub hau lossis tus neeg sawv cev. |
| Endotoxin yog lipopolysaccharide. | YPyrogen tuaj yeem yog polypeptide lossis polysaccharide. |
| ntau lawm | |
| Endotoxins yog tsim los ntawm cov kab mob, tshwj xeeb tshaj yog cov kab mob gram negative. | Pyrogens yog tsim los ntawm cov kab mob, kab mob, pwm, thiab cov poov xab. |
| Endotoxins yog endogenous. | YPyrogens tuaj yeem yog endogenous lossis exogenous. |
Summary – Endotoxin vs Pyrogen
Pyrogen yog ib yam khoom lossis tus neeg sawv cev uas ua rau kub taub hau, thaum tso rau hauv cov ntshav. Pyrogens yog tsim los ntawm ntau hom kab mob xws li kab mob, pwm, poov xab, thiab kab mob. Feem ntau ntawm cov co toxins uas tsim los ntawm cov kab mob yog kub taub hau-inducing tshuaj xws li exotoxins, neurotoxins, endotoxins. Endotoxins yog ib hom pyrogens tsim los ntawm cov kab mob gram tsis zoo. Lawv yog cov tshuaj lom lipopolysaccharides. Lawv yog ib feem ntawm cov txheej membrane ntawm gram negative bacteria. Qhov sib txawv tseem ceeb ntawm endotoxin thiab pyrogen yog tias endotoxin yog lipopolysaccharide uas ua rau muaj kev cuam tshuam tsis zoo xws li kub taub hau thaum pyrogens yog polysaccharides lossis polypeptides uas ua rau kub taub hau.
Download PDF Version of Endotoxin vs Pyrogen
Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline hom phiaj raws li cov ntawv sau tseg. Thov download PDF version ntawm no Qhov txawv Ntawm Endotoxin thiab Pyrogen.
