Qhov sib txawv tseem ceeb ntawm cov protomers thiab capsomeres yog cov protomers yog cov qauv ntawm cov proteins oligomeric thaum capsomeres yog cov proteins uas muaj cov protomers, uas yog cov qauv subunits ntawm viral capsid.
Tus kab mob yog ib qho kab mob hauv lub cev, uas yog kab mob sib kis. Lub capsid yog ib qho ntawm ob qho tseem ceeb ntawm cov kab mob. Nws yog lub tsho tiv thaiv protein uas nyob ib puag ncig thiab tiv thaiv kab mob genome. Lub capsid suav nrog cov protomers, uas yog cov qauv ntawm cov protein oligomeric. Capsomere yog ib qho qauv subunit ntawm tus kab mob capsid, thiab nws yog ib qho kev sib sau ntawm ntau tus protomers ua ib chav tsev. Yog li, protomers nws tus kheej sib sau ua ib lub capsomere thiab capsomeres nws tus kheej sib sau ua ib lub capsid.
Protomers yog dab tsi?
Protomers yog cov qauv ntawm cov protein oligomeric. Protomer muaj tsawg kawg yog ob txoj hlua sib txawv polypeptide. Feem ntau, lawv muaj ntau polypeptides. Hauv cov kab mob capsids, protomers nws tus kheej sib sau ua ke los tsim cov capsids, uas yog cov morphological units ntawm capsids. Protomers txuas nrog ib leeg los ntawm cov nyiaj tshwj xeeb thiab sib sau ua tus kheej.
Daim duab 01: Protomers
Nyob rau hauv cov kab mob luam yeeb mosaic, cov neeg ua haujlwm sib sau ua ke los tsim ob txheej txheej disc los qhwv RNA genome. Yog li, cov protomers ntawm haus luam yeeb mosaic kab mob thaum kawg tsim ib tug ntev ntev hollow raj, uas muab nws ib tug helical tsos. Hauv icosahedral symmetry, protomers sib sau ua ke ntawm tsib los yog rau lub capsomeres thiab tom qab ntawd condense rau hauv 20 lub ntsej muag ntawm daim duab peb sab sib npaug thiab 20 apices.
Cassomeres yog dab tsi?
Capsomeres yog cov txheej txheem protein subunits ntawm tus kab mob capsid. Lawv kuj yog cov morphological subunits ntawm cov kab mob. Raws li txoj cai, lub capsid yog kev sib sau ua ke ntawm capsomeres. Txhua lub capsomere muaj ntau tus protomers nws tus kheej sib sau ua ke. Tsis tas li ntawd, capsomeres tau npaj sib txawv hauv capsid los muab cov duab rau tus kab mob capsid. Hauv qhov no, helical, icosahedral thiab complex yog peb hom capsomere kev npaj hauv cov kab mob. Txawm li cas los xij, kev npaj ntawm capsomeres yog tus yam ntxwv ntawm tus kab mob tshwj xeeb. Capsomeres koom nrog ib leeg ntawm intercapsomeric triplexes muaj ob daim ntawv luam ntawm ib qho protein thiab ib daim ntawv ntawm lwm tus.
Daim duab 02: Capsomeres
Tsis tas li ntawd, txhua tus kab mob muaj tus lej kawg ntawm capsomeres. Tus kab mob siab B muaj icosahedral capsid muaj 180 capsomeres. Recombinant adenovirus muaj lub capsid muaj 252 capsomeres. Herpesviruses muaj 162 capsomeres hauv lawv cov capsids. Ntxiv mus, enterovirus muaj 60 capsomeres hauv nws capsid. Ib yam li ntawd, cov kab mob sib txawv muaj ntau tus naj npawb ntawm capsomeres hauv lawv lub plhaub protein.
Capsomeres ua tiav ntau lub luag haujlwm hauv cov kab mob. Capsomeres tiv thaiv tus kab mob genome los ntawm lub cev, tshuaj lom neeg thiab kev puas tsuaj ntawm cov enzymatic. Ntxiv mus, capsomeres yog ib qho tseem ceeb hauv kev qhia tus kab mob genome rau hauv tus tswv tsev los ntawm adsorbing nkag mus rau tus tswv tsev ntawm tes.
Dab tsi yog qhov zoo sib xws ntawm Protomers thiab Capsomeres?
- Protomers thiab capsomeres yog cov qauv protein.
- Protomers yog subunits ntawm capsomeres thaum capsomeres yog subunits ntawm viral capsid.
- Ob leeg protomers thiab capsomeres tuaj yeem ua tus kheej.
Qhov txawv ntawm Protomers thiab Capsomeres yog dab tsi?
Protomers yog cov qauv tsim ua cov proteins oligomeric thaum capsomeres yog cov morphological units ntawm viral capsids. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm protomers thiab capsomeres. Tsis tas li ntawd, protomers aggregate tsim capsomeres thaum capsomeres aggregate los ua capsid.
Hauv qab infographic qhia txog qhov sib txawv ntawm protomers thiab capsomeres.
Summary – Protomers vs Capsomeres
Protomers yog subunits ntawm capsomeres thaum capsomeres yog protein subunits ntawm viral capsid. Yog li, capsomere yog kev sib sau ntawm protomers thaum capsid yog kev sib sau ntawm capsomeres. Kev npaj ntawm protomers los yog kev npaj ntawm capsomeres muab cov duab los yog symmetry rau ib tug kab mob. Raws li kev npaj capsomere, helical thiab icosahedral yog ob daim duab los yog symmetries pom hauv cov kab mob. Yog li, qhov no qhia txog qhov txawv ntawm protomers thiab capsomeres.
