Qhov sib txawv tseem ceeb ntawm cohesin thiab condensin yog tias cohesin yog tetrameric protein complex uas tuav cov viv ncaus chromatids nruj ua ke thaum condensin yog pentameric protein complex xav tau rau chromosome condensation.
Cohesin thiab condensin yog ob lub ntsiab lus protein ntau uas tseem ceeb hauv kev sib cais ntawm tus muam chromatid hauv kev faib cell. Cohesin yog qhov tseem ceeb thaum lub sij hawm metaphase, thaum condensin tseem ceeb thaum lub sij hawm anaphase. Thaum mus los ntawm metaphase mus rau anaphase, condensin hloov cohesin thiab tso cai rau tus muam chromatids mus txog lawv cov ncej. Kev tsim qauv thiab ua haujlwm, ob qho proteins no txawv ntawm ib leeg.
Cohesin yog dab tsi?
Cohesin yog cov protein uas tuav cov viv ncaus chromatids ua ke tom qab DNA rov ua dua kom txog thaum anaphase tshwm sim, thiab nws yog lub sijhawm los cais tus muam chromatids ntawm ib leeg. Raws li txoj cai, cohesin yog ntau subunit protein complex uas yeej muaj plaub core subunits. Tawm ntawm plaub lub subunits, ob yog SMC proteins (SMC1 (cov qauv kev saib xyuas ntawm chromosome protein 1) thiab SMC3 (cov qauv kev saib xyuas ntawm chromosome protein 3), uas muaj ob lub ntsiab structural domains li lub taub hau thiab pob khawm. -coil molecules. Vim yog cohesin protein, tus muam chromatids cais mus rau ob tug ncej kom raug. Txwv tsis pub, cov hlwb tsis tuaj yeem tswj kev cais cov viv ncaus chromatids rau hauv txhua tus ncej thaum lub sij hawm anaphase.
Daim duab 01: Cohesin
Cohesin kuj pab txhawb kev txuas ntawm spindle fibers rau chromosomes. Tsis tas li ntawd, cohesin mediates kho DNA los ntawm recombination.
Condensin yog dab tsi?
Condensin yog pentameric protein complex xav tau rau chromosome condensation. Nws muaj tsib subunits, suav nrog ob SMC proteins thiab peb pab subunits. SMC proteins hauv condensing yog SMC2 thiab SMC4. Condensin ua tiav ntau lub luag haujlwm hauv kev tswj hwm genome, suav nrog kev faib mitotic thiab meiotic, kho DNA, tswj kev hloov pauv, thiab chromosome condensation.
Daim duab 02: Condensins
Muaj ob hom condensins li condensin I thiab condensin II. Condensin I tswj lub sij hawm ntawm chromosome condensation thaum condensin II pab txhawb kev compaction ntawm chromosome loops raws tus muam chromatid axes.
Dab tsi zoo sib xws ntawm Cohesin thiab Condensin?
- Cohesin thiab condensin yog cov proteins uas ua raws li kev sib txuas ntawm molecular.
- Ob qho tib si cohesion thiab condensin muaj txiaj ntsig hauv kev sib cais chromosome.
- Lawv kuj tseem ceeb rau mitotic chromosome architecture, kev cai ntawm tus muam chromatid khub, DNA kho thiab rov ua dua, thiab cov kev cai ntawm cov noob qhia.
- Lawv yog cov txheeb ze thiab cov txheeb ze.
- Ob leeg yog cov khoom sib xyaw ua ke.
- SMC proteins yog cov khoom ntawm ob qho tib si cohesion thiab condensin.
- Lawv yog lub nplhaib zoo li molecules.
Qhov txawv ntawm Cohesin thiab Condensin yog dab tsi?
Cohesin tuav cov viv ncaus chromatids ua ke kom txog thaum lawv sib cais ntawm anaphase thaum condensin reorganizes chromosomes rau hauv lawv cov qauv mitotic heev. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm cohesin thiab condensin. Tsis tas li ntawd, cohesin yog tetramer uas muaj plaub lub subunits, thaum condensing yog pentameric protein uas muaj tsib subunits.
Cov hauv qab no qhia txog qhov sib txawv ntawm cohesin thiab condensin.
Summary – Cohesin vs Condensin
Cohesin thiab condensin yog cov txheeb ze ntawm cov qauv thiab kev ua haujlwm, uas yog cov protein ntau. Lawv yog qhov tseem ceeb rau kev sib cais cov ntawv luam ntawm cov genome rau hauv cov menyuam ntxhais thaum lub sijhawm faib cell. Ob leeg muaj SMC cov proteins, thiab lawv yog cov qauv zoo li lub nplhaib. Txawm li cas los xij, cohesin yog tetrameric protein thaum condensin yog pentameric protein. Tsis tas li ntawd, cohesin muaj SMC1 thiab SMC3 thaum condensin muaj SMC2 thiab SMC4. Yog li, qhov no qhia txog qhov sib txawv ntawm cohesin thiab condensin.
